Hepatocellular carcinoma beerka: Cilad, Calaamadaha iyo Daaweynta

kansarka Primary cudurada beerka waa dhif iyo naadir. Guud ahaan kansarka qanjirka 'prostate' waa sare, waa xadka-. The burooyinka beerka hoose la xidhiidha carcinoma holangio- iyo hepatocellular. kansarka Kuwani qaadi karaan labada raga iyo haweenka (dhif) ka mid ah. In carruurta, burooyinkaan yihiin ku dhowaad marnaba ka dhacaan. In bukaanka dhallinyarada ah waxaa laga yaabaa in la horumariyo kansarka beerka, oo ka soo jeeda unugyada SNMna - hepatoblastoma. cudurada Tani waa dhif. Ku dhowaad dhammaan hoose burooyinka beerka waxaa loo arkaa in ay dagaal badan. Waxay ku jirta kaalinta 5aad ee dhimashada in qaab-dhismeedka heley kansarka. Hadda, waxaan raadinaya hab cusub si looga hortago kansarka beerka. horumarka Great gaadhay daahfurka oo lala beegsaday therapy difaaca.

Description of hepatocellular carcinoma

hepatocellular carcinoma - kansarka ka mid ah unugyada beerka bandhigi atypia ah. In la barbardhigo heley kale aasaasiga ah oncological ee jirka, kaasu waa kan ugu baahday. buro waxaa kaloo loo yaqaan carcinoma cell cagaarshowga. In inta jeer ee hepatocellular carcinoma nin oo ka mid ah 5-tii ugu weyn ee dunida. buro Tani waa sii badan yahay waddamada horumariyo. Waxaa loola jeedaa in kansarka daran oo si degdeg ah horumar iyo inta badan lagu dhinto. Ma ahan oo kaliya ogaado goor dambe ee cudurka, laakiin sidoo kale in ay colaad iyo awoodda ay u metastasize in xubnaha kale. Tan waxa u sabab perfusion beerka.

Dhammaan noocyada kala duwan ee kansarka ku qoran Qoondaynta Caalamiga ah ee Cudurada (ICD). Sida cudurada kale ee kansarka, waxa ay leedahay ay code gaar ah u gaar ah, iyo hepatocellular carcinoma. ICD-10 waxaa laga isticmaalaa dalal dhan dunida. In soocidda cudurka ayaa S22.0 code a, taas oo macnaheedu yahay "carcinoma unugyada beerka." Inta badan, cudurada ay taasi dhacdo ka dhanka ah asalka ah oo ah xaaladaha raaga, sarkhaansan arrimood loo kasin.

Sababaha carcinoma beerka

Sida la og yahay, etiology ee burooyinka halista ah oo aan weli la bartay. Si kastaba ha ahaatee, saynisyahano ayaa muddo dheer ka soo helay oo factors cadhaysiinina horumarinta buro. No marka laga reebo iyo carcinoma cell cagaarshowga. Si aad u soo saamaynta soo socda:

1. sidayaal muddada dheer ah fayrasyada qaarkood. Waxaa la rumeysan yahay in heley sida cagaarshowga B ee joogtada ah iyo C, ay kordhiyaan halista ah ee soo koraya carcinoma cagaarshowga in ka badan 100 jeer. Waxaa intaa dheer, cudurada inta badan waa astaamo. Sidaa darteed, si loo yareeyo halista ah ee kansarka waa in la xilliyo gaar deeqdo dhiigga on fayrasyada hepatitis.
2. cirrhosis beerka ee etiology kasta. Bedelka of hepatocytes in nudaha connective badanaa dhacaa sabab u ah cudurka viral chronic, qaadashada khamriga iyo daroogada.
3. Cunista cunto hodan ku aflatoxin.
4. cabista hidde cudurka.
5. Admission daroogada hepatotoxic.

Haddii aan ka horjoogsanaya in arrimaha-qaabo ku qoran, halista hepatocellular carcinoma waa ay yar tahay. Si kastaba ha ahaatee, mid ka mid ma aha difaaca ka imaanaya burada this. Sida cudurada kale ee kansarka, waxay keeni kartaa ka-gaadhista ionizing shucaaca, sigaarka, nafaqo xumo, stress, iyo wixii la mid ah. D.

pathogenesis ee hepatocellular carcinoma

Sidaas darteed, caabuq chronic unugyada beerka caadiga ah bilaabaan inay u beddesho galay xubno buro. Maxaa sax ah u keenaysaa in ay la aqoon. Sababo la xiriira tallaabada of virus unugyada beerka waa kacsada, jidhka noqdo edematous, iyo xanuun badan. permeability korodhka vascular, ay u noqdaan kuwo ka buuxa dilaa ah. Sidaas awgeed, beerka waxaa loo kala dhantaalan. ka xaqiiqda ah in jidhka baabbi'in Qurub viral reebo, waxa ay saamayn ku yeelan waxyaabaha kale ee waxyeelada ka iman cuntada. Waxaas oo dhan waxay keenaysaa in isbadal unugyada. yaruna ku koraa in size, ka cytoplasm iyo organelles kale waxaa lagu wareejiyay dacallada ka. Ka dib markii in, gacanta uu bilaabo inuu kala qaybin sigan. Waxaa helo hannaanka ah nuclei, dheef hepatocyte in xadgudbay. In gacanta, burada bilaabaa inuu synthesize borotiinada in si degdeg ah ku fidaa dhiigga. Sayidka xidhan Hepatitis C iyo hepatocellular Carcinoma.

Waa in la xusuusnaado in ay tahay cudur fayras ku dhowaad mar walba ay cirrhosis of beerka ama kansarka. Xaaladaha intooda badan, waxaa hore u ogaadaa marka kac dhibaatooyin. waa magac kale oo hepatitis C - "gacankudhiigle, oo jilicsan". Tan waxa u sabab maqnaanshaha dhamaystiran oo daliilka kiliinikada ee cudurka sanado badan, iyo dhimashada dhaw iyada oo sababtu tahay joojinta hawlaha beerka.

Qoondaynta oo ah carcinomas hepatocellular

beerka hepatocellular carcinoma u qaybsan yahay dhawr foom oo lagu daawayn iyo morphological. Intaa waxaa dheer, burada lagu tilmaamay inay si waafaqsan heerka horumarka iyo heerka darnaanta. Iyada oo ku xidhan sawirka Guntin ah sheybaarada go'doonsan, weyn iyo foomamka waajihi ah kansarka beerka. Waxaa loo tixgeliyaa ah noocyada gooni ah hepatocellular carcinoma fibrolamellar. Sida laga soo xigtay sawirka caafimaad oo jira 6 nooc oo carcinoma unugyada beerka. Ka mid ah iyaga,

1. Doorashadan Gepatomegalichesky.
2. foomka Icteric.
3. muuqashadii xummada ah kansarka beerka.
4. foomka ascites.
5. Doorashadan caloosha Ba'an.
6. kansarka beerka xadka-.

Inta badan waxaa jira isku-dar ah dhowr Lahjadaha kiliinikada. Kansarka beerka-cell Stage ku xiran tahay cabbirka burada iyo baahsanaanta ee qanjidhada dhow iyo xubnaha kale.

hepatocellular carcinoma, calaamadaha

Calaamadaha ku xiran qaab caafimaad ee carcinoma. Xaaladaha intooda badan, marxaladaha hore ee kansarka leedahay wax calaamado ah. Intaa waxaa dheer, cudurka waa ay adag tahay sabab u tahay xaqiiqda ah in calaamadaha burada eg sawirka caafimaad ee cudurrada kale ee beerka (hepatitis chronic, cirrhosis). By daliilka kansarka goor dambe ka mid ah qandho-fasalka yar yahay, rabitaanka cuntada oo luma, daciifnimo, Lymphadenopathy, miisaanka oo yaraada. Marka foomka gepatomegalicheskoy of carcinoma arkay kor ugu kaceen beerka, xanuun hypochondrium saxda ah. Mid ka mid ah saddex-meelood meel dadka bukaanka ah waxay leeyihiin Lahjadaha joonis of cudurada. Waxay leedahay saadaal miskiin ah. Cagaarshow dhacdaa Marxaladda koowaad ama labaad ee burada.

Intaa waxaa dheer, bukaan ka cawdaan xanuun iyo cuncun. Marka foomka xummada calaamadeeyay koror joogto ah heerkulka jirka, dareenka xanuun xun ee caloosha sare. Ascites u muuqataa in marxaladaha sare ee kansarka, buro waxaa ku weheliyay astaamaha caadiga ah ee loo eedsaday. In ka yar caadiga ah qaab caloosha ba'an. Waxaa lagu gartaa xanuun aad u daran, kacsanaanta muruq abdominals. Xulashada for hepatocellular carcinoma xadka- heysatay by calaamadaha xubnaha kale. iyaga ka mid ah - lafaha, sambabada, mindhicirrada.

Foomamka Morphological of carcinoma beerka

burooyinka foomka fataahadda qarsan soo socda:

1. hepatocellular carcinoma u ballaaran. Waxay qaadataa qeybta dhan ama xuubka beerka. Marka cut uu leeyahay xuduud cad. Sidoo kale iyo Axdigu u yar (satalayt) joogo gudahood site burada noqon kartaa. Mid ka mid ah noocyo ka mid ah kansarka beerka weyn waxaa loo arkaa inay nooc ka mid ah caloosha. Ugu site burada la ogaado qeybaha kala, gudaha taas oo ay jirto dareere ah brown. derbiga saabka qaro weyn oo siman.
2. hepatocellular carcinoma nodular. Lagu gartaa hannaanka ah Axdigu buro ku taala oo dhan dusha jirka parenchyma ah.
3. carcinoma Beerka waajihi. Inta badan waxa uu yeeshay ku saabsan asalka ah cirrhosis. parenchyma oo dhan ka kooban oo ka mid ah xubno ka mid ah unugyo iyo unugyo aan caadi ahayn.

carcinoma Fibrolamellar ka kooban yahay hal ama ka badan oo goobo yar. Xaaladaha intooda badan waxaa ku kooban in xuubka bidix ee beerka. Color buro - huruud ah ama cagaar ah. nooc kale oo kala duwan waxaa loo arkaa in la soo maaxanaysay (yar), carcinoma cell cagaarshowga. Waxaa lagu gartaa saadaal wanaagsan iyo koritaanka gaabis ah, size buro ka yar tahay 5 cm dhexroor.

Cilad-beerka hepatocellular carcinoma

Waxaa lagama maarmaan ah in la sameeyo noocyo kala duwan oo baaritaan ka hor si ay u aqoonsadaan cudurada sida hepatocellular carcinoma. Pathology Baaritaanka wuxuu ka kooban yahay dhowr marxaladood. First, dhakhtar ah wuu maqlaa dhammaan cabashooyinka bukaanka iyo waxay baaraan. fiiro gaar ah waxaa la siiyaa maqaarka (midabka, raschosov joogaan, hemorrhage), qanjirada, taataabasho beerka. In kansarka ee jidhka ayaa dusha ku socoto, texture cufan, calaamadeeyay danqasho. Intaas ka dib, tiro ka mid ah sahan. Ka mid ah iyaga,

1. KLA, chemistry dhiigga.
2. Go'aaminta heerka calamado gaar ah - Alfa-fetoprotein.
3. Ultrasonography ee caloosha.
4. raajito loogu xisaabiyaa.
5. Studies weelashii cagaarshowga. Kuwaas waxaa ka mid angio iyo portogepatografiyu.

Cilad ku salaysan yahay natiijooyinka cytological iyo histological. Si ay u qabtaan cilmiga kuwaas, oofiyey biopsy xubin.

hepatocellular carcinoma beerka, daaweynta cudurrada

istaraatijiyad daaweynta Xulashada ku xiran qaab morphological iyo cabirka burada, iyo stage of habka kansarka. In marxaladaha hore ee qalliinka kansarka waxaa loo sameeyaa, rajo gelin qanjira thyroid, chemotherapy. In burooyinka waajihi sameeyaa embolization ee halbowlaha cagaarshowga. Tani waxay ka caawisaa si ay u yareeyaan koritaanka burooyinka iyo xaddido geedi socodka. hepatocellular carcinoma beerka ma aha xasaasi u ah daaweynta shucaaca. Intaa waxaa dheer, waa dhif kasteba si chemotherapy,% bukaannada kaliya 15-20 saamayn ku meel gaadh ah positive. Mid ka mid ah jidkiisu waa badalida beerka. In wadamada horumaray, habkan waa mid ku baahsan. Badalida ah xubin deeq ah waxaa lagu sameeyaa oo keliya in marxaladaha hore ee kansarka. In joogitaanka metastases fog waxaa loo arkaa sida kaliya ee lagu daweeyo therapy astaamaha. Waxaa ka mid ah daryeelka palliative (daryeelka bukaanka, teraabiyada cilminafsiga) iyo suuxinta.

daaweynta qalliinka kansarka beerka

qalliin waxaa lagu fuliyaa dhammaan bukaanka waxaa laga helaa "hepatocellular carcinoma". Daaweyntu waxay ka mid resection beerka gudahood gobolka jidh (qeybta jirka badh share). Haddii unit yar oo cabbirkooda sameeyaa ay enucleation aspirator gaar ah. Hab kale oo waa qaliin - embolization a KORONARKAR ee halbowlaha cagaarshowga.

Sida ugu haboon ee ay tahay in xubin xubin ama qayb dhanba. unugyada beerka waxa uu leeyahay awood u leh inay cusboonaysiiyaan. Tani waxay keeni kartaa in bukaan-socodka dib u soo kabashada buuxda.

therapy Drug ka dhanka ah hepatocellular carcinoma

Waxa intaa dheer in daawooyinka kiimikada, si firfircoon loo isticmaalaa koox cusub pharmacological daroogada - celiyeyaasha of kinases protein. Waxay saamayn waa in la yareeyo kororka ee unugyada burada. Inkastoo dhibaatooyinka badan, daawooyinka, kuwaas waa kuwo wax ku ool ah. Tusaale ka mid ah daroogada ee group tani waa daroogada "Nexavar".

saadaasha ee hepatocellular carcinoma

Mid ka mid ah burooyinka halista ah dagaal-mareenka caloosha iyo mindhicirka waxaa loo arkaa hepatocellular carcinoma beerka. saadaasha ee burada this kiisaska intooda badan allifey. Heerka Sare ee badbaadada 5-sano ayaa lagu arkay oo keliya at formation tirada yar qalliin ama xubin badalida beerka ka dib. Inta badan waxaa jira xoogeystay ka mid ah buro iyo metastasis degdeg ah. jirka howlgal Joojinta waa loo dhintaa.

Ka hortagga hepatocellular carcinoma

tallaabooyinka ka hortagga waxaa ka mid ah sahanka sanadle ah oo ku saabsan fayraska hepatitis, diidmada ah ee daroogada iyo khamriga. Waxaa haboon in la xasuusnaado in caabuq ku dhaca beerka laga heli karaa iyada oo sababtu tahay manipulations sida daaweynta ilkaha iyo qurux, in dhiig lagu shubo.