Mycobacterium tuberculosis: sheyga xogta astaamaha

Mycobacterium tuberculosis (Bacillus Koch ayaa) - bakteeriyada ul-qaabeeya garaam-positive oo sameysmi karaa qaab-dhismeedka thread-sida. Waxay yihiin acid u adkaysta oo weli ku jira wax badan oo la egyahay iyo wax ay derbiga, oo ay go'aamiso in ay iska caabin ah si dezveschestvam, qoraxda ama qalajiyo. sheyga Kuwanu waa xun yihiin midab leh formaldehyde aniline oo aqoonsadaan pathogenicity sare iyo hydrophobicity.

Waa in la ogaadaa in noocyada morphological gaarka ah ee bakteeriyada yihiin qaab-dhismeedka coccoid iyo L-foomamka, inkasta oo intooda badan oo ka mid ah - waa khafiif ah iyo si toos ah iyo Ulahoodii yar qalooca. Intaas waxaa sii dheer, Mycobacterium tuberculosis ka kooban in cytoplasm duuli badar (dhagaxyada gaar acid Labile).

Haddii aan ka hadlo guryaha dhaqanka bakteeriyada, kuwaas oo ah, inay yihiin anaerobes facultative ama aerobes. Ay feature sifo - koritaanka aad u gaabis ah, iyo baahida loo qabo protein iyo glycerin guul taranta. In warbaahinta dareeraha ah, sheyga, kuwaas oo ay u sameeyaan filim dusha a. On cufan ruuxaanta nafaqo Mycobacterium tuberculosis qaab taranka ee patina duuduubku midabka shiidan qalalan, muuqaalka deegaanada ay u eg cauliflower.

Tilmaamo pathogenetic

Arrinta ugu weyn ee pathogenicity - "factor xadhig". Waxaa glycolipids, kaas oo ay ilaaliyaan Bacillus Koch ka phagocytosis iyo go'aan ka nudaha sun dhaawici bukaanka aadanaha. Sidoo kale waa in la ogaadaa in kakan qaaxada M. waxaa lagu gartaa set oo ah cudur, si ay aqoonsi ku dhowaad marnaba loo isticmaalo guryaha antigenic.

Haddii cudurka qaaxada lagu kala qaado? saf-marka cudurka this jira saddex hababka isu gudbinta. Waxaa hawada, xoolaha jiran via caanaha (alimentary) iyo Carro hawada. Waa in la sheegay in qofka nolosha arrin inta badan xiriir la wakiilada qaaxada, laakiin cudur oo dhan ma yeeshaan waqti isku mid ah, iyada oo ku xiran iska caabin ah ee u shaqeeyo.

Bacillus Koch ayaa inta badan dhex gasho iyada oo mareenka-mareenka, kuwaas oo la qabtay macrophages ah. Dheeraad ah ee meel ka mid ah ingress bakteeriyada sameeyay diiradda bronhopnevmonichesky, sida barar ah ee qanjidhada gobolka. Isha ugu weyn ee cudurka waxay keeni kartaa pneumonia iyo guud qaaxada. At iska caabin sare ah Mycobacterium shaqeeyo joojiyaan in ay soo saari. Isla mar ahaantaa, waxay u dheer jidhka ku sii iyo shaqeysiin karaa iyada oo badan oo sano.

waa waxaan idinku leeyahay in la ogaado goor hore qaaxada u kordhiso fursada gabagabo wanaagsan cudurka. Maanta Waxaa sii kordhaya oo isticmaalaya hababka ugu dambeeyey ogaanshaha, ka mid ah taas oo ah meesha ugu horeeysa ayaa waxaa kujira reaction silsilad polymerase ah.

Marka PCR guuldareysto in la ogaado Bacillus TB Koch DNA xitaa in ay dhacdo lacagta ugu yar in xaqiijiyo horumarinta cudurka ma noqon karo hab kasta oo kale. Intaa waxaa dheer, PCR waa u fududahay in la ogaado iska caabin dee- daawooyinka shaqsi. Waxaa ku filan in ay kor u hiddo in mas'uul ka ah ee baakteeriyadu keento in rifampicin, isoniazid ama walax daroogada kala duwan, in qaadataa wax ka yar 48 saacadood ka yihiin.