Miisaanka kelli Low heparins: daroogada, calaamado muujinaya in loo isticmaalo

Therapy dhacdooyinka thrombosis iyo thromboembolic ma jiro xinjirowga lidka ku ah, oo ay ka mid Hoosaynta miisaanka kelli heparins. Waxyaabahani ee halabuurka ah ee daawooyinka bedeli xinjirowga dhiigga, oon ku soo celinta patency.

Noocyo ka mid ah daawada xinjirowga lidka toos ah

Fiirsaneysa inay hab ay of saamaynta xeryahooda antithrombotic in la ogaadaa waxa laga yaabaa in ay yihiin tallaabo toos ah iyo si aan toos ahayn. Kooxda ugu horeysay inta badan la isticmaalo ee walxaha.

Daawada xinjirowga saameyn toos ah ku leeyahay qaab-dhismeedka qaybsan yihiin miisaanka yar yahay heparins kelli iyo unfractionated. Waxa kale oo ay noqon kartaa si toos ah inhibitor thrombin, waa sida, tusaale ahaan, hirudin.

Feature miisaanka heparins kelli Low

Waxay si kala duwan u yeedhay xeryahooda fractionated kuwaas oo celcelis ahaan kelli miisaanka u dhaxeysa 4000 in 6000 daltons. hawlahooda la xiriira Iscelin aan toos ahayn oo ka mid ah dhismaha iyo hawlaha of thrombin eulayska. Noocan oo kale ah heparin saamayn fulyo on factor ee xinjirowga dhiigga o. Natiijadu waxay tahay daawada xinjirowga lidka ku ah iyo saamaynta antithrombotic.

Hoosaynta miisaanka ilmaha heparins kelli laga helay walxaha unfractionated ka epithelium xiidmaha doofaarka go'doonsan, inta lagu guda jiro geeddi-socodka depolymerization kiimikada ama enzymatic. Sidaas darteed of this reaction silsilad polysaccharide waa la soo gaabiyey by mid ka mid ah saddex-meelood meel ka mid ah oo dhererkiisu asalka ah, taas oo ka caawisaa si loo yareeyo Britain daawada xinjirowga lidka ku ah.

Waxaa jira kala duwan oo ku yar kelli miisaanka heparins, iyo dirka this ku salaysan yahay hababka loo helo xeryahooda cusbo-ka kooban.

soo saarista

daawooyinka waa xal isku duro maamulka subcutaneous ama xididka. Waxay caadi ahaan buuxiyey oo ku yaal ampules ama cirbadaha la tuuro.

Hoosaynta miisaanka kelli heparins aan la soo saaray in kiniiniyada.

daawo Intramuscularly looma isticmaalo.

Description "Gemapaksan" daroogada

Waxaa loola jeedaa in daawooyinka la saamaynta tooska ah xinjirowga. Walaxda firfircoon yahay oo ah qaab cusbo sodium enoxaparin, taas waxaa loo arkaa derivative ah heparin. beddelid waxay bixinaysaa adsorption sare marka subcutant iyo dareen yar yahay shaqsi ay maamusho.

Waxaa la soo saaray shirkadda Talyaaniga "Italfarmako SpA" sidii xal cad, midab lahayn ama iftiin-jaalle ah la isku duro oo la soo baakadeeyey ee cirbadaha ee 0.2, 0.4 ama 0.6 ml.

qiyaasta sodium enoxaparin waa in ay 2000 IU 20 mg, 4000 IU ilaa 40 mg iyo 6000 mg 60 IU. Walaxda firfircoon waa la kala diri ee biyaha duro daroogada.
sodium Enoxaparin teedu in qiyaasta ah 100 IU halkii 1 mg ah saamayn inhibitory sare on factor xinjirowga dhiigga o oo saamayn hoose antithrombin at a dose 28 IU halkii 1 mg.

Isticmaalka daroogada uruureen daweynta ee cudurada kala duwan noqonin mid horseeda in la kordhiyo waqtiga dalka ay dhiig la'aan.

Profilatikada qiyaasta sodium enoksaparinovaya uusan u beddelmin oo waqti thromboplastin qayb ka shaqeysiin, marnaba kuma xad-clumping ah dhiig xinjirowga sameeya iyo habka la xidhiidha si ay u taagoo fibrinogen ah.

miisaanka kelli Low heparins in fiirsashada weyn daroogada (6000 IU in 0.6 ml) waxaa loo isticmaalaa:

• waayo, daaweynta ee thrombosis in xididdada moolka;
• sameeyaan angina deganayn iyo xaalad muruqa myocardial cajiib ah infarcted isku dhafan oo acetylsalicylic acid,
• ka hortagga ah ee xinjirowga kordhay mudada of habka kelyaha sifeeya ah.

xal Hordhac dose subcutaneous 2000 IU iyo 4000 at 0.2 iyo 0.4 ml, siday u kala horreeyaan, waxaa loo isticmaalaa si looga hortago thrombosis iyo nidaamka xaalad thromboembolic arooriyaha:

• inta lagu guda jiro qalliin lafaha qof;
• sariirta bukaanka qaba la'aan neefsashada chronic ama nidaamka unit wadnaha 3 iyo nooca 4;
• cudurrada faafa ama rheumatic ba'an, halkaas oo ay jiraan arrin halis u xinjiro dhiig ah,
• bukaanada waayeelka ah,
• la dhigaalka baruur xad-dhaaf ah;
• marka therapy hormone.

Daawada waxaa loo isticmaalaa subcutant galay derbiga caloosha, in ay dambena iyo zone anterolateral.

Daawada waa u for Torombositobiiniya, dhiigbaxa, cudurada xinjirowga, cudurka kolit of xuub-axaleedka ee ka mid ah caloosha iyo mindhicirka yar, subacute endocarditis bakteeriyada, macaanka, macaanka, dareen sare iyo uurka.

"Gemapaksan" Daawo: qiimaha

Qiimaha duro oo ka kooban 2000 IU silingaha in 0.2 ml oo ah lix xabbadood oo 955 rubles.

Waayo, qiyaasta more daroogada "Gemapaksan 'safafka qiimaha laga 1,500 rubles halkii pack leh lix cirbadaha.

Description "Clexane" daroogada

Waxaa loola jeedaa in habka isku ku saleysan sodium enoxaparin. Soo saaray shirkadda French "Sanofi Aventis" sida xal la isku duro oo nadiif ah kaas oo noqon kara midab ama la towns wax yar ka hurdi ah.

Waxaa qiyaasta "Clexane" diyaarinta 10000, 8000, 6000, 4000 iyo 2000 IU of sodium enoxaparin in 1.0; 0.8; 0.6; 0.4; 0.2 ml of daroogada dareere ah, siday u kala horreeyaan. Walaxda firfircoon ee xalka waa 1 mg 1,000 IU.

Hoosaynta miisaanka kelli heparins yihiin macmalay ee cirbadaha galaas, oo laga yaabo in pack a 2 ama 10 gogo '.

Drug "Clexane" on thrombotic ka hortagga HIV iyo cudurada thromboembolic in xididka inta lagu guda jiro faragelin qalliin la xidhiidha lafaha, iyo kelyaha.

Xalka la durey subcutant at hareen dalalka thrombotic arooriyaha ee sambabada moolka iyo halbowlaha ah.

Drug angina dawayn nooca aan degganayn ee muruqa cajiib ah oo myocardial infarction lala kiniin "Aspirin".

"Clexane" Daawo: qiimaha

Qiimaha duro oo ka kooban 2000 IU 0.2 ml silingaha waa 175 rubles.

Mid ka mid ah dose unit of 4,000 IU la 0.4 ml of xoqin 280 doonayay inuu bixiyo 6,000 IU per ml 0.6 - 440 rubles 8000 IU per ml 0.8 - 495 rubles.

In diyaarinta "Clexane" Qiimaha halkii unit of 10 xabbadood oo leh qiyaas ah 20 mg, 40 mg oo 80 mg waa 1685, 2750, 4000 rubles.

Description "Fragmin" daroogada

qayb firfircoon ee daroogada waa derivative ah walax heparin wakiil sodium dalteparin. Waxaa la helay depolymerization by tallaabada ee nitrus acid , raaceen by nadiifiskeeda u isticmaalaya chromatography sarrifka ra'iyi. Dalteparinovaya sodium cusbo kooban silsilado polysaccharide sakhiray in sulphation, miisaanka celcelis ahaan kelli ah ee shan kun oo daltons.

Auxiliaries taag duro biyo iyo cusbo sodium chloride. medicament Belgian "Fragmin" Buuggan sharaxayaa sida xal loogu talagalay subcutaneous duro iyo maamulka xididka qaab dareere towns midab ah hurdi ama hufan.

Its sii daayo ee cirbadaha galaas oo 2500 IU per ml 0.2 monodose; 5000 IU per ml 0.2; 7500 IU per ml 0.3; 10,000 IU in 1.0 ml, 12,500 IU in 0.5 ml, 15,000 IU per ml 0.6; 18,000 IU per ml 0,72.

Drug "Fragmin" Buuggan ku talinaysaa isticmaalaya qiyaas ka hortag loogu talagalay gacanta ku ah hab xinjirowga dhiigga hawlaha kelyaha iyo haemofiltration loogu talagalay daaweynta ee kelyaha, si looga hortago formation of xinjiro in qaliin.

medicament waxaa maamula in la baabi'iyo ku lesions thromboembolic bukaanka jiifay.

Solution dawayn angina, deganayn iyo infarct gobolka cajiib ah myocardial muruqyada, thromboembolism arooriyaha astaamaha.

Description of daroogada "Anfibra"

miisaanka yar yahay Its heparins kelli loo gudbiyo shirkadda Ruush OJSC "Veropharm". Waxaa xal cad la isku duro, kaas oo noqon kara towns midab ama hurdi.

Salka hab waa cusbo sodium enoxaparin, kaas oo la jira waxaa laga yaabaa in 2000 IU per ml 0.2; 4000 IU per ml 0.4; 6000 IU per ml 0.6; 8000 IU per ml 0.8; 10,000 IU in 1.0 ml. biyaha debeda, waxaa loo isticmaalaa sida dareeraha.

Waxaa prepacked in ampules ama cirbadaha ee 1ml, kuwaas oo 2, 5, iyo 10 xabbadood ayaa la buuxiyey oo ku yaal baakad kartoonada.

Drug "Anfibra" barashada waxaa lagu talinayaa in ka hortaga xaalad thromboembolic marka ka hawlgala khalkhalgelinta iyo kelyaha ee daaweynta ee formation xinjir in weelashii qoto-jiifa.

Solution daaweynta dabiiciga ah ee aan degganayn ee angina iyo gobolka infarct muruqa wadnaha ee aan ilig Q on wadnaha ah.

Description of "Fraksiparin"

By miisaanka kelli hooseeyo heparins iska leh calcium nadroparin, kaas oo la helay intii lagu jiray geedi socodka depolymerization ah. taagoo Its waa glycosaminoglycans, miisaanka kelli celceliska taasoo la eg 4,300 Daltons.

Diyaarinta "Fraksiparin" (irbado subcutaneous) ee ay ka kooban waxaa ku jira hydroxide calcium iyo cusbo nadroparin, kuwaas oo kala diri ee biyaha isku duro.

Qiyaasta of qayb firfircoon waa 2850 ILA in 0.3 ml, 3800 ILA 0.4 ml, 5700 ILA 0.6 ml, 0.8 ME 7600 ml, 9500 ILA in 1 ml.

diyaarinta waa dareere ah oo hufan ama wax yar opalescent, taas oo uu leeyahay midab khafiif ah huruud ah ama gebi ahaanba Biyuhu.

cusbo protein Nadroparinovaya wanaagsan xidhana in antithrombin III, kaas oo keena Iscelin dedejiyey ee factor o. walaxda shidaa inhibitor bixinta Isbadal of factor unugyada, hoos ku nafwaayay dhiigga iyo kordhay permeability xuub dhiig xinjirowga sameeya iyo unugyada granulocytic. Sidaas qaadeen saamayn antithrombotic of daroogada.

Cirbadaha "Fraksiparin" qoro si looga hortago xaalad thromboembolic marka ka hawlgala khalkhalgelinta lafaha ee dabeecadda iyo kelyaha. Daawada waxaa maamula in bukaanka isagoo halis sare oo formation xinjir dhiig, la'aan ba'an ee neef-mareenka iyo cudurka wadnaha, kog deganayn, muruqa myocardial infarction cajiib ah in ay ka maqan Q-ruxruxo.

Isticmaalka daawada xinjirowga lidka ku ah ee carruur-dhalista

miisaanka kelli Low heparins ee uurka waxaa loo xilsaaray in bukaanka qaba dhiig xanuunada si aan sameeyay ee xinjiro dhiig mandheerta kaasi oo keeni in ay ilmo iska soo ridid, si preeklampsicheskomu of cadaadis dhiig oo sareeya, dhil ilmaha kuraasta la dhiigbax culus, dib u koritaanka uurjiifka ee ilmo-galeenka, taas oo keeni hooseeyo miisaanka ilmaha.

Daawada xinjirowga noocan oo kale ah waxaa lagu qoray haweenka booska la khatarta suurto galka ah ee formation xinjir in xididdada u qoto dheer, tusaale ahaan jirka hoose, iyo sidoo kale qabsamin halbowlaha sambabka.

therapy LMWH waa hab daran, taas oo bukaan uurka gala daroogada maalin maqaarka on caloosha ka yar.

Si kastaba ha ahaatee, inta lagu guda jiro kala sooca lahayn caafimaad oo la helay natiijada imtixaanka oo caddeeyo in isticmaalka daawada xinjirowga lidka ku ah sida inta badan waa aan sahla saamayn togan. Sidoo kale ogaaday in miisaankiisu kelli hooseeyo heparins therapy waxyeelayn kara jirka hooyada la xiriira dhiig korodhka iyo hoos u xanuun ka yareeyaha foosha.

Cilmi-baarisyadaasi waxay waxay muujiyeen in la baabiiyo daaweynta xinjirowga lidka ku badbaadin karto haween badan oo ka calaamado xanuun aan loo baahnayn iyadoo siday ilmaha.

tilmaamaha ku saabsan isticmaalka diyaarinta ku salaysan therapy miisaanka heparin kelli hooseeyo waxaa haweenka uurka leh.