NSAIDs - taasi waa waxa daroogada? NSAIDs: qoraalka. Jiil cusub oo ah NSAIDs

NSAIDs gaabiyay - in aad u sheegto oo ku saabsan wax? Haddii aan, waxaanu kuu soo jeedinaynaa dhowr ah oo ay ku ballaariyaan jahooyinka iyo bartaan in ay matalaan, kuwaas oo afar warqado dahsoon. Read maqaalka - iyo wax kasta oo noqon doona cad. Waxaan rajaynaynaa in uu yahay oo keliya ma aha wargelin ah, laakiin sidoo kale oo xiiso leh!

NSAIDs - qoraalka

Waxaan ma noqon doonto dheer in daaliyaan Akhristeyaasheena mugdi ah. NSAID u taagan tahay non-steroidal anti-bararka - daroogada in aannu mar aad loo jecel yahay oo caan ah, in ay awoodaan in ay isku mar la baabi'iyo xanuunka iyo in la yareeyo bararka ee xubnaha kala duwan ee jirka ku jira ... Haddii ilaa hadda aad marna kacay baahan yahay therapy NSAID - this la oran karo waa ku dhawaad mucjiso ah. Waxaad - mid ka mid ah luckies dhif ah, dhab ahaan, caafimaadkaaga la Doonayey Meejiisa Shalay karaa!

Ka hor su'aasha xigta oo markiiba noo sheegeen oo ku saabsan fasiraadda erayga "non-steroidal". Taas macnaheedu waxa weeye in daawooyinka hormoonnada ah, ie, Waa kuma jiraan in ay qaab-dhismeedka kasta hormoonnada. Waxaa kale oo aad u fiican, sababtoo ah waxaan oo dhan og tahay inta uu noqon karaa mid aan la saadaalin karin oo khatar hormoonnada.

The NSAIDs ugu caansan

Haddii aad u malaynayso in NSAIDs - daroogada oo magacyadoodiina dhif hadlay nolol maalmeedka, ka dibna aad tahay qalad ah. Dad badan oo xitaa ma ogsoona sida uu inta badan waxaan leenahay in la isticmaalo daawooyinka ka hortaga bararka non-steroidal si loogu daweeyo of nno kala duwan in la socon tartanka aadanaha tan iyo eryidda ee Aadan iyo Xaawo Jannada ka Kusch. Fiiri liiska lacagaha sida, sida xaqiiqada ah qaar ka mid ah iyaga ka mid ah waa in aad golaha daawada guriga. Sidaas daraaddeed, in NSAIDs ka mid ah daroogada sida:

• "Aspirin".
• "Amidopyrine".
• "Analgin".
• "Piroxicam".
• "Bystrumgel".
• "Diclofenac".
• "Ketoprofen".
• "Indomethacin".
• "Ketorol".
• "Naproxen".
• "Ketorolac".
• "Flurbiprofen".
• "Voltarengel".
• "Nimesil".
• "Diclofenac".
• "Ibuprofen".
• "Indopan".
• "Ipren".
• 'Upsarin UPSA ".
• "Ketanov".
• "Mesulid".
• "Movalis".
• "Nise".
• "Nurofen".
• "Ortofen".
• "Thrombotic ACC".
• "Ultrafen".
• "Fastum".
• "Finalgel".

Haa, waxaa dhammaan daawooyinka NSAID. Liiska soo baxay, inkasta oo waaweyn, laakiin, dabcan, waa fog ka dhameystiran. Oo weliba waxaa weli ku siinayaa fikrad of kala duwan ee daawooyinka casriga ah non-steroidal anti-bararka.

qayb ka mid ah xaqiiqooyinka taariikheed

The daroogada horeysay NSAID heer hoose ah ayaa la ogaaday inay dadka tan iyo wakhtiyadii hore. Tusaale ahaan, ee qadiimiga Masar, in laga takhaluso kulaylka iyo xanuunka waxaa loo jilif safsaf - il dabiiciga ah ee salicylates iyo mid ka mid ah daawooyinka marka hore aan steroid ahayn ee bararka ka hortaga. Oo wakhtigaas dhakhaatiirta loola dhaqmo bukaanada ay ka cabanaya xanuun wadajir ah iyo qandho, decoction of beeyo hadaaska ah iyo liin - waxay sidoo kale ku jira salicylic acid.

In bartamihii 19-qarnigii waxay bilaabeen inay horumariyaan chemistry, oo dar dar geliyay horumarinta dawooyinkooda. Markaas waxbarashada ayaa la sameeyay darey daroogada ugu horeysay oo ka soo jeeda alaabta ceeriin cuntada. salicin nadiif ah ka soo jilif safsaf waxaa ku dhexsameeysmo 1828 - waxay ahayd tallaabada ugu horraysa ee la abuurayo caan ah noo dhan "Aspirin".

Laakiin waxa ay noqon doontaa sanado badan ka badan oo cilmi-baaris hor daroogada dhalan doona. dhacdo Grand dhacay 1899. Dhakhaatiirta iyo bukaan ay si deg deg ah u mahadnaqayo faa'iidooyinka daroogada cusub. In 1925, markii ay burburtay Europe faafa kuwa cabsida leh ee hargabka, "Aspirin" noqday badbaadiye ee dad badan. In 1950, daroogada anti-bararka ah non-steroidal ahaa ee Guinness Book of Records sida suuxinta la mugga ugu weyn ee iibka. Waa hagaag, ka dibna farmasiiyada ee la abuuray iyo daroogooyinka kale magnyl anti-bararka (NSAIDs).

In waxa cudurada anti-bararka daawooyinka aan steroid ahayn waxaa loo isticmaalaa

kala duwan ee codsiga waa NSAIDs aad u ballaaran. Waxay aad wax ku ool ugu doctoring cudurrada ba'an iyo chronic labada Ulasocto xanuun iyo barar yihiin. Maalmahan waa in kasii daraasaddan cilmi-baarista ee waxtarka daawooyinkaan in daawaynta cudurada wadnaha iyo xididdada dhiigga ee. Iyo xaqiiqda ah in ay la isticmaali karaa xanuun dhabarta, loo yaqaan ayaa maanta ku dhowaad dhammaan (NSAIDs osteochondrosis yihiin badbaadada dhabta ah).

Halkan liiska xaaladaha cudurka, haddii ay dhacdo in muujinaysaa isticmaalka NSAIDs kala duwan:

• Fever.
• Madax xanuun, jaf.
• calool kelyaha.
• Rheumatoid arthritis.
• Turqo.
• Arthrosis.
• Osteoarthritis.
• Dysmenorrhea.
• arthropathies bararka (psoriatic arthritis, spondylitis ankylosing, Reiter ee syndrome).
• Postoperative xanuun syndrome.
• Xanuun syndrome fudud in dhaawacyada dhexdhexaad ah iyo isbedel bararka kala duwan.

kala soocidda ee NSAIDs siday u kala dhismeedka kiimikada

By reading this article, aad hore u arkay in daawooyinka aan steroid ahayn ee bararka ka hortaga jira dad badan. Si aad iyaga ka mid ah maraan ugu yaraan wax yar ka wanaagsan, aynu heli soocidda hantida kuwan. First of dhan, waxay loo qaybin karaa sida soo socota: Group - Koox ka mid ah acid iyo NSAIDs - taagayo non-acid.

hore waxaa ka mid ah:

- salicylates (isla markiiba dib ugu yeeran kartaa "Aspirin").

- taagayo acid phenylacetic ( "Aceclofenac," "Diclofenac" et al.).

- pyrazolidine (metamizole sodium, lagu yaqaan in inta badan oo naga mid ah sida "Analgin" "phenylbutazone, iwm).

- oxicams ( "tenoxicam," "Meloxicam", "piroxicam" "tenoxicam").

- The taagayo of indole acid acetic ( "Sulindac", "indomethacin", iwm).

- derivative Propionic acid ( "Ibuprofen", iwm ...).

Kooxda labaadna - taasi waa:

- sulfonamide derivative ( "Celecoxib", "Nimesulide", "Rofecoxib").

- alkanones ( "nabumetone").

Qoondaynta oo ah daawooyinka aan steroid ahayn ee bararka ka hortaga ee ay ku oolnimada

Isticmaalka NSAIDs marka la daweynayo osteochondrosis iyo cudurrada kale ee wadajirka ah oo awood u leh macno shaqeeyaan yaabab. Laakiin, nasiib daro, ma daawooyinka oo dhan waa u siman yihiin in ay ku oolnimada. Madaxda Absolute la oran karo waa iyaga ka mid ah:

• "Diclofenac".
• "Ketoprofen".
• "Indomethacin".
• "Flurbiprofen".
• "Ibuprofen" iyo qaar ka mid ah daroogooyinka kale.

The daroogada ku qoran in la soo sheegnay waxaa laga yaabaa in saldhig; t. e. salaysan iyaga on la soo saari karaa oo kaalay network farmashiyaha NSAIDs cusub, laakiin magac oo kala duwan, oo inta badan ka bedelay qiimo sare. Si aan si aad lacag baabba 'ah oo aan waxba, u bartaan sida loo noqon cutubka xiga. Macluumaadka ku qoran waxa ku jira, kaa caawin doontaa in aadan noqon qaldo la doorasho.

Waa maxay in la raadiyo marka aad dooranayso daawo

NSAIDs - taasi waa qaybta ugu, daawooyinka casriga ah u fiican, laakiin, soo socda si farmashiyaha, waxa fiican in laga war hayo qaar ka mid ah Gudigga ah. Waa maxay? Laakiin akhri!

Tusaale ahaan, doorashada waa inay u fiican yahay si ay u iibsadaan a "diclofenac", "Ortofen" ama "Voltaren". Oo aad isku daydo inaad wax ka weyddiin ka farmashiistaha, taas oo ka mid ah daawooyinkan ugu fiican. Inta badan, waxaa lagugula talin doonaa mid ka mid ah in uu yahay mid qaali ah oo dheeraad ah. Laakiin xaqiiqada ah in kooban oo ah daawooyinka waxay leeyihiin isku dhaw. Farqiga A ee magacyada maxaa yeelay, way soo saaray shirkado kala duwan, kan aabbaha iyo alaabooyinka yihiin midba midka kale ka duwan. Isla ayaa laga odhan karaa, tusaale ahaan, "indomethacin" iyo "indomethacin" ama "ibuprofen" iyo "Brufene" iyo wixii la mid ah. D.

Si loo fahmo wareer ah, had iyo jeer si taxadar leh u eegto baakada, sababtoo ah waxaa jira waa in la siiyey maal daroogada firfircoon ugu weyn. qoraal ah oo kaliya, waxa ugu badan tahay warqado yaryar.

Laakiin sidaas maaha oo dhan. Dhab ahaantii, ma aha sidaas u fudud! NSAID-analoogga ah daawo la yaqaan waxa laga yaabaa inaad si lama filaan ah waxay sababi dareen-celin ama dhinac saamaynta xaasaasi ah in aad marna ka hor la arkay. Maxaa arrinta? Sababta ee lagu daro dheeraad ah, kaas oo, Dabcan, waxba ma baakada la qoray jiifsan laga yaabaa. Sidaas, waa in aan wax dheeraad ah iyo edbinta bartaan.

Sabab kale oo suuragal ah in natiijo kala duwan ah daroogada analog - farqiga in qiyaasta. Dad juhalo ah inta badan ma fiiro kasta si, laakiin aan micne lahayn. Ka dib oo dhan, yar ee tabletochki size ku jiri kara dose "faras" oo ah walaxda firfircoon. Taa waxaa ka duwan, kiniinka ama irbada weyn ku dhacaya ka kooban yihiin buuxiyo by sida ugu badan ee 90 boqolkiiba.

Mararka qaarkood wakiilada yihiin sidoo kale laga heli karaa foomka retardirovannoy, E. Sida daawooyinka kordhiyay (sii dheerayn) tallaabo t.. Muqaalka muhiimka ah waa awooda daawooyinkaan waxaa si tartiib ah u nuugo, sidaas saamaynta ay socon karaa maalin dhan. diyaarinta noocan oo kale ah ma u baahan tahay in aad cabto 3 ama 4 jeer maalintii, oo ku filan in ay dose hal. Tani feature ee daroogada waa in la tilmaamay on baakada ama in horyaalka. Tusaale ahaan, "Voltaren" qaab dhac loo yaqaan "faafiyo Voltaren."

List of analogues daroogada loo yaqaan

Waxaan ku soo daabacnaa this sheet Qiyaanoole yar rajada ah in ay kaa caawin doona inaad si fiican u maraan ee baakadaha badan farmashiyaha qurux badan. Ka soo qaad in aad isla markiiba u baahan NSAIDs wax ku ool ah si ay u debciyaan osteoarthritis xanuun. Qaaday sheet shilika Somaliland ah oo u aqri liiska ee soo socda:

- analog "Diclofenac", ka sokow ka "Voltaren" hore u soo sheegnay iyo "ortofen" sidoo kale "Diklofen", "Dikloran", "Diklonak", "Rapten", "Diklobene", "Artrozan", "Naklofen".

- "indomethacin" iibin hoos wata magac sida "Indomin", "Indotard", "indomethacin", "Revmatin", "Indobene", "Inteban".

- analogues "Feldene" "Erazon", "pyroxene", "Roksik", "pyroxene".

- analogues "Ketoprofen", "Flexi", "Profenid", "Ketonal", "Artrozilen", "Knavon".

- A caan ah oo jaban "Ibuprofen" waxaa laga heli karaa qayb ka mid ah daawooyin sida "Nurofen", "Reumafen" "Brufen", "Bolinet".

xeerarka NSAID

NSAIDs la xidhiidha laga yaabaa in tiro ka mid ah waxyeelo, sidaas waxaa lagu talinayaa marka ay maamusho si ay u dhawraan xeerarka soo socda:

1. Akhri tilmaamaha iyo tixraaca talooyinka in uu ka kooban - waxaa loo baahan yahay!

2. kaabsoosha Marka ay maamusho ama kiniin ku qaado hal galaas oo biyo ah - this ilaalin doonaa calooshaada. Sharcigan waa in la raaco xataa haddii aad cabto daroogo ugu casrisan (taas oo ah waxaa loo arkaa ammaan) sababta oo ah taxaddar dheeraad ah marna i dhaawaceysaa,

3. Ha jiifsan ka dib qaadashada daawada nus saac ah. Xaqiiqada ah in ciidanka of cuf ku biirin doonaan in ay marinka ka wanaagsan ee kaabsal hoos hunguriga,

4. Laga soo bilaabo cabitaanka khamriga waa in la dayacay, sida la wada xidhay by NSAIDs iyo khamriga - darka khatar ah oo sababi kara cudurrada caloosha kala duwan.

5. Mid ka mid ah maalinta, waa in aad qaadataa laba daroogada non-steroidal kala duwan - waxa aan u kordhin doonaa natiijo wanaagsan, laakiin halkii ay koobayaa waxyeellooyinka.

6. Haddii aanu dawada caawin, la tasho dhakhtarkaaga, waxaa laga yaabaa in aad tahay qiyaas aad u yar ayaa loo xilsaaray.

Dhibaatooyinka ay keento iyo gastropathy non-steroidal

Hadda waxaad ka heli doontaa waxa gastropathy NSAID ah. Nasiib darro, oo dhan NSAIDs muujiyaan waxyeelo badan. Waxay saamayn gaar xun ee mareenka caloosha iyo mindhicirka. Bukaan-socodka rabshin laga yaabaa in daliilka sida

• Lalabo (oo mararka qaarkood aad u xoog badan).
• Laabjeex.
• Matag.
• Dyspepsia.
• Dhiig caloosha iyo mindhicirka.
• Shuban.
• boog dyspepsia iyo caloosha.

All dhibaato ee kor ku xusan waa gastropathy NSAID. Sidaas awgeed, dhakhaatiirta si joogto ah kuu qori bukaanada ay in ay isku dayaan dose ugu hooseeya ee suuragalka ah ee daroogada classic non-steroidal anti-bararka. Si loo yareeyo waxyeellada daran ee caloosha iyo mindhicirrada, waxaa lagu talinayaa in marna qaadan daawooyinkan calool madhan, oo saas yeelo oo kaliya cuntada culus ka dib.

Laakiin dhibaatooyin la xiriira xubnaha dheefshiidka - ma ahan oo dhan dhibaatooyinka soo raaca in ay yihiin awood u soo saara ka mid ah NSAIDs ah. daawooyinka qaarkood si xun u saameyn karaa wadnaha iyo kelyaha. Mararka qaarkood ay qaadanayeen ay wehlin karaan madax xanuun iyo wareer. dhibaato kale oo khatar ah - waxay leeyihiin saameyn aad u ba'an ku intra-articular carjawda (of course, kaliya isticmaalka muddada dheer). Qarni Nasiib wanaag, ganacsi heli cusub ee NSAIDs, kuwaas oo inta badan ka reeban cillado kuwan.

daroogada magnyl anti-bararka ah ee jiilka cusub

In labada sano ee la soo dhaafay, shirkado badan oo dawooyinka ah loola horumarinta a NSAIDs casriga cusub, kaas oo, wada jir ah ula maamulka ku ool ah oo xanuun iyo barar, lahaa waxyeelo badan ee suurtogalka ah. dadaalka Farmashiistayaasha loo caleemo saaray guul - koox dhan oo ah jiilka cusub ee daawooyinka ayaa la soo saaray, wuxuu u yeedhay xushay.

Bal qiyaas - daawooyinkan hoos kormeer caafimaad lagu cabbay kartaa koorsooyinka aad u dheer. Iyo waqtiga la qiyaasi karo ma aha oo kaliya toddobaadyo iyo bilo, iyo xataa sanado. Daawooyinka in kooxdan aysan haysan saameyn aad u ba'an ku carjawda articular, waxyeelo ka badan ka yar yihiin iyo sii ficil ahaan ma keenaan dhibaatooyin.

jiil cusub oo NSAIDs - waa daawooyin sida:

• "Movalis".
• "Nise" (aka - "nimulid").
• "Arcoxia."
• "Celebrex".

Qaar ka mid ah faa'iidooyinka aan kuu sharxi doona tusaale ahaan ka mid ah "Movalis". Waxaa laga heli karaa sida kiniin ah caadiga ah (7.5 mg iyo 15) iyo in dabada of 15 mg, iyo in ampules galaas maamulka muruqyada dhexdooda (sidoo kale 15 mg). Waxay ka shaqaysaa daawada waa mid aad u jilicsan, laakiin waqti isku mid ah mid aad u hufan, maalintii oo dhan waa ku filan tahay oo kaliya hal kiniin. Marka bukaanka tusay daaweyn muddo dheer, waayo, arthritis daran of hip ama jilibka kala goysyada, "Movalis" waa fudud maarmin.

qaabab kala duwan, taas oo NSAIDs waxaa laga heli karaa

Inta badan daawooyinka anti-bararka caan magnyl laga iibsan karaa oo loo isticmaalo ma aha oo kaliya ee foomka of kiniiniga iyo kaabsuullada maamulka afka, laakiin sidoo kale in cadar, jel, shumacyo iyo xal la isku duro. Oo sida xaqiiqada ah waa mid aad u wanaagsan, sababtoo ah kala duwanaanta taas oo ka dhigaysa waxaa suurto gal ah in xaaladaha qaarkood si looga fogaado dhaawac inta lagu guda jiro daawaynta saarka isku mar ah oo ka badan saameyn ku daweyn degdeg ah.

Sayidka, jiil cusub oo NSAIDs in osteoarthritis loo isticmaalaa sida irbad, saamayn badan ka yar on mareenka calool-ka. Laakiin waxaa jira koox flip in qadaadiic this: marka intramuscularly ay maamusho, ku dhowaad dhammaan daawooyinka aan steroid ahayn soo saari kartaa dhibaatooyin - galleeyda oo unug muruqa. Taasi waa sababta NSAIDs duro majirin muddo dheer.

Guud ahaan, irbado waxaa loo magacaabay by sii daridda ah ee cudurrada bararka iyo side of kala goysyada iyo dhabarta, Ulasocto xanuun aad u daran loo dulqaadan karin. Ka dib markii xaalad bukaan-socodka hagaajinaysaa, waxa uu noqonayaa mid suurto gal ah in lagu baddalo si kiniiniyada iyo hab dibadda ee foomka of cadar.

dhakhaatiirta sida caadiga ah isu geeyo foomamka qiyaasta kala duwan, go'aaminta waxa iyo markii keeni kartaa lacagta ugu weyn bukaanka. Gunaanadka waa cad yahay: haddii aadan rabin in ay naftooda Nacfi iyo is-daweynta cudurrada iska caadiga ah sida dhabar xanuunka hooseeyo ama osteoarthritis, caawimaad weydiiso in hay'ad caafimaad, in uu yahay meesha aad awoodi doona inuu ku caawiyo.

Ma isticmaali karaa NSAIDs inta aad uurka leedahay

Dhakhaatiirta si adag ugu talinaynaa qaadashada NSAIDs haweenka uurka leh (gaar ahaan ganaax ee saddexda bilood ee saddexaad), iyo hooyooyinka kuwaas oo naaska. Waxaa la rumeysan yahay in kooxdan oo ah daroogo si xun u saameyn karaa uurka ilmaha caloosha iyo isaga ka dhigi curyaanimo kala duwan.

Sida laga soo xigtay ilo qaar ka mid ah, waa dawo aan dhib lahayn, loo arkaa by badan sida "Aspirin", waxay kordhin kartaa halista dhicin hore ee uurka. Laakiin mararka qaarkood dhakhaatiirta qalliinka for muujinaya qoray loogu tala galay dumarka daroogada firfircoon (ku xaddidan ee heerka qiyaasta ugu yar). In kiis kasta oo gaar ah, go'aanka waa in la sameeyaa by dhakhtar aqoon u leh.

In uurka, haweenka inta badan waxay leeyihiin dhibaato dib iyo waxaa loo baahan yahay si ay u xaliyaan dhibaatada this isticmaalka daroogada antiinflammatory magnyl sida aad u hufan oo degdeg ah. Xaaladdan oo kale, loo oggol yahay isticmaalka "Voltaren Saliid." Laakiin - mar - madax-bannaan oo ay la isticmaalo waxaa suuragal ah keliya in saddexda bilood ee koowaad iyo labaad, ee uurka ka dib isticmaalka this daroogada ee awoodda badan waa la ogol yahay oo keliya ka yar kormeer dhakhtar.

gunaanad

Waxaan idiin sheegay waxa ay ogaayeen naftooda ku saabsan NSAIDs. Deciphering gaabiyey, dirka daawooyinka, xeerarka ay soo dhaweynta, macluumaad ku saabsan dhibaalka dhanka - waxay noqon kartaa mid waxtar leh ee nolosha. Laakiin waxaan doonayaa in aan arko baahida loo qabo daawooyinka ka kacay Akhristeyaasheena sida ugu macquulsan. Sidaa darteed, kala leexdaan, waxaan aad doonayso caafimaad oo xoog leh oo wanaagsan!