"Gabapentin" iyo khamriga, dib u eegista. "Gabapentin": tilmaamaha loo isticmaalo, Kurtumm bukaanka iyo dhakhaatiirta

Muddo markii la joogaba, casiraad muruq dhibaato dad badan. Si kastaba ha ahaatee, dad yar ka fikir sababta dalalka sida guud ahaan kac.

Sida laga soo xigtay casri ah, qalal noqon kartaa kala duwan: guud (tonic, clonic, tonic clonic-iyo myoclonic) iyo qayb ahaan (fudud oo adag). daroogada loo isticmaalo in lagu daaweeyo qalal ee la soo dhaafay sida "Gabapentin". Tilmaamaha loogu isticmaalo, dib u eegista iyo sababo daroogada loo soo bandhigi doono wax yar ka dib.

Waa in si deg deg ah in la ogaadaa in, waayo, suuxdin qayb ahaan lagu gartaa maqnaanshaha miyirka oo luma. xaalad dhif noocan oo kale ah. Waxay u muuqdaan nooca qalal clonic lug ah murqaha gacmaha, lugaha iyo wajiga.

Curiska, sharaxaad, wax soo saarka baakadaha iyo inta ay ka kooban

iibin medicament "Gabapentin" In wixii foomka? Kurtumm sheegaan in dawadan waxa laga iibsan karaa farmashiyaha oo ah qaab kaabsoosha gelatin adag oo dhar cadcad. waxyaabaha ay yihiin huruud ah ama caddaan daroogada budo.

Walaxda firfircoon ee wakiilka tani waa gabapentin. Sidoo kale, waxaa ka mid ah walax kale oo dheeraad ah oo ah qaab noqde sodium carboxymethyl, milmahayn calcium iyo cellulose mikrokristallin. Sida kaabsulka ah, ay ku jiraan gelatin iyo titanium dioxide.

In xirmo iibin daroogada "Gabapentin"? dib u eegista Consumer ayaa sheegaya in on gadhi farmashiyaha daawada waxaa laga heli karaa baakad kartoonada, kuwaas oo kaalinta labada kaabsoosha daasadaha polymeric ama dusha of unugyada.

Mabda'a garoomada ka mid ah daroogada

Sidee daroogada "Gabapentin"? Tilmaamaha (dib u eegista daawada waxaa lagu soo bandhigay dhamaadka maqaalka) ayaa sheegay in daroogada ay qaab-dhismeedka aad uula mid tahay gamma-aminobutyric acid neurotransmitter ah (reer Gebacna soo gaabiyo). Si kastaba ha ahaatee, waxaa la ogaadaa in mabda 'ee ay tallaabo aasaas ahaan waa kala duwan oo ka soo daawooyinka kale ee la macaamilaan reer Gebacna-receptors (tus, valproate, barbiturates, benzodiazepines, reer Gebacna transaminase inhibitors, reer Gebacna reuptake inhibitors, agonister reer Gebacna iyo prodrugs ee reer Gebacna).

daroogada viewed laha guryaha reer Gebacna-nayaa iyo wax saameyn ah kuma soo qabashada iyo dheef ah ee reer Gebacna. khubaro Research waxay muujiyeen in qayb firfircoon ee wakiilka by qabanaya si α2-δ-subunit ee channels calcium danab ku tiirsan, aad bay u yareeyo socodka udhigo calcium, taas oo ka ciyaaraan door muhiim ah ee bilawga ah ee xanuun neuropathic.

Maqaallo daroogada anticonvulsant

Waa maxay guryaha kale waxaa hantiyeen by daroogada "Gabapentin"? Reviews of dhakhaatiirta waxa ay sheegayaan in aad waxtar u leh xanuunka neuropathic. daroogada Tani waxa ay yaraynaysaa dhimashada neuronal glutamate ku tiirsan, sii kordhaya Avv reer Gebacna, iyo sidoo kale habka ah xakamaynta kooxaha sii daayo iyo monoamine neurotransmitter.

Waxaan ma dhihi karo in ay isugu soo urureen Caafimaad ahaan la xiriira daroogada "Gabapentin" ma xidho receptors daroogooyinka kale (ama neurotransmitters), oo ay ku jiraan receptors Gibecaah oo GABAB, iyo glutamate, receptors Benzodiazepin, glycine, iyo N-methyl-D- aspartate.

Si ka duwan "carbamazepine" iyo "phenytoin", loo arkaa medicament uusan ula falgalaan channels sodium. Diyaarinta "gabapentin" qayb ahaan attenuates saamaynta agonist receptor glutamate sida N-methyl-D-aspartate. Waxaa intaa dheer, waxay si weyn u yaraynaysaa sii daayo neurotransmitters monoamine.

The guryaha ogeed daroogada

Waa maxay soo jireenka ah kaabsoosha oo xuduudaheedu ogeed "Gabapentin"? Kurtumm ma noqon doonto in ay ka jawaabaan su'aashan awoodaan. Si aad u heli, waxaad yeelan doontaa in ay soo jeedin in ay khibrad iyo xirfad ama tilmaamaha ku lifaaqan.

Sida laga soo xigtay dambaysta ah, bioavailability ee ku yidhi daroogada ma aha saamiyeed si ay qiyaasta la ansixiyay. Marka xaddiga daroogada waa la dhimay.

Marka la helo medicament galay uu fiirsashada plasma badnaan arkay ka dib markii 3 h. bioavailability The waadaxa ah ee daroogada ee kaabsoosha qiyaastii waa 60%. Cuntada, oo ay ku jiraan aad u buuran, saameyn ah kuma laha ee kinetics of daroogada.

Noqoshada "Gabapentin" dhiigga qofka bukaanka ah waa la fuliyay by model toosan. wakhti badhkiis-nolosha waa ka madax banaan qiyaasta iyo waa qiyaastii 5-7 saacadood.

The guryaha ogeed daroogada ma ay isbeddelayso xittaa marka ay si joogta ah waxaa laga codsadaa. fiirsashada ee daroogada ah ee dhiigga la sii saadaalin karin ku salaysan natiijooyinka ay dose hal.

medicament The "Gabapentin" ku ool ah ma u xidhi borotiinka plasma (in ka yar 3%). Waxaa la soo bandhigay qaab beddelin by kelyaha.

Metabolize daawada aan qaawan. Waxaa intaa dheer, waxa aanu u abaari ensaymes oxidative cagaarshowga, taas oo ay ku lug-shiid ee daroogooyinka kale.

ansixin ee wakiilka ka dhiigga hoos dadka waayeelka ah iyo dadka qaba shaqada kelyaha dhantaalan.

Diyaarinta "gabapentin" laga saaro jidhka ka by kelyaha.

Tilmaamayaasha si aad u hesho daawo

In waxa cudurrada aan ku fekereyno waa daroogada gaar ahaan wax ku ool ah? Maxay yihiin dad leh oo ku saabsan jawaab-celinta this?

"Gabapentin" teedu wanaagsan laftiisa in:

• xanuun neuropathic in bukaanada qaangaarka ah (18 sanno iyo ka weyn);
• monotherapy ama sida daroogada ah kaabaha lagu daaweyn jiray suuxdin qayb ahaan, oo ay la socdaan guud sare ee dadka waaweyn iyo dhalinyarada 12 sano ka yar.

Sababo in la helo daawo

Waa maxay daawada sababo leeyahay "Gabapentin"? Reviews of codsiga sheegaan in uu leeyahay saamayn xun ku jidhka, haddii dawada la aqbalay at:

• diidmo in kasta oo ah walaxda;
• gariir Qayb da'doodu ka yar tahay 12 sano.

daryeel gaar ah waa hab loogu kelyaha.

Sidee baan u qaataa daawada "Gabapentin"?

Reviews (neuralgia daawaynta this ka caawisaa aad u wanaagsan) Dawladdu in daroogada waa in la maamulo kaliya dhakhtar khibrad leh, ka dib markii cudurka saxda ah.

kaabsoosha gelatin afka laga qaato oo ay wax liqidda oo dhan, in ay qaab. Daawada waa in loo eegin hadhuudhka ah ayuu ku baabba'saday, hoos u maydhay dareere badan. Haddii aad u baahan tahay si loo yareeyo qiyaasta, burin ama bedeli analoogga daroogada oo dhan, markaas waa in la sameeyo si tartiib tartiib ah in ka badan toddobaadkii.

Daaweynta xanuun neuropathic ee dadka waaweyn

Sida in this falalka gobolka daawo loo arkaa? Maxaa qof ayaa ku yidhi ku saabsan dib u eegista caafimaadka? "Gabapentin" aad wax ku ool ah u muuqato xanuunka neuropathic. In loola dhaqmo xaaladda dose maalin walba sida bilowga ah waa in ay ahaataa 900 mg. lacagta ayaa sheegay in waxa loo qaybiyaa saddex qaybood. Haddii loo baahdo, ee qiyaasta waxaa si tartiib ah kor u kacay in ugu badnaan (i.e., ilaa 3600 mg maalintii).

qalal qayb

Sidee baan u qaataa daawada "gabapentin" in cudurkan? Reviews ayaa sheegay in qalab lagu meelaynayaa karo ma aha oo kaliya in ay dadka waaweyn, laakiin dhallinyarada ka 12 sano.

Qiyaasta waxtar u leh qalal qayb ahaan loo arkaa 900-2400 mg maalintii. Daaweynta cudurkan bilaabi kartaa 300 mg ah ee daawada saddex jeer maalintii. Ka dibna waxa dose maalin walba in la kordhiyo in 900 mg, iyo in ka badan oo ilaa 2400 mg maalintii (kala qaybiyey saddex qiyaasood oo loo siman yahay).

bareeg waqtiga u dhexeeya qiyaasood oo ah daroogada ee ay soo dhaweynta xaafuun waa in aanay noqon ka badan 12 saacadood (si looga fogaado in dib suuxitaan).

waxyeellooyin

Maxaa dhibaato ku dhici kara bukaanlayda qaadato anticonvulsant? Maxaa qof ayaa ku yidhi ku saabsan dib u eegista macaamiisha this? "Gabapentin" ee lagu daaweeyo xanuunka neuropathic wuxuu sababi karaa:

• asthenia, dhaawaca shilka, xanuunka deegaamaynta kala duwan, dhabar xanuunka, caabuq, flu syndrome, madax-xanuun, miisaanka oo kordha, barar durugsan;
• khalkhal wiiqmin, ataxia, xusuus la'aan, hypoesthesia, wareer, dawakh, fikirka oo yaraada, hurdo, gariirka,
• caloosha oo, yaaqyaaqsi, shuban, matag, afka oo qalala, dyspepsia, lalabo, calool xanuun,
• finan maqaarka ah,
• neefta oo ku qabata, dhuun xanuun,
• amblyopia.

In lagu daaweyn jiray suuxdin qayb ahaan, daawada ku kordhinaya muuqashada:

• dhabar xanuunka, daal, qandho, madax-xanuun, caabuq fayras, barar durugsan, miisaanka oo kordha, daal, qidmeyntiibulshada, barar wajiga,
• caloosha oo, cudurada ilkaha, shuban, saxarada, rabitaanka cuntada oo kordhay, qallayl ee cunaha ama afka, lalabo ama matag, calool xanuun, dibiro, anorexia, yiridka,
• calaamad of vasodilation ama hypertension,
• leukopenia, purpura;
• jab, myalgia iyo arthralgia;
• xusuus la'aan, ataxia, wareer, incoordination, murugada, dysarthria, lability dareenka, hurdo la'aan, isku yaacsanaan, nystagmus, hurdo, fikirka aan caadi ahayn, gariirka, shimbirka muruqa, dawakhaad, hyperkinesia; faa'iidada, daciifaan ama maqnaanshaha of hummaag, walaaca, paresthesia, cadaawad,
• qaadmay, finan, cuncun maqaarka, finan maqaarka ah,
• qufac, pharyngitis, rhinitt, pneumonia,
• amblyopia, diplopia, aragga indhaha oo isku darsamay;
• cudurada kaadi-mareenka, kacsi la'aanta.

xaaladood oo badinta

Maxay yihiin calaamadaha badinta keeni karaa medicament? Maxaa ku saabsan odhan dib u eegista ah? "Gabapentin" xad dhaafka sababa double aragga, dawakhaad, hurdo, hadalka oo yaraada, feejignaan xumo iyo shuban.

Si aad u baabi'iyo dalalka sida therapy astaamaha, iyo sidoo kale caloosha dhibanaha maydhay oo u siin dhuxusha firfircoonaan.

Bukaanka qaba la'aan kelyaha ee daran, kelyaha lagu muujiyay.

Drug "Gabapentin" iyo khamriga

takhasusay Reviews sheegaan in tayada oo ka mid ah daawooyinka loo arkaa waa mid aad u sarreeya. Laakiin waxaa kaliya ay dhacdo in muddada ay codsiga bukaanka waxaa gebi ahaanba ka baxay isticmaalka cabitaanka khamriga.

Haddii daawada lagu daro khamriga, bukaanka si weyn u sii dari kara falcelin caksi ah ka nidaamka dhexe ee neerfaha (maskax hurudda, ataxia, iwm).

isdhexgalka daroogada

Drug "gabapentin" in neuroscience, dib u eegista ah oo ka sii badan yihiin wanaagsan, lagu ma dari karaa daawooyinka oo dhan.

Sida laga soo xigtay tilmaamaha, laabjeexa yareeyo bioavailability ee daroogada.

daroogada Myelotoxicity kordhin kaabsoosha haematotoxicity "Gabapentin".

Marka lagu daro morphine pharmacokinetics ay innaba ma beddelmin. Si kastaba ha ahaatee, isu-gaynta sida waa in had iyo jeer la socon dhinaca reactions suurto galka ah ee habka dareemayaasha jirka.

medicament viewed isku mar la qaadan karaa daawooyin antiepileptic (tus, "pentobarbital", "carbamazepine", "phenytoin" iyo valproic acid) iyo piller. Xaaladdan oo kale, ma beddeli kinetics ah.

talooyin gaar ah

In kasta oo xaqiiqda ah in syndrome bixitaanka la dhacdo ee qalal ee daaweynta ee "gabapentin" lama calaamadeeyay by joojiyo kadis ah ku daawaynta daawooyinka antiepileptic in dadka qaba qalal qayb weli ka cadhaysiinina kartaa gariir xoog leh.

daawo viewed ma aha hab wax ku ool ah si loola dagaallamo la qalalka maqan.

Dadka u baahan daaweynta adag la morphine, waxaa laga yaabaa in u baahan tahay qaadasho kordhaysa oo ah "gabapentin". Xaaladdan oo kale, loo hubiyo in la socodka joogtada ah ee bukaanka ah ee horumarka ah ee la qabsi. At daawooyinka ay aqoonsashada waa qiyaas la filan la dhimay.

Marka lagu daro "gabapentin" kale daawooyinka anticonvulsant ayaa la soo sheegay natiijada been wanaagsan in go'aan ka soo baxay borotiin laga helo kaadida isticmaalaya strips imtixaanka Ames N-Multistix ki Moon. Marka tan la eego, waxbarashada sida ku talinaynaa isticmaalka hab roobab gaar ah by sulfosalicylic acid.

xirfadlayaasha Reviews iyo macaamiisha

dib u eegista Inta badan dhakhaatiirta iyo bukaanka oo ku saabsan "Gabapentin" diyaarinta fiican. wararka waxay tusayaan in daroogada ku ool ah ay ula qabsadaan hawsha. Si kastaba ha ahaatee, marka lagu daro khamriga inta badan waxay yeeshaan dhibaato daran in habka dareemayaasha jirka.

Waa wax aan macquul ma ah in la ogaado xaqiiqada ah in bixitaanka kadis ah daroogada waxay keeni kartaa miyir bukaanka uu helaba, feejignaan xumo iyo niyadda xun.

Dad badan ayaa sheegay in qaadashada ee taasi ka dhigan tahay in ay qabaan murugada iyo fikradaha isdilka. Sidoo kale, daawo inta badan sababa horumarinta pankreatit ba'an.

Khubarada ku talinaynaa in daaweyn daroogada "Gabapentin" oo kaliya iyada oo ay kormeerayaan dhakhtar kan kara inuu si dhakhso ah ula qabsadaan mudada ku-daweynta sida loogu baahan yahay waxay noqon doontaa.