Hydrochloride Loperamide. hydrochloride Loperamide - diiwaanka

Waa maxay daawada "hydrochloride Loperamide '? Jawaabta dhamaystiran su'aashan waxaa laga heli karaa qalabka ay bixiyaan maqaalka. Intaa waxaa dheer, waxaan kuu sheegi doonaa si faahfaahsan oo ku saabsan sida loo qaato daawada, goorta iyo waxa qiyaasta.

warbixin guud

medicament "hydrochloride Loperamide" waa daroogada ah astaamaha oo waxaa badanaa loo isticmaalaa si loogu daweeyo shubanka ba'an iyo chronic. daroogada Tan waxaa lagu iibin bilaa warqad dhakhtar iyo iibiyo shiidaa farmashiye kasta oo qiimo ah la awoodi karo.

saamaynta pharmacological

Diyaarinta "hydrochloride Loperamide" barashada kaas oo la nested in kartoonka, yaraynaysaa motility iyo midab muruqyada siman ee xiidmaha iyo hakiyo peristalsis ee jirka, aad buu u sii kordhaya waqtiga transit ku jira ay ku. Sayidka, medicament soo bandhigay fulyo saamayn antidiarrhoeal. Waa in la ogaadaa in daroogada "hydrochloride Loperamide" ee uu bilaabo inuu si dhakhso ah u dhaqmaan. Marka dhaweynta daroogada this gudaha saamaynta ku daweynta waxay qaadataa 4-6 saacadood.

Pharmacokinetics

medicament noocan oo kale ah waxaa la nuugo xiidmaha waa arrin saboolka ah (40%). Maaddaama ay isku mid sare si ay receptors ka mid ah darbiyada xiidmaha, iyo sidoo kale heerka sare ah biotransformation ee marinka hore heerarka plasma beerka of qayb unmodified ka dib markii la helo hab 2 mg (1 kaabsal) waa in ka yar 2 ng / ml. fiirsashada ugu badan oo ah walaxda firfircoon ka dib markii xal loo isticmaalo waxaa soo gaadhay ka dib oo ku saabsan 2.5 saacadood, iyo ka dib kaabsulka ah - 5 saacadood ka dib. Qabanaya borotiinka plasma ku dhacaa 97%. daroogada Tan waxaa metabolized beerka iyo qayib ayaa qayb ka ah kaadida, sida la bile conjugates, iyo sidoo kale saxarada ah.

foomka Release daawada iyo inta ay ka kooban

Diyaarinta "hydrochloride Loperamide," isticmaalka kaas oo lagu qeexay oran, waa suuq foomka:

• budo Maandooriyaha xal.
• 2 kaniini mg, waxaa la geeyaa galay kartoonka 50, 30, 20 ama 10 gogo '.
• 2 kaabsoosha mg kaalinta galay xirmo 30, 20 ama 10 gogo '.
• kaabsoosha gelatin adag huruud ah, kuwaas oo ka kooban budada cad leh qayb firfircoon - hydrochloride Loperamide. kaabsal kasta waxa ku jira 2 mg oo ah walaxda firfircoon. Ka sokow medicament wakiil ka kooban yahay ee ay ka kooban iyo maaddooyinka kaabayaal: Rusheyn kartaa, galleyda, lactose, milmahayn magnesium iyo silica Kolloidol. kaabsoosha gelatin waa ganacsi la heli karaa in kartoonka ah 20 ama 10 gogo '.

Halkee kale oo ku jira hydrochloride Loperamide qayb firfircoon? Isticmaalka mukhaadaraadka this ee Farmashiiste iyo ogolaanaya daawooyin sida "Imodium" iyo "Diara". Si kastaba ha ahaatee, ay boqolkiiba in daawooyinka waa uga yar yahay in medicament la iibiyay.

Drug "hydrochloride Loperamide": waxa loola jeedo?

Sida laga soo xigtay tilmaamaha, daroogada waxaa loo baahan yahay in ay qaataan in arrimaha soo socda:

• Si caadiga ah kursiga ugu ileostomy.
• Marka xanuunada dheefshiidka iyo nuugista xiidmaha, kuwaas oo ay keento isbeddel lama filaan ah oo daran ah in cunto ama sidiisa caadiga ah ee cuntada (tusaale ahaan, inta lagu guda jiro cunto, Safar ah).
• Sida daroogada ah kaabayaal ah ee shuban faafa.
• Sida daaweyn astaamaha for shuban daran ama joogtada (xasaasiyad, shucaaca, daroogada ama asal dareen).

Sababo in isticmaalka daawada

Mararka qaarkood, aad uma isticmaali karo "Loperamide" daroogada (kiniin) ah? Tilmaamaha la siiyo dalalka dawo ma waxaa lagu talinayaa in:

• xirma xiidmaha;
• shuban, taas oo ka dhalatay ay sabab u tahay dabadhiig, enterocolitis pseudomembranous ba'an ama caabuqyada kale ee marinka dheef shiidka,
• diverticulosis;
• ulcerös kolit ba'an;
• diidmo.

Sidoo kale waa in la ogaadaa in daawooyinka kahortaga shubanka caruurta waa in lagu qoro oo kaliya in ay 4-sano. Waxaa intaa dheer, sida ay tilmaanta, waxay ka dhigan tahay "Loperamide" waa u in bilaha ugu horreeya uurka iyo nuujinta lagu jiro. Iyada oo daryeel weyn daroogada la qoray, waayo, beerka.

medicament The "hydrochloride Loperamide": tilmaamaha loo isticmaalo

Kiniiniga iyo kaabsuullada daroogada in la qaado oo afka ah oo aan calaaliyo. qiyaasta daawada waxay ku xiran tahay da'da adkaanta bukaanka iyo cudurka.

In shuban ba'an ee dadka waaweyn sida marka ugu horeeysa ee maamula 4 mg oo ka mid ah daroogada, ka dibna - 2 mg uqaadida kasta (haddii kursiga weli waa dareere ah).

In qiyaasta koowaad shuban raaga waa 2 mg. daryeel taageero ah ee dadka waaweyn waa in la dhisaa si inta jeer saxaro bukaanka ahaa 1 ama 2 jeer maalintii. The dose maalin walba ugu badnaan - 16 mg.

Saamaynta daweynta qaadashada daroogada sida a uu yeesho 48 saacadood gudahood. Haddii, si kastaba ha ahaatee, waayo 2-4 maalmood, ilaa la isticmaalayo ilaa 16 mg ah ee daawada maalin kasta, waxaad marnaba gaari karin natiijada la rabay, waa in aad had iyo jeer la tasho dhakhtar, kuwaas oo iyaga u gudbiyey in ay dib u soo ogaado. Isticmaalka daroogada waxaa loo soo celin karaa, laakiin kaliya daaweynta haddii gaar ah ama u labisnaayeen oo uusan caadi kursiga.

Sida waayo, carruurtii, daroogada noocan oo kale ah waa in la isticmaalaa sano oo kaliya 4 jir ah. dose ayaa sidoo kale waxa ay ku xiran da'da qofka bukaanka ah iyo adkaanta cudurka.

Ilmaha 4 ilaa 7 sano, daroogada waa in la siiyaa 3-4 jeer maalintii 1 mg. Duration ee therapy waa 3 maalmood. Carruurta laga bilaabo 7 ilaa 12 sano ay maamulaan afar jeer maalintii 1 kiniin ah muddo 5 maalmood ah. In ilmaha ba'an qiyaasta hore shuban waa in ay ahaataa 1 kaabsal. Qiyaasta ugu badan ee maalin kasta ee carruurta - 8 mg.

Haddii cunug uu shuban arkay ka dib markii fal kasta oo ku saxaroodaan in waqti dheer, mar kasta oo ay tahay in loo siiyo 1 kaabsal, laakiin aan ka badnayn 6 mg halkii 20 kg miisaanka jidhka maalintii. Haddii ilmuhu aanu musqusha ma tagaan wax ka badan 12 saacadood, iyo ka dib caadi ah soo dhaweynta saxarada soo bandhigay by daroogada waxaa lagula talinayaa in ay joojiyaan.

badinta daroogada

Xaaladdan oo ah qiyaasta xad dhaafka la daroogada this ee bukaan-socodka ah ee soo socda leexashooyinkaasi laga dheehan karo:

• rabshooyin in isuduwidda ee dhaqdhaqaaqa;
• Cidhiidh ee ardayda;
• maskax hurudda,
• dawakhsanaan;
• kordhay cabirida xaalada muruqa lafaha,
• mindhicir xirma;
• depression neefsashada.

Si loo daaweeyo dhakhaatiirta dalalka bahal ah sida inta badan maandooriyaha "Naloxone" waxaa loo isticmaalaa daaweynta astaamaha isku mar.

waxyeellooyin

Waa in la ogaadaa in ka dib markii codsiga ah ee diyaarinta bukaanka "hydrochloride Loperamide" kulmi karaan waxyeelo kala duwan. Inta badan waxay dhacaan iyadoo la isticmaalayo dheer ee daroogada. Sayidka medicament wakiil keeni karaan dhibaatooyinka soo socda:

• yaaqyaaqsi,
• aan caadi ahayn elektrolytka;
• matag,
• casiraad xiidmaha,
• wareer;
• gastralgia;
• lalabo,
• hypovolemia;
• dawakhsanaan;
• afka oo qalala.

In carruurta yaryar, daroogada oo inta badan keena xanuun ah caloosha, iyo sidoo kale finan maqaarka. Aad ayay u yar medicament "hydrochloride Loperamide" waxaa laga yaabaa in ay gacan ka haynta kaadida ama xirma xiidmaha.

Haddii 2 maalmood ka dib markii ifafaale kuwan ma baabi'i, iyo bukaanka ma dareemaan ma wanaagsan, waa in aad had iyo jeer la tasho dhakhtar, kuwaas oo dooran doonaan (oo la mid ah) alaabta kale ee. Haddii daroogada caawin, waxaa fiican in lagu hubiyo cudur keeni shuban.

isdhexgalka daroogada

Sida laga soo xigtay tilmaamaha, halka codsiga ah ee diyaarinta "hydrochloride Loperamide" iyo "Cholestyramine" hufnaan ugu horeysay hoos u dhici doono. Haddii aad u baahan tahay si ay u isticmaalaan daroogada la macnihiisu yahay "Co-trimoxazole" ama "ritonavir", markaa waa in aad ogtahay in ay bioavailability waxaa aad u kordhay.

ganaaxyada

Drug "hydrochloride Loperamide" waa in la qaato si taxadir leh ba'an ee kala dhantaalan, cagaarshowga. Waxaa sidoo kale aan lagu talinayaa in la isticmaalo in xaaladahan caafimaad oo halkaas Iscelin of peristalsis xiidmaha. Maqnaanshaha saameyn ku daweyn ku filan 2 maalmood ka dib markii maamulka ee daroogada ka dib waa la jecel yahay in loo tijaabiyo cudurka dhakhtarka iyo baabi'iyo shuban Bilowgii faafa.