Phosphatase Acid ee dhiigga, go'aan, kelmadaha iyo heerka

Acid phosphatase - Insaymkaas ah in dedejisaa kala daatay ee u taagoo ee jirka. Determination of ay heerka in dhiig muhiim u ah ogaanshaha xaaladda caafimaadka. Waxaa jira dhawr nooc oo ah phosphatases acid, kaas oo ay wadaagaan qoral iyo isku, laakiin kala duwan oo aad u midba midka kale in la xiriira unugyada jirka ee, asal koromosoomyada, halabuurka.

wadaraha

enzyme Powered in deegaan acidic, sidaa magaca. phosphatase Acid waxaa laga helaa unugyada kala duwan iyo unugyada ku yaalaan laga yaabaa in lysosomes iyo wixii ka dambeeya. Tirada ugu weyn go'aamiyey in qanjirka 'prostate', iyo sidoo kale in unugyada xubnaha soo socda:

• beerka,
• beeryarada,
• dhuuxa lafta,
• Unugyada dhiigga (erythrocytes, platelets, macrophages).

In shaqeeyo caafimaad waxqabad ee phosphatase acid waa halkii uu hooseeyo. The wakiillo ka kala badh ay heerka lab ka kooban yahay phosphatase Prostatic ah, iyo wax alla wixii waa la wada baabbi'iyey in unugyada beerka iyo dhiig. The ensaymes ee jirka dumar sameeyay gabi ahaanba la burburiyay by beerka iyo erythrocytes, platelets.

Lysosomal phosphatase acid

Waxaa ku yaalla unugyada ugu. Its khaladkaasi waa cudur recessive autosomal, taas waxaa loo arkaa inay natiijada geeddi socodka dheefshiidka bahal ah. Symptomatology cudurka muuqato sida soo socota:

• lallabo iyo matag qasas;
• daciifnimo, luminta hufnaan;
• hoos u cadaadiska dhiigga;
• ee carruurnimada - opisthotonus (qalal ku dhaca u laabaya of ARC ka dib, bukaannada ku tiirsan yihiin dusha sare ee sariirta qoorta iyo cagaha oo keliya);
• dhiig.

Haddii heerka enzyme waa ku filan oo keliya in unugyada dhiiga cad, bukaannada inta badan ku xanuunsado exacerbations of cudurada raaga.

phosphatase acid Prostatic

Waxaa loo arkaa calaamad u ah hababka kansarka qanjirka 'prostate'. Noocan ah enzyme waxaa ka go'an iyo sida dareere abuur calaamad in tijaabooyin (kufsiga) ee. Acid phosphatase la sara kiciyaa, oo dhawr maalmood qalitaanka on qanjirka 'prostate' ama asalka biopsy ka dib.

tilmaame pH si mug leh for shaqaynaya saxda ah ee eulayska - 4.6. Activity muuqataa gaar ah ka dib markii nin qaangaadhnimada gaadho.

Currently, go'aaminta heerka phosphatase Prostatic sida calaamad kansarka markuu tagayu galay asalka oo xiiso kordhay antigen prostate-gaar ah, kaasoo kara inuu xaqiijiyo joogitaanka cudurka marxaladaha hore ee horumarinta. Si kastaba ha ahaatee, tilmaamayaasha phosphatase acid Prostatic waxaa muhiim ah in la saadaaliyo noqnoqoshada geedi socodka kansarka qaliin qaadidda qanjirka 'prostate' xagjirka ah ka dib.

Falanqaynta si loo ogaado waxtarka daaweynta ee kelyaha Prostatic benign iyo heley kale Prostatic.

phosphatase eritrotsitarnaja

Tani waa enzyme a polymorphic in ma aha oo kaliya in unugyada dhiigga cas, laakiin sidoo kale unugyada kale ee jirka. pH si mug leh ay u hawlgalka kala duwan 5.2 si 6.2.

Waxaa lagu ogaan karaa dhiig phosphatase acidic si loo caddeeyo aabbanimada. foomamka qaar ka mid ah enzyme waxaa la xiriira shuruudaha soo socda:

• cabista hidde in dhiig hemolytic;
• cudurada, taas oo ah waxa lagu gartaa horumarinta anemia hemolytic ee asalka cunaya digiraha,
• anemia in isticmaalka daroogada gaar ah ama soo koraya caabuq asal ahaan viral iyo bakteeriyada.

Waxaa jira noocyo of phosphatase acid erythrocyte toos ah ula xidhiidha xadgudubyada ka dhaca carruurnimada.

nooca qorayo of phosphatase acid

enzyme waa muhiim in cudurka of cudurka Gaucher. Tani waa cudur dhaxlay oo teedu raasamaal ee beerka, beeryarada, kalyaha, maskaxda, glucocerebroside sambabada (walxo organic ka tirsan baruurta). cudurka waxaa ku weheliyay koror weyn oo size of meydadka kor ku xusan, hoos u dhac af ee tirada unugyada dhiigga oo dhan, qalal, suuxdin caydi, dhimaal maskaxeed.

phosphatase acid qorayo waxaa sidoo kale loo arkaa calaamad gaar ah leukemia cell xaad. Cudurkaan waxaa la socda wax soo saarka ee xaddi weyn oo eulayska, wixii la goostay in dhiigga.

osteoclasts phosphatase

Loo yaqaan unugyada lafta osteoclasts mas'uul ka ah in ay u baabba '. Talaabadani waxay leedahay mudnaan muhim ah ee koritaanka lafaha iyo unit habeysan. xawaaraha sare ee lafo beesho weheliyo cudurada soo socda:

• cudurka (Avv bahal formation caadiga ah lafaha iyo xubno ay ka) Paget ee;
• hypercalcemia ee kansar;
• fawdada ah oo ka mid ah thyroid iyo qanjidhada parathyroid ;
• postmenopause isku dhafan oo osteoporosis.

Result - jab soo noqnoqda iyo khafiifinta horusocod ah ee qaab-dhismeedka lafta. Determination of osteoclasts phosphatase acid muujinaysaa heer sare ah ensaymes ee asalka ah heley kor ku xusan.

Diyaarinta iyo fulinta Baadhista xanuunada

Tilmaamayaasha taranta waxaa ka go'an in xaaladaha shaybaarka. Falanqaynta waa in la sameeyaa 2 maalmood ka dib markii laga bilaabo wakhtiga nidaamyada kale ee lagu ogaanayo. Haddii aad rabto in aad si loo qiimeeyo heerka phosphatase acid Prostatic, taas waa in la sameeyo ma hore ka badan 48 saacadood ka dib cad ka-qaadista, taataabasho of prostate, sanka kaadi. Xaaladdan oo kale ka soo hor jeedda, natiijada waxaa laga yaabaa in waxyaabaha wanaagsan been ah.

wax xayndaabka cilmi qaadeen calool madhan. Waxaad cabbi kartaa biyo ah oo keliya, la cabo shaah, kafeega, cabitaanka iyo sharaabka kale waa ka mamnuuc. Inta lagu jiro maalintii, waxaad u baahan tahay in la siiyo ilaa cabitaanka khamriga, dufan, suxuunta sigaar cabbin, 1 saac ka hor falanqaynta - sigaarka. saac ee la soo dhaafay bar ka hor qaadashada mid ah waxyaabaha la waa in la qabtaa in xasilloonida dareen buuxa.

Waayo, cudurka dhiig-arooriyaha loo isticmaalo, kuwaas oo ay serum fogaado hemolysis. Natiijooyinka sahankani waxay waxaa loo yaqaan maalinta ku xigta ka dib markii daraasadda.

Habka loo isticmaalo

Si loo xaqiijiyo heerka guud ee phosphatase acid loo isticmaalo farsamooyinka immunochemical la ogaado chemiluminescent. Isticmaal muhashada gaar ah ula falgalaan ensaymes qaarkood. nidaamyada Currently shaqaaleeyaan taagayo luminol perodoxida isku dhafan oo xal hydrogenperoxid ah. saamaynta waxaa lagu darayaa bilaabaha (tus, n-yodofenol) oo awood u kordhaya luminescence ee xal u dhowr kun oo jeer.

Waxaa jira habab kale oo isticmaala phosphatase xumadoodu iyo substrate AMPPD, samaynta habka cudur-aqoonsiga ka sii xasaasi ah. Faa'iidada ee habkan waa inaad wax ka barato xasiloonida ee reagents loo isticmaalo, ma khatarta shucaaca. Xudduudka ku salaysan adayga habraaca ogaanshaha.

caadi

Total assays phosphatase acid tilmaamay U / L. Its-beegyada uu ogolyahay kala duwan yihiin waxay ku xiran tahay da'da iyo jinsiga.

Tilmaamayaasha Normal Prostatic phosphatase acid - in ka yar 2.1 ng / ml. All tirooyinka sare ka muujin natiijada wanaagsan ee cudurka.

Marka heerka enzyme kordhay?

The xaaladaha ugu xun oo tallaabooyin tiro kor caadiga ah:

• Torombositobiiniya - tiro dhimay unugyada dhiigga ka mas'uul ah ay xinjirowga;
• thromboembolism - xannibaad ah Lumen ee thrombus weyn ee halbowlaha, ka derbiga markabka, ama lungemboli, kuwaas oo ku jira dhiiga go'ay;
• cudurka hemolytic - cudur ku weheliyay halligaad weyn ee unugyada dhiigga cas sii daayo tiro aan yareyn oo bilirubin dhiigga;
• horusocod Paget ee cudurka - qalab cudurada lafaha ee dheelitir u dhexeeya formation lafaha iyo burburinta qaybaha ay guushu ku dambaysta ah;
• myeloma - dabiiciga ah habka buro malignant, taas oo ka soo qayb galay B-limfosaytis, mas'uul ka ah ereygu wuxuu ahaa ee unugyada difaaca;
• cudurka Niemann-Pick - cudurada la iska dhaxlo lagu gartaa-shiid baruurta oo yaraada iyo raasamaal ee subaga in xubnaha waaweyn (beerka, caajisnimo, sambabada, wadnaha, kelyaha);
• maalmo yar ka dib markii qaliin looga sameeyay qanjirka 'prostate' iyo biopsy unugyada ay.

Acidic, phosphatase cawaaqib xumadoodu waxay - Koox ka mid ah ensaymes masuul ka ah geeddi socodka muhiim ah ee jirka ku jira. Waa la caawimaaddooda billowda reactions muhiim ah oo isku xigta. Go'aaminta heerka ensaymes ogolaanaya waqti si loo hubiyo helitaanka cudurada iyo waxa u horseedi si ay u taageeraan edbinta tayo sare leh oo dheeraad ah nolosha.