Hormone 17-OH-progesterone. 17-OH-progesterone, heerka dhiigga

Ujeedada ugu weyn ee wareegga hormoon ee haweenka inta lagu jiro wareegga caadada - ugxan. Inta lagu guda jiro geeddi-socodka this, waa ay gacanta ugu jiraan hypothalamus ah. Xaaladdan oo kale, waxyaabaha nidaaminaya alaabooyinka waxaa ku qarisay in qanjirka pituitary jilibka: FSH iyo LH.

formation of ugxan samaynta

Wajiga pre-ovulatory ee wareegga caadada follicle ugxansiduhu Oo Qaliin dhowr transformations. isbedeladaan waxaa loo qaadan meel sarkhaansan FSH. Ka dib markii follicle gaaro size gaar ah a, iyo sidoo kale hawlaha functional in peak ovulatory LH waxaa la aasaasay. Waxaa lagu daahfuri doonaa "koriinkedu" ugxanta (heerka koowaad meiotic). Ka dib markii soconin wajigan ku dhacaa formation follicle, iyo iyada oo loo marayo taas oo ukun ah. bareeg u dhexeeya wajiga ugu sarreysa oo ugxan samaynta amarka of 36-48 saacadood ah. Inta lagu guda jiro barakaca wajiga postovulatory dhacaa caadi ahaan ukunta si ay ilmo-galeenka ee tube ugxan ah. In the case of bacrinta maalintii saddexaad-afaraad ee embriyaha waxay guskiisa galay saabka minka. Waxaa ay ku tallaalmid. Haddii ilmo ayaa ka dhacay, markaas ukunta inta lagu jiro maalinta ku geeriyooday tube ugxan ah.

Walxaha ku lug-nololeedka ah ee shaqada dumar taranka

In qanjidhada hormoonada jidhka loo sameeyay xeryahooda bayoloji firfircoon. Waxay yihiin yeedhay hormoonnada. Waa iyaga mahad via nidaamka hypothalamic-pituitary-ugxansiduhu iyo hubinta jiro waxqabad xorta ah ee xubnaha taranka. Xarunta kasta u qabata hawlo gaar ah. Mid ka mid ah walxaha ku lug leh geeddi socodka ee nidaamka taranka, waa 17-OH-progesterone. wajiga dalool la barwaaqaysan yahay koror weyn oo ay fiirsashada. Xarunta Tani waxaa ku dhexsameeysmo tiro yar oo ugxan. Kordhinta content oo ah walaxda waa heerka ugu sarreysa ee PH. Intaas ka dib, dhexe ee wareegga, fiirsashada waa la dhimay muddo gaaban. Progesterone in wajiga dalool gaabisaa badashada gooba ay dhiiri-estrogen. Xarunta The keentay waa la hoos geliyey wax isbadal. Sababta ugu wayn ee caadada waa joojinta kedis ah wax soo saarka by la yirahdo gulkroppshormon dhamaystirka wareegga progesterone. Tani waxay kordhin macmal ah stroma gooba wajiga luteal sameeyay reaction decidual. Waxa ay la mid tahay isbeddellada ka dhacaya bilowga ah ee uurka. Progesterone bixiyaa xeerka qanjirada dhuunta ilmogalenka, hoos u saabka contractility. Xarunta ayaa sidoo kale uu hakiyo caadada.

hormone 17-OH-progesterone. description

Waa steroids maamaan ah. Xaggeedaan cortisol adrenal sameeyay sarkhaansan yihiin falgalka sida 11-b-21 hydroxylase ama hydroxylase. 17-OH-progesterone dumarka synthesize kartaa androstenedione. Qoraalkan waa maamaan ah testosterone oo estradiol. Waxaa la sameeyay ee ugxan iyo qanjidhada adrenal. progesterone-17-OH joogo dhiigga ee xorta ah iyo xudduud la borotiinada side sida transcortin oo albumin. Maqnaanshaha hoos u fiirsashada walax unugyada labka iyo dheddiga. In the case of rakibida ukunta ee ugxan, la yirahdo gulkroppshormon sii si ay u soo saaraan.

fiirsashada

17-OH-progesterone kor u subaxdii. waxyaabaha ay Ugu Yar shaaca ka qaaday habeenkii. Inta lagu jiro maalintii, oo ay heer kala duwan. Iyo ka-fiirsashada xarunta kala duwan inta lagu jiro wareegga caadada. korodhka A weyn ee heerka arkay maalin ka hor peak LH ah. Tan waxa la wajiga fiirsashada ugu badnaan (bartamihii wareegga-). Inta aad uurka leedahay, content xoolihiisiina u kordhay. 17-OH-progesterone, heerka of wixii la goostay ayaa la raacayo da'da carruurta waxaa ku jira xaddi yar. uruureen waaweyn waxaa laga helaa oo kaliya ee muddada bacrin ah oo isla markiiba ka dib dhalashada. Xaaladdan oo kale, in carruurta yaryar dhicis content waa mid yara weyn. Intii lagu guda jiray toddobaadkii ugu horreeyay ee uu hoos u dhaco heerka la xidhiidha. Waxaa lagu xusay korodhka horusocod ah inta lagu guda jiro qaangaadhnimada. Muddadan, dhallinyarada progesterone-17-OH si tartiib tartiib ah gaadho fiirsashada la mid ah sida dadka waaweyn.

Maxaad ugu baahan tahay baaritaan dhiig?

17-OH-progesterone waa wax soo saarka dhexe. Si kastaba ha ahaatee, uu daraasadda waa talaabo muhiim ah in cudurka of heley kala duwan. By maragga waxbarasho waxaa ka mid ah dhalmo la'aan, hirsutism, xanuunada wareegga. Marka kelyaha dushooda sida daawada loogu talagalay dadka bukaanka ah ay maamusho therapy bedelka steroid. Si loo qiimeeyo falanqayn ay ku oolnimada waxaa sidoo kale loo xilsaaray. 17-OH-progesterone bartay ee dhallaanka. Daraasad fiirsashada Its deficiency looga shakisan yahay 21-hydroxylase. Deficiency of enzyme this lagu arkay nooca kelyaha lagu dhasho.

Diyaarinta imtixaanka shaybaarka

Haddii dhakhtarka uusan haysan waqti kasta oo kale, dhiigga ku siinayaa ilaa on saddexaadna wuxuu u soo wareegga maalintii shanaad. Baadhitaanka ayaa la sameeyay calool madhan subaxdii. Lama oggola isticmaalka kafeega ama shaaha. Ogol yahay in ay cabto biyo cad. Tan iyo cuntada ee la soo dhaafay ka hor inta deeq dhiigga waa in ay ugu yaraan siddeed saacadood. Khubarada daraasaddan waxa hormone aan habboonayn ee wajiga labaad on 20-23 maalinta ka fiirsan. Haddii muddada wareegga of 42 maalmood, saami dhiig ah waa la fuliyay maalintii th 35. Maalinta 23-ka mid ah wajiga koowaad weli sii. Heerka progesterone waa la dhimay, laakiin ma muujinayaan failure ah wajiga luteal ama anovulation. Waxay ka dhigaysa mid aan caqli lahayn si ay u qabtaan daraasad fiirsashada inta ay uurka leedahay iyo in ay qaataan dawooyinka kasta. Xaaladdan oo kale, sare 17-OH-progesterone - iska caadi ah. content noocan oo kale ah ee daryeelka dhalmada looma baahna.

fasiraadda natiijada

Sida kor ku xusan, heerka caadiga ah ee hoormoonka progesterone, 17-OH ku xiran tahay da'da. Muhiimadda iyo galmada mawduuca. fiirsashada waxaa ka go'an in NG / ml. content fiicnayn carruurta jirta ilaa bil ah - 0-16,63; 1-2- bilood. - 1,8-9,7; 3 bilood. - 0,07-1,7. Bukaanka ka yar hal sano - 0-1,65; ilaa 3 sano - 0-0,99; 3 ilaa 10 - 0,07-1,69. heerka la ogolaan waayo, nin - 0.5-2.1. Waayo, haweenka wajiga dalool - 0,41-2,72; ovulatory - 0,33-2,8; luteal - 0,33-2,8. In saddexda bilood ee ugu horreeya dhalmada ka progesterone-17-OH waa in la joogo in fiirsashada ah 1,17-5,62 noqon; Second - 1,17-6,7; saddexaad - 1,24-11. In content postmenopausal isitcmaalo 0,13-0,51.

kelyaha

Waa cudurada wadnaha, shalalka. Sida caadiga ah uu yeesho sabab u ah deficiency of falgalka ku lug leh ereygu wuxuu ahaa ee steroids. La'aanta xeryahooda laga yaabaa in darajo kala duwan ee darnaanta. In bilaw in kelyaha lagu dhasho yeesho virilization (formation of sifooyin rag ah dumarka). Xaaladaha daran, deficiency enzyme ah dhirfinaya xadgudubyo halis ah ee ereygu wuxuu ahaa ee steroids, khasaaraha cusbo, kaas oo noqon kara naf-gooyada ah. deficiency Qayb ahaan enzyme la helay ee dadka waaweyn, waxa kale oo uu noqon karaa mid lagu dhasho ee dabiiciga ah. Xaaladdan oo kale, markii hore xadgudubyada ka dhaca foom qarsoon, oo had iyo jeer lama dareemo ee carruurnimada. Avv hoos ensaymes leedahay dabeecad horusocod karo. Under saameynta ay arrimo bahal kasin kordhisaa la jaaniska isbedel functional iyo morphological in qanjidhada adrenal, daliilka la mid ah ee lagu dhasho syndrome. Sidaas darteed horumarka galmada carqaladeeyey ee dhallinyarada. In badan oo ka mid progesterone, 17-OH diiradda ay hawlaha on ereygu wuxuu ahaa ee androgens. xeryahooda Kuwani wareegaya yaraantaadii oo ka cadhaysiinina gabdhaha hadal of sifooyinka galmada ah nooca lab ah. Sidaa darteed, waxbarasho ee ay fiirsashada waa lagama maarmaan in la go'aaminayo waxtarka daawaynta helay.

The deficiency khatar badan oo ka mid ah enzyme 21-hydroxylase

soo bandhigaa xarunta La'aanta hoos formation aldosterone. Tani hormone adrenal bixiyaa xeerka biyo iyo cusbo dheelitirka, dib u dhac ku jirka ah ee cusbo. In dhallaanka, waxaa jira a "khasaaraha dhibaatada." Waayo, xaaladda sida lagu gartaa raasamaal ah dheecaan oo ku jira tiro badan oo ah. Isla mar ahaantaana jidhka si firfircoon uga baxaan cusbo lagama maarmaanka ah. Sidaas darteed, content potassium bilaabmin si loo kordhiyo, iyo sodium - hoos u dhac. kaafi enzyme Qayb gartaa tirtirayaa sawirka kiliinikada. Shaki deficiency muuqan ee asalka ah ee xadgudubyada baaluqo iyo koritaanka ee baaluq, at da'da weyn - la dhalmo la'aan iyo si daciif ah inta lagu jiro wareegga caadada, gabdhaha - la hirsutism.

gunaanad

Waxqabadka hormoonnada jinsiga waa mid ka mid ah arrimo go'aaminta ma aha oo kaliya hawlaha nidaamka taranka ee haweenka. reaction The xeryahooda, ay xasiloonida iyo waxqabadka, ka qayb qaadashada geedi socodka kala duwan sida caadiga ah, sidoo kale ay goobjoog ka ahaayeen fiirsashada ah fiicnayn ayaa saameyn ku leh horumarka guud ee jidhka iyo caafimaadka guud ahaan. ku takhasusay ayaa ka digay in weecasho wax ka heerarka jira dawo ma yihiin had iyo jeer oo calaamad u ah cudurada. In xiriir this, kiis kasta oo ma u baahan tahay daaweyn. Si kastaba ha ahaatee, dhakhaatiirta ku talinaynaa in ay si joogto ah dhiig ku deeqaan si falanqaynta shaybaarka, in ay gudbaan imtixaanka. cudurada qaarkood waxay leeyihiin nooc ka mid qarsoon iyo cudurka dhicis keenaysaa in cawaaqib xun. Muhiimad gaar ah waa gobol ka mid ah haweenka oo hormoon ah. Ma loo aqoonsaday in xanuunada caruurnimada da'da socdo, oo sababay hakad ku shaqaynaya oo ka mid ah hababka taranka iyo kuwa kale ee jirka. Xaaladaha qaarkood, dhalmo la'aan - mid ka mid ah dhibaatooyinka ugu badan oo degdeg ah ayaa maanta - waa natiijada cudurka daahay. Waayo, bukaanlayda qaadato Daaweyn laguugu beddelo, sidoo kale u baahan baaritaan iyo baaritaan dhiig oo joogto ah. Natiijada ogolaan ma aha oo kaliya in ay qiimeeyaan awoodda ku-daweynta ee daroogada ah, laakiin sidoo kale si ay ula qabsadaan nidaamka codsiga ay.