Cromoglicic acid. Description, tilmaamo, sababo

Waa maxay kromoglitsievoy acid? Tani waxay aad ka qalab la siiyo by article ka baran doonaan. Waxa kale oo aanu kuu sheegi ku saabsan dawooyinka ku jira walax ayaa sheegay in iyo in ay ka dhigan tahay.

foomka sii daayo, sharaxaad ku saabsan

Cromoglicic acid oo la soo saaray buufis ah neefsasho, sanka lagu buufiyo, dhibco lagu shubo indhaha iyo sanka lagu buufiyo. Sidoo kale qalab laga iibsan karaa qaab xal cad oo kaabsoosha budada ah, loogu talagalay neefsasho.

Mabda'a hawlgalka ee medicament a

Cromoglicic acid, qiimaha kuwaas oo hoos lagu tusay, xasilloon xuubka unug dabceen, iyo sidoo kale kaabsal ay. Tan waxa u sabab xanibaadda ee laga soo galo calcium galay unugyada.

Sidoo kale waa in la ogaadaa in wakiilka this hakiyo sii daayo dhexdhexaadiyayaal xasaasiyadda sida leukotrienes, histamine, iyo SG2 kale, unugyada kala duwan, kuwaas oo ku jira xabka ee Lumen reer hawomareenno iyo geedka bronki. Intaa waxaa dheer, walax this ka caawisaa si loo xakameeyo socdaalka ee monocytes iyo neutrophils.

guryaha

Cromoglicic acid muujinayaa sifooyinka soo socda:

• Aad waxtar u leh ka hortaga xasaasiyadda nooca degdeg ah ee dadka dhalinyarada ah, kuwaas oo aan weli u muuqday isbedel karin chronic ee sambabada. Waa in la ogaadaa in walaxda ayaa sheegay in aan hore u horumariyo tiraa bronchospasm.
• Soo bandhigaa oo saamayn xuub-dejinta. habka loo anada dhexdhexaadiye jawaab pulmonary caawisaa ka hortagga horumarinta jawaab hore iyo wajiga soo daahay oo neef (oo ay ku jiraan jawaab ku meersan difaaca iyo kuwa kale).
• saamayn xasiloon isticmaalka daawada waxaa lagu gaarayaa 2-4 toddobaad ka dib. Saamaynta daroogada ka dib markii maamulka hal waxaa muddo 5 saacadood.
• Natiijooyinka dareemi daaweynta cudurada xasaasiyad xubnaha muuqaal ah waxay dhacdaa dhowr maalmood ama toddobaad ka dib.

• isticmaalka daba dheeraaday ee daroogada yaraynaysaa inta jeer ee weerarada ee neefta bronki, oo aad bay u fududeeyaa ay Dabcan, yaraynaysaa baahida loo qabo qaadashada corticosteroids iyo bronchodilators.

kinetics

Cromoglicic acid nuugo ka soo mareenka-mareenka ee lacagta ah ee 10%, iyo ka dib neefsasho oo ah budada medicament iyo xal - 5-15% iyo 8% siday u kala horreeyaan.

Nuugid ka xub-axaleedka neefsashada hoos marka xaddiga dheecaan. fiirsashada ugu badan oo ah walaxda waa la gaari ka dib markii ¼ saac.

Qalabkani waxa aan metabolized. Its bar-nolosha ee 45-90 daqiiqadood. waxa soo saarka iyada oo mindhicirrada iyo kelyaha ee Joogaba, loo siman yahay oo ku saabsan, iyo sidoo kale iyada oo sambabada.

Maamulka Intranasal marinada dhiigga helo oo ku saabsan 7% samaynta. Iyada oo borotiinada plasma waxaa xidhana in 65%. Marka qalab this aan la metabolized oo raaca ee bile iyo kelyaha DASUURKA saacadood badh gudahood. Qayb ka mid ah walaxda firfircoon waxaa liqday aan nuugista iyo waxaa loo qoondeeyey by mareenka caloosha iyo mindhicirka.

maragga

Dhibciyo waayo, indhahoodu Antiallergic maamula la conjunctivitis xasaasiyad, keratitis xasaasiyad, keratoconjunctivitis, qalalan isha syndrome, cadaadis, daal isha xabka cuncun xubnaha muuqaal sababa dareen diidmo oo xasaasiyadeed.

Sidoo kale waa in la ogaadaa in qalab this waxaa loo isticmaalaa ka hortagga neefta bronki, bronchospasm iyo boronkiito daran leh Bos syndrome.

Daawada waa in foomka of wakiilada sanka lagu talinayaa in sanboorka iyo rhinitt xasaasiyad.

sababo

daroogada viewed aan qoray, waayo,

• diidmo,
• uurka (saddexda bilood ee ugu horeysay ee la neefsado);
• in caruurta (ilaa laba sano - foomka budo iyo kaabsoosha xal neefsasho, da'doodu tahay 5 - in qaab buufis ah neefsasho iyo maamulka sanka);
• naaska (maamulka sanka).

Kromoglitsievoy acid: edbinta

Neefsasho ee kaabsoosha for neefsasho in la sameeyo waa in la isticmaalayo spinhalera 4 jeer maalintii dura 3-6 saacadood (20 mg).

buufis dose neefsasho mitir maamula 1 dose (1 mg) afar jeer maalintii.

Solution for neefsasho la isticmaalayo daawada halkii ay noqol lahayd (20 mg) afar jeer maalintii. Ka hor inta la isticmaalayo dhalada waxaa si taxadar leh loo hurgufo oo ha hayo meel qumman.

dhibcood Sanka maamulo dadka waaweyn ee sanka midkiiba 3-4 lagu dhibciyo in 4-6 saacadood, iyo carruurta laga bilaabo 6 sano - 6 saac oo kasta 1-2 dhibcood. Ka dib markii muuqaalka kore ee saamaynta ku daweynta ee bareeg u dhexeeya qaadasho daroogada tartiib ah u kordhi laga yaabaa.

sanka lagu buufiyo codsan 1 dose in kasta oo sanka Dabcan 4-6 jeer maalintii. koorsada daawada waa 4 todobaad. Baabiiyo of daroogada Waa in la fuliyo si tartiib tartiib ah in ka badan hal toddobaad.

dhibcood Eye (tus, "cromoglycate Sodium") isticmaalaya 1-2 dhibcaha ah ee il kasta afar jeer jidhka maalin bareeg ah 4-6 saacadood. Haddii loo baahdo, tirada kor u keento ee 6-8 dhibcood.

waxyeellooyin

Mawduuca ku keeni kartaa:

• wareer, lalabo, sanka,
• cuncun iyo qallayl ee cunaha, madax-xanuun, afka oo qalala, haynta kaadida,
• cuncun neefsashada, sanka oo xirma, qufac, gubanaya indhaha, shaqada kelyaha oo yaraada, dheecaan kordhay dheecaanka sanka,
• finan maqaarka ah, barar conjunctival, isha qalalan, dareenka dhadhanka xun, dareenka jirka ajnabi ah, oo shaciir ah, lacrimation;
• anaphylaxis (oo ay ku jiraan dhib ku liqidda, maqaar cuncun leh, la sheegay ciyin, finan, barar bushimaha, wajiga iyo kaaha, hoos u cadaadiska dhiigga, neefta oo ku qabata).

Micne ah iyo qiimaha daroogada

Under waxa magaca ganacsiga iibin kromoglitsievoy acid? Tani "Ditek", "sodium nedocromil," "Ifiral", "Tilade", "kromogeksal", "Kromogen Easi-neefso", "Nalkrom", "Kromogen", "Kromoglin", "Kromosol", "nedocromil", "Kropoz "" Lekrolin "," Kuzikrom "," Stadaglitsin "," Hi-chrome ".

Qiimaha tahay waxaa laga yaabaa kala duwan, taas oo ku xidhan soo saaraha, foomka of daroogada iyo network farmashiyaha. Si kastaba ha ahaatee, celceliska acid kromoglitsievoy kharashka waa 100-250 rubles.