Daawo "tamoxin" edbinta ku saabsan codsiga la xidhiidha koox ka mid ah daroogada antineoplastic leh saamayn magnyl iyo antiestrogenic. Isticmaalka wakiilka this kiciya ama la sii daayo hormoonnada pituitary, yaraynaysaa bararka iyo wax ku ool ah oo joojisay horumarinta neoplasms. Laga bilaabo ka blocks daroogada aqbaliddoodii horeysay tallaabo ee estrogen isbuucyo yar, iyadoon dhibaato waxyeelo aan loo baahnayn la xidhiidha juqda unugyada. In bukaanka lab ka cabanaya cudurka Shahwada, isticmaalka "tamoxin" cadhaysiiyaan kordhiyo uruureen testosterone plasma. Haddii aan la baadho pharmacokinetics wakiilka anti-burada, wuxuu bilaabaa inuu noqon firfircoon oo kaliya soddon daqiiqo ka dib markii maamulka ka dib, oo gaarey heerka ugu sareeya ee shan ilaa toddoba saacadood.
daroogada Available "tamoxin" kiniin yellow, oo ay ku jiraan sida qayb weyn ee toban, labaatan, soddon ama afartan milligram tamoxin sitraydh. maaddooyinka dheeraad ah: cellulose, istaarijka sodium, milmahayn magnesium, lactose iyo povidone. qolof ah ku jira in ay tones polyetylen halabuurka, titanium dioxide iyo hypromellose. Intaa waxaa dheer, qadar yar oo ah hadiyad lactose ee daroogada.
Ka dhig kiniinka "tamoxin" diiwaanka ku talinaysaa in bukaanka qaba kansarka gooba, prostate ama ugxan, iyo qanjirada caanaha thoracic. Sidoo kale, daawada waa mid aad waxtar u leh burooyinka ee kelyaha ama melanoma. Sarkooma la mid tahay si ay u bilaabaan qaadashada daroogada "tamoxin". Tilmaamaha loogu isticmaalo qoraalada iyo natiijo wanaagsan ka isticmaalo daaweynta etiologies kala duwan uzlovidnyh qaababka.
Qaado wakiilka antitumor this gebi ahaanba la mamnuucay in ay dhacdo dulqaad shaqsi sitraydh tamoxin ama wax qaybaha kale ee daroogada. Leukopenia, thrombophlebitis, uurka, muddo nuujinta, caadka iyo noocyada halista ah ee cudurka wadnaha ayaa sidoo kale sababo in this daroogada, "tamoxin" - tilmaamaha loo isticmaalo lacagta fiiro in ay. Intaa waxaa dheer, ha qaadan in bukaanka qaba la'aan cagaarshowga ama kelyaha. Iyadoo daryeelka darafkii ugu magacaabi pill "tamoxin" la thrombocytosis, Torombositobiiniya, cudurada maskaxda, ama hypercalcemia.
Tani daroogada ee kooxaha qaar ka mid ah bukaanada waxay keeni kartaa saxarada, lallabo, matag, cholestasis, hoos rabitaanka cuntada, shuban, iyo dhexgalka beerka. Jahawareer, Torombositobiiniya, madax-xanuun, leukopenia, hurdo, xummad iyo madax wareer ayaa sidoo kale laga yaabaa inuu dhaco iyada oo sababtu tahay qaadashada kaniiniga, "tamoxin". Dhibaatooyinka ay keento waxaa ka mid ah, iyo khatarta ah ee dhiig-bax, makaanka, gubasho iyo cuncun ee xubnaha taranka, burooyinka fibrosis, urtikaria, dermatitis iyo bronchospasm. Ka sokow waxay noqon kartaa hoos u fiirsanayo in awoodba, dheecaanka hoosta haweenka, finan maqaarka ah iyo casaan.