"Neuromidin": war

The qayb weyn ee firfircoon ee daroogada "Neuromidin" edbinta waxaa lagu magacaabaa isku dhaf ah oo adag - ipidacrine. Its guryaha pharmacological ay sabab u tahay isku-dar ah laba saamaynta dhaca heerka kelli. The ugu horeysay oo ka mid ah - awood u leh inay abuuraan go'doomin ah permeability potassium of xuub, iyo tan labaad - suuragalnimada in Iscelin of hawlaha cholinesterase. Sidaas darteed of muujinta saamayntooda, daroogada "Neuromidin" wanaajisaa tallaabada of wakiilada sida epinephrine, serotonin iyo histamine on acetylcholine muruqa siman.

daroogada waxay leedahay awoodaha soo socda pharmacological. Waa wax ku ool ah ku dhiiri galin kartaa habka la isugu gudbiyo muruqyada, iyo sidoo kale qayb ka xasilin garaaca wadnaha ee ubucda u ah habka dareemayaasha jirka. Isticmaalka daroogada wanaajisaa contractility xubnaha muruqa siman, iyo marka lagu daro, waxay bixisaa kicinta dhexdhexaad yimaada habdhiska dhimirka.

daroogada waa amaan oo ku filan marka loo isticmaalo in la raacayo shuruudaha lagu taliyay, waxa uu leeyahay maya saamayn teratogenic iyo mutagenic daroogada ma aha tallaabo cudurka kansarka iyo immunotoxic. Saameynta xun ee nidaamka hormoonada jidhka aadanaha aan arkay.

Ipidacrine awood u si degdeg ah nuugo galay maamulka ka dib. In ay fiirsashada plasma ugu badnaan waxaa soo gaadhay ka dib oo ku saabsan hal saac in haddii daawada loo qaaday qaab kiniin ah. Haddii daroogada la intramuscularly maamula, midda ugu badnaan la gaaro wakhtiga badhkiis. In diyaarinta unugyada plasma si deg deg ah ay timaado in haraadiga ay tahay 2% oo keliya. Ipidacrine bar-nolosha ee 40 daqiiqo, heerka uu xiriirka ay la leedahay borotiinada uyeelaysaan kuwo 40-50%. daroogada "Neuromidin" buugan waxay ku talinaysaa isticmaalaya shuruudaha soo socda. Waa dawo waxtar u leh kala duwan lesions of habka dareemayaasha jirka. Gaar ahaan, waxaa loo isticmaalaa in lagu daaweeyo neuropathy, noocyo kala duwan oo neuritis, curyaannimo bulbar, xanuunada xasuusta.

Qori daroogada si uu bukaanka qaba cudurka Alzheimers iyo noocyada kala duwan ee waallida, iyo sidoo kale xaaladaha lesions habdhiska dhimirka ee asal ahaan kala duwan. Daawo "Neuromidin" waxaa loo isticmaalaa in therapy isku dhafan ee daaweynta ee habdhiska cudurada demielinizuyuschih.

Ka hor inta la isticmaalayo daawada waa in si taxadir leh loo soo bartay si uu u tilmaamo talinayo in la isticmaalo daroogada "Neuromidin" in kaabsoosha iyo kiniiniyada. baahida loo qabo Tan waxa u sabab xaqiiqada ah in wakiilka waxaa loogu talagalay daaweynta kala duwan oo ku filan ballaaran oo cudurro, iyo in kiis kasta oo hab gaar ah, labada qaab ee maamulka, iyo qiyaasta ee.

daaweynta Pi la daroogada this waa inay ogaadaan in ay jiraan contra-muujinaya, taas oo dawada laguma talinayo. The sababo ugu muhiimsan waxaa ka mid ah cudurka qalalka, angina, cudur oo kala duwan mindhicirka. Waa inaad ka fogaataan haweenka uurka leh iyo sidoo kale kuwa taas oo ay jirto diidmo ah in qaybaha daroogada.

In daaweynta daroogada, "Neuromidin" edbinta dhigayaa suuragalnimada in tiro ka mid ah saameynadaan liddiga ah: cuncun, finan, lallabo, madax wareer. Haddii dhacdooyinka sida dhacaan, waxaad u baahan tahay in ay hoos u qiyaasta ama joojin muddo ah qaadashada daroogada.

taxaddar gaar ah marka la helo daawo in la arkay kuwa bukaanka waxaa laga helaa nno wadnaha.

Waxaan ku talinaynaa in aadan qaadan daawada halka baabuur-wadidda.

Iyada oo ah qiyaasta xad dhaafka ah ee qayb daroogada buuga "Neuromidin" ku qeexayaa calaamadaha sida bronchospasm, indhaha-biyood. Sidoo kale waxaa jira kiisas of myositis, matag, iyo garaaca. In xaaladaha ugu daran, waxaa laga yaabaa gariir iyo bilawga kooma.

Haddii daawada qayb-sumowga waa in la isticmaalaa M-holinoblokatory: sulfate atropine, tsiklodol oo isla markiiba la tasho dhakhtar.