The daroogada 'Diovan'. Tilmaamaha loogu isticmaalo iyo sharaxaad kooban

"Diovan" waa firfircoon angiotensin II antagonist gaar ah receptor. Waxaa loogu tala galay maamulka afka. Sababo la xaqiiqada ah in ku lifaaqan daroogada 'Diovan' tilmaamaha, user ku baran karaan ku saabsan Jidka tallaabo. daroogada Tani blocks ka receptors AT1, mas'uul ka ah angiotensin II. Sidaas darteed, fiirsashada plasma of angiotensin II, kaas oo u dareen nooc hoosaadka furan receptor AT2, kordho.

Waxaa jira dhowr calaamado muujinaya in loo isticmaalo "Diovan" daroogada. Tilmaamaha loogu isticmaalo u ogolaanaya in ay iyaga ka akhriso. Waxay kala yihiin:

- wadnaha (chronic);

- hypertension.

"Diovan" Kiniinnada waxaa maamula si ay u kordhiyaan jaaniska ah badbaadada bukaanka qaba Wadnaxanuun myocardial ba'an, taas oo ah mid qasan by cillad bidix ventricular, systolic ama bidix la'aan ventricular, tilmaamayaasha xasiloonida geodynamic.

Saamaynta daroogada this for wadnaha ku salaysan tahay awooddiisa ah inuu baabi'iyo

- badashada cell keenta in habeysan oo ka mid ah wadnaha, xididdada dhiigga, kelyaha,

- dareeraha ee jirka ku jira;

- vasoconstriction;

- kicinta Avv-dhaafka ah ee hormoonnada sida aldosterone, endothelin, Horomonka iyo catecholamine kale.

In daaweynta of hypertension tallaabo "Diovan" daroogada arkay laba saacadood ka dib. The yareysey dhibic cadaadis lagu arkay ka dib markii 5 saacadood. tallaabo kiniiniyada sii socoto in ka badan 24 saacadood. noqnoqoshada isticmaalka "diovan" cadaadiska ugu badan waa la dhimay qiyaastii by todobaadkii labaad ama kan saddexaad, iyo dayactiro heer in muddo dheer. Waa in la ogaadaa in si waafaqsan xogta bixiyeen lifaaqan daroogada "Diovan" edbinta, joojinta kadis ah isticmaalka daroogada noqonin mid horseeda in la kordhiyo kadis ah in cadaadiska ama waxyeellooyin kale caafimaad oo loo kasin.

Mararka ay dhacdo kiniinada "Diovan" waxaa loo isticmaalaa ka dib markii Wadnaxanuun myocardial, walaxda firfircoon daroogada - Valsartan - dhimista 25% ah ee khatarta dhimashada.

Ka hor inta isticmaalka dawadan waa in si fiican u yaqaanaan sababo in la helo "Diovan" daroogada. Tilmaamaha in daroogada ku qoran liiska iyaga ka mid ah:

- uurka;

- nuujinta;

- dareen gaar ah in uu joogo wax kasta oo qayb ka ah ee ka kooban of daroogada.

Sidoo kale, si taxaddar sare waa in la qaato kiniin "Diovan":

• cunto xaddidan ee sodium,

• bukaanka shaaca ka qaaday laba geesood ah stenosis halbowlaha kelyaha ,

• in failure cagaarshowga, ka dhacay dhanka ah asalka ah oo xirma biliary;

• Bukaanka qaba la'aan kelyaha,

• inta lagu guda jiro shuban, matag.

Ka dib markii reading ku saabsan daroogada dib u eegista 'Diovan', waxaad baran kartaa saabsan dhibaalka dhanka kale ee caadiga ah sida:

- cudurada viral,

- Neutropenia,

- wareer postrualnoe,

- hypotension orthostatic.

In qaar ka mid ah kiisaska wax dhif ah ayaa dhici kara cudurada sare neef-mareenka, hyperkalemia, hogaga, hurdo la'aan, suuxid, dhuun xanuun, luminta libido, wadnaha oo shaqadiisa gaba, hypotension, qufac, iyo xanuun caloosha, shuban, vertigo ah, dhabar xanuun, asthenia, dareemid daal , barar. Aad ha u yaraatee, laakiin ay dhici karaan rhinitt, Torombositobiiniya, pruritus, finan, madax xanuun, lalabo, vaskulitis, anjioedema, arthralgia, cillad kelyaha, myalgia.

Ayaa ku tilmaamay in kooban ayaa sidoo kale calaamadaha badinta daroogada this. Si looga hor, ka hor inta codsanaya tilmaamaha "Diovan" diyaarinta isticmaalkeeda waa in si taxadar leh loo arkaa macaamilka. Waxa ay muujinaysaa in jidka loo maro qaadashada daroogada iyo qiyaasta, sidoo kale sharaxaad ka mid ah oo dhan calaamadaha xad dhaafka ah iyo gargaarka degdegga ah tallaabooyinka.