Hypopituitarism: calaamadaha, hababka ogaanshaha iyo daaweynta

Hypopituitarism, calaamadaha, taas oo ay ka maqan yihiin cudurka ku filan lagu khaldaa oo leh calaamado of heley kale oo halis ah, waa cudur dhif ah qanjirka pituitary ee. In cudurkan, pituitary ee makrii mid soo saarta hormoonnada ku filnayn, ama aadan soo saaro mid ama ka badan hormoonnada lagama maarmaanka u ah hawlaha caadiga ah ee jidhka bini'aadamka.

Pituitary qanjirka - yar, qanjidh bean-qaabeeya ku yaal salka maskaxda, ka danbeeya sanka iyo dhegaha u dhexeeya. In kasta oo baaxadda yar, qanjirka this qabata shaqo muhiim ah, ay gacanta ku hayso hawlaha qarsoon oo xubnaha ku dhowaad dhammaan gudaha iyo xubnaha jirka. hawlaha Regulatory sameeyaa hormoono - la'aanta iyaga ka mid ah ayaa tilmaamaya laga yaabaa in hypopituitarism. Calaamadaha carruurta waxaa inta badan loo muujiyey in foomka of koritaanka faaqidaad iyo horumarka jireed, ee dadka waaweyn - xadgudub ku ah cadaadiska dhiigga iyo shaqada taranka.

Waxaa laga yaabaa in uu nool yahay ee Soon ee cudurka sida aad cabto daroogada ah, laakiin calaamadaha cudurka lagu hayn karo gacanta.

calaamadaha

cudurada falanqeeyay xaaladaha inta ugu badan waa horusocod ah ee dabiiciga ah. Waxaa had iyo jeer ma takhtarkaaga si degdeg aqoonsan karaa "hypopituitarism": calaamado ee carruurta iyo dadka waaweyn si lama filaan ah ku dhici kara ama horumariyaan si tartiib tartiib ah in ka badan dhowr sano. Inta badan calaamadaha Duugga iyo ma qof aad u yar in bukaanka muddo dheer si fudud uma fiiro ku filan.

Calaamadaha cudurkan way kala duwan iyada oo ku xiran hormoon ah, oo ka maqan jirka oo ay sabab u tahay cillad pituitary. Intaa waxaa dheer, waxaa muhiim sida fiiqan waa la'aanta ah ee walax gaar ah. Bukaanka ayaa laga yaabaa in ay la kulmaan:

• dareen daal chronic;
• hoos libido;
• kordhay dareen in kul hoose, qabow,
• rabitaanka cuntada oo luma.

Intaa waxaa dheer, kuwaas oo dareenka in calaamadaha cudurada kala yihiin:

• sharrixin khasaaro miisaankeedii dhan yahay;
• barara wejiga;
• anemia;
• dhalmo la'aan;
• haweenka - dareenka gubashada ah, caadada joogto ahayn, ama la'aanta oo dhanba, gumaarka timaha, awood la'aanta in ay soo saaraan caanaha naaska quudinta ilmaha dhashay;
• lab - luma timaha kordhaya on wejiga ama jidhka;
• carruurta - koritaanka yar yahay.

Marka si aad u aragto takhtar

Haddii aad ka shakisan at hypopituitarism, calaamadaha kor ku qoran, jadwal la wada xirfadle.

La tasho dhakhtarkaaga isla markiiba haddii si lama filaan ah u muuqday wax calaamado cudur ama waxaa weheliya madax xanuun daran, aragga indhaha oo isku darsamay, jaahwareer in waqti iyo meel, ama hoos u dhac af ee cadaadiska dhiigga. Tani ma aha hypopituitarism - calaamadaha dabeecadda this ayaa tilmaamaya laga yaabaa in qanjirka pituitary muujiyey dhiig burqada (apoplexy), u baahan in faragelin caafimaad oo degdeg ah.

sababaha

disorder Tani waxaa keeni kara cilladaha lagu dhasho, laakiin waxaa la badanaa soo iibsatay. Xaaladaha intooda badan, hypopituitarism sababa ah buro pituitary. Sida ay buradu ka noqday waaweyn, waxaa soo deysa iyo unugyada jirka magdhow, saamayn xun ku soo saarka hoormoonka. Intaa waxaa dheer, burada cadaadin karaa dareemayaasha optic, oon ku keenaya kala duwan ee cudurada iyo dhalanteed.

cudurrada kale, iyo sidoo kale xaalado gaar ah ayaa sidoo kale waxay dhaawici kartaa qanjirka pituitary iyo hypopituitarism kiciya (astaamaha, photos waxaan ku soo bandhigaynaa in this article). Calaamadaha cudurkan way kala duwan taas oo ku xidhan arrimaha sababay horumarinta cudurada. qodobada waxaa ka mid ah:

• madaxa dhaawacyada,
• Maskaxda ama pituitary buro,
• qalliin maskaxda;
• hababka daaweynta shucaaca,
• barar, shalalka (hypophysis);
• stroke,
• cudurada maskaxda faafa (tus meningitis);
• qaaxada;
• cudurada infiltrative (sarcoidosis - bararka xubnaha dhowr gudaha, Langerhans histiocytosis cell - disorder ah oo unugyo aan caadi ahayn keeni nabarro in xubnaha kala duwan iyo qeybaha jirka, inta badan ee sambabada, iyo lafaha, hemochromatosis - raasamaal xad-dhaafka ah ee birta ah ee beerka iyo unugyada kale);
• Dhiig bax badan oo marka ay dhalayso, taasoo dhaawici kartaa pituitary ee jilibka (Simmonds cudur-Glinski ama dhalmada galleeyda pituitary);
• Isbedelo hidde taas oo horseeday in xadgudubyada wax soo saarka ee hormoonnada ee qanjirka pituitary ah;
• cudurka hypothalamic - jab maskaxda, taas oo waxa uu ku yaalaa kaliya kor ku xusan qanjirka pituitary ah - sidoo kale waxay keeni kartaa hypopituitarism.

Astaamaha (sawir ka tarjumaya habka cudurka) kici, maxaa yeelay, hypothalamus soo hormoonnada u gaar ah ayaa nidaaminaya in hawlaha ay "deriska" qanjirka bean-qaabeeya.

Xaaladaha qaarkood, Bilowgii cudurka ayaa weli aan la garanayn.

Ka hor booqashada dhakhtarka

Tallaabada ugu horreysa waa in ay isku qoraan tashi caafimaad oo ladan. Haddii loo baahdo, waxa aad la isugeeyey takhasus ah in xanuunada hormoon - endocrinologist ah.

• Raadi ka hor haddii aad u baahan tahay in ay u hoggaansamaan shuruudaha si loo hubiyo saxnimada of tijaabada cudur-aqoonsiga.
• Samee liis faahfaahsan oo dhammaan astaamaha cudurka si aad u dhawrtaan at home. Haddii aad ka shakisan hypopituitarism, calaamadaha cudurka, at jaleecada hore la xidhiidhin cillad pituitary, sidoo kale waa in lagu daro liiska this.
• qoraal hagaajin ah oo xog muhiim ah oo shakhsi ah, oo ay ku jiraan isbedel baaxad weyn oo nolosha ama la taaban karo badala awoodda aad u xamili stress.
• Qor macluumaadka caafimaadka ee aasaasiga ah, oo ay ku jiraan qaliin dhawaan, horyaal oo si joogto ah u qaadataa daawooyinka iyo cudurada raaga. Dhakhtarka ayaa sidoo kale u baahan doontaa inaad ogaato haddii laguu wareejiyo dhaawac dhawaan madaxa.
• Soo qaado xubin ka tirsan qoyska ama saaxiib ma noqon doonaa oo kaliya diyaar u ah inay bixiyaan taageero moral, laakiin sidoo kale kaa caawin inaad xusuusataan oo dhan talooyinka khabiir.
• Samee liis su'aalo ah aad rabto in aad weydiiso dhakhtarkaaga.

su'aalo endocrinologist

Waxaa lagu talinayaa in la sameeyo liiska oo xiiso ugu su'aalahaaga ka hor si inta lagu guda jiro wada tashiga waa in aan la lumin hortiisa oo ka mid ah faahfaahinta muhiim ah. Haddii aad tahay hypopituitarism walaacsan (calaamadaha iyo daaweynta cudurada aad xiisaynayso), waxaa ka mid ah in aad liiska su'aalaha soo socda:

• Maxaa sababa calaamadaha cudurka iyo gobolka aan hadda?
• Ma suurogalbaa in calaamadaha cudurka sababa kale?
• Waxa aad u baahan tahay inay gudubto imtixaanka?
• Waa xaalad ku meel gaar ah ama joogtada ah?
• Waa maxay daaweynta ayaad ku talin?
• Sidee dheer ma u baahan tahay in aad qaadato daawooyinka lagula talinayaa?
• Sida aad la socon doontaa waxtarka daaweynta?
• Waxa aan qabaa cudur ah chronic. Sidee si loo hubiyo in daaweyn jiray isku mar ah oo dhan xanuunada?
• Ma inaan u hoggaansamaan wixii xannibaad?
• Ma jiraan analogues aad qoro daawooyinka?
• Waxaan jeclaan lahaa inaan si aad u hesho macluumaad dheeraad ah oo ku saabsan yahay waxa hypopituitarism. Calaamadaha iyo ogaanshaha waa cad; waxa alaabta ku saabsan daaweynta kala duwan ayaa kaala talin kara?

Ha ka waaban inaad weydiiso su'aalo kale, haddii inta lagu guda jiro wada tashiga aad rabto in aad ogaato wax takhasus gaar ah.

Oo waxa dhakhtarku yidhi

Endocrinologist, markeeda, waxaad weydiin doonaa su'aalo dhawr ah oo u gaar ah. iyaga ka mid ah, ay u badan tahay, waxay noqon doontaa waxyaabaha soo socda:

• Maxaad u malaynaysaa in aad leedahay hypopituitarism?
• Calaamadaha iyo sababaha cudurka oo aad naftaada ka heli, raacsan sharaxaad ka mid ah cudurka suugaanta caafimaad?
• Ma jiraan wax calaamado ah oo beddelay cudurada muddo?
• Ha aad aragto aragga?
• Ma waxaad u xanuunsado tan iyo madax xanuun aad u daran?
• Ma waxaad ka bedeshay muuqaalka? Waxaa laga yaabaa in aad laga badiyay miisaan ama helay hoos u dhac in mugga of timaha on jirka ah?
• Ma waxaad ka lumay daneyntii galmada? Waxaa aad caadada bedelay?
• Haddii aad u socotid at daaweynta la joogo? Or, laga yaabee, maray therapy ee la soo dhaafay la soo dhaafay? Waa maxay cudurada laga helay?
• Ma waxaad dhawaan umushay ilmo?
• Ma waxaad waayadan dambe heshay dhaawac madaxa ah? Ma daaweyn neurosurgical waxaa la soo dersay?
• Ogaado haddii qaraabadaada kuu dhow pituitary xanuunada ama cudurada hormoon?
• Maxay idinla tahay, waxay ka caawisaa si loo yareeyo calaamadaha?
• Waa maxay, in fikradaada, kordhinayaan in sii xumaanaysa ee calaamadaha?

Baadhista xanuunada

Haddii takhtarkaaga si degdeg ah looga shakisan yahay kartaa hypopituitarism? Calaamadaha iyo sababa gobolkaaga qabin hardiyi takhasus gaar ah ku rid, cudurka this bilowga ah, si loo xaqiijiyo in aad rabto in aad mari dhowr baaritaan si loo ogaado heerka hormoonnada kala duwan ee jirka. Sababta dejinta cudurka noocan oo kale ah uma shaqayn karo sidii dhaawac madaxa la soo dhaafay ama koorso buuxda oo radiotherapy - Sababaha halista waxay yihiin kuwo awood u leh in ay hogaamiyaan horumarinta cudurka.

Tirada baadhitaanada ogaanshaha caadiga ah waxaa ka mid ah:

• Tijaabooyinka dhiiga. Xad baaritaan sahlan oo lagu ogaan karaa deficiency hoormoonada gaar ah, kuwaas oo ka kacay sabab u ah cillad pituitary. Tusaale ahaan, baaritaan dhiig ayaa laga arki karaa on heerarka hoose ee hormoonnada soo saaray qanjirka thyroid, kiliyaha adrenal, ama xubnaha taranka, - la'aanta ah ee walxahan waxay inta badan la xidhiidha hawlaha yaraada qanjirka pituitary ee.
• Carbinta ama baaritaan firfircoon. Xataa khabiir ku ah way adag tahay in la aqoonsado hypopituitarism; calaamadaha ilmaha oo dhan waxaa laga yaabaa in la mid ah astaamaha kala duwan ee hiddo. Si aad u hesho natiijo sax ah ogaanshaha, dhakhtarkaaga u badan tahay inuu kuu gudbin doonaa rugta ku takhasusay cilmiga endocrinological, halkaas oo aad ka qaadan daawooyinka ammaan ugu horeysay dalab in ay kicin wax soo saarka ee hormoonnada, iyo markaa ka fiiri si aad u aragto mugga sida kordhaya ee dheecaan.
• maskaxda waxbarasho imaging. imaging resonance magnetic (MRI) ee maskaxda lagu ogaan karaa burada ah pituitary iyo cilladaha kale ee dhismaha.
• imtixaanada Eye. baadhitaan gaar ah loo ogaado in saamaynta koritaanka buro pituitary ee awood u leh inay arkaan ama aragti.

daaweynta

Hypopituitarism, calaamado soo bandhigay iyo kor lagu sharaxay, waa had iyo jeer natiijo ah halkii ay ka cudur oo kala duwan. Daaweynta sababaha asalka ay, in kiisaska intooda badan, meesha oo dhan oo ka mid ah calaamadaha cudurada hormoon la xidhiidha cillad qanjirka pituitary ee. Haddii therapy ku jirro hore sabab qaar ka soo baxday in aan macquul ahayn ama natiijo la'aan, waxa lagu daweeyaa hormoon therapy for hypopituitarism. Marka saamaynta la midka ah ee jidhka ma aha daaweynta aad u badan bedelka walxaha maqan. Qaadashada waa in qori kaliya endocrinologist ah xirfad sare leh, tan iyo markii ay xisaabiyaa shakhsiga ku saleysan iyo celin si adag hormoonnada kuwa iyo tiro ay waxaa lagu soo bandhigay in jirka caafimaad leh. Daaweyn laguugu beddelo socon karaa Meyeydaan.

Haddii burada ayaa sababay hypopituitarism, calaamadaha, daaweynta iyo daaweynta dhaqancelinta xiga waxay ku xiran tahay nooca dhismaha ah ee kasoobaxyo. Caadi qoray qaliin si loo soo saaro unugyada aan caadiga ahayn. Xaaladaha qaarkood, daawaynta shucaaca.

diyaarinta

Medicaments substituents lagu matali kara daawooyinka soo socda:

• Corticosteroids. daawooyinkan (tusaale adeegaan hawsha hydrokortisoni iyo prednisolone) hormoonnada bedelay ee gobolka caadiga ah soo saaray kiliyaha adrenal. Iyagu ma ku filan ay sabab u tahay yaraanta adrenocorticotropic. Corticosteroids afka laga qaato.
• "Levothyroxine" ( "LeVox" et al.). Daawada badalay hormoonka thyroid in cudurada ay khuseyso.
• hormoonnada jinsiga. Sida caadiga ah, waayo, nimankii waa testosterone loogu tala galay dumarka - estrogen ama estrogen isku dhafan oo progesterone. Haddii aad u malaynayso inaad qabto hypopituitarism, calaamadaha, iyo ka hortagga cudurada qanjirka pituitary waxaa laga yaabaa in la mid ah calaamadaha iyo qaababka ka hortagga xanuunada la xiriira hormoonnada jinsiga. Haddii aan caadi ahayn waxaa la ogaadaa dhakhtarka, si ay ugu bedesho daawooyinka hormone maqan loo isticmaalo qaabab gaar ah: gel ama testosterone irbado ragga iyo kiniiniyada, jel ama sharooto - loogu tala galay dumarka.
• hormone Growth. walax waxaa lagu magacaabaa in somatropin culuumta caafimaadka qaba cudurada hormoonada jidhka, galo jirka iyaga oo maraya duray subcutaneous. hormone Growth ogolaanaya jidhka si ay u koraan, hubinta koritaanka caadiga ah ee carruurta. sidoo kale dadka waaweyn ee magacaabi duro Maynee, hagaajinaysaa xaaladda guud ee bukaan-socodka, laakiin koritaanka caadiga ah oo aan la soo celiyey.

socodka

endocrinologist The socon doontaa heerarka hormoonnada aad dhiiggaaga ku jirta, si loo hubiyo in lacagta ku filan, laakiin ma-dhaafka ah ee walxaha muhiimka ah.

laga yaabaa in aad u baahan tahay si ay ula qabsadaan dose of corticosteroids, haddii aad tahay si xun u xanuunsan ama u oggolaan maayo stress halis ah jirka. Mararka sida, jidhka soo saarta oo dheeraad ah cortisol hormone. Beddelidda qiyaasta loo baahan karaa in kiisaska kuwa, marka aad qaadi hargab, idiin dulqaadan doonaa shuban ama matag, ama oggolaan doono qaliin ama daaweynta ilkaha. Bukaan badan ayaa qoray CT wareegsan ama MRI.