Drug 'Zocor', tilmaamaha loo isticmaalo, xogta cilmi-caafimaad

"Zocor" - daawo la xiriira daroogo group hypolipidemic kiliinikada iyo pharmacological. The dejinta firfircoon wakiilka "Zocor" - simvastin, hal kiniin ku jiri kara 10,20, iyo 40 mg, iyo sidoo kale kaabayaal: ascorbic oo qaarna, butylhydroxyanisole, Rusheyn kartaa, milmahayn magnesium iyo kuwa kale.

'Zocor' waa aad u wax ku ool ah, oo iska xanaajin guud yareynta kolesteroolka ee jirka. Tani waxay si gaar ah muhiim in hyperlipidemia oo isku darsan, maxaa yeelay cudurka ee ay content korodhka waxaa loo arkaa arrin halis ah. In ka badan mudo ah 2 todobaad waxaa suurtagal ah si ay u gaaraan a dhaqdhaqaaqa wanaagsan dareemi, saamaynta ku daweynta lagu hayaa at heerka ugu badnaan 4 - 6 toddobaad. kolestaroolka waxaa ku soo laabtay goob hore marka aad joojiso daaweynta la 'Zocor', diiwaanka waxaa ku qoran qaar ka mid ah cilmi baaris ku macluumaadka daawooyinka.

Monitoring bukaannada ku jira xaddi Man saabsan 4.5 kun. Waxaa laga sameeyey for 5.4 sano. At oo dhan waxbarasho arkay kolestaroolka (mg / dl.), 212 - 309. Reception "Zocor" 30% khatarta hoos u dhimashada, tirada Wadnaxanuun myocardial by 37% (xaaladood oo la xaqiijiyay in goobaha bukaan eegida), 42% - dhimashada CHD. In a 37-bukaan ka mid ah 100 waxaa jiray uma baahna qaliin caadi ah socodka dhiigga wadnaha.

In UK, 5.5 sano waraystay bukaanka (20536 oo qof), kuwaas oo arkay ama saadaaliyay CHD. In saddex meelood oo meel daraasadda halista ah ee stroke iyo wadne waxaa hoos u dhigay ugu yaraan. Iyadoo in, heerka kolestaroolka hore, sinnaan daaweynta ku-daweynta, jinsiga iyo da'da dadka bukaanka ah ma saamayn ku oolnimada of qaadashada daroogada "Zocor". Tilmaamaha loogu isticmaalo qeexayaa si faahfaahsan pharmacokinetics ay, ka hor intaadan gelin dhiiga waxaa la nuugo ka soo mareenka caloosha iyo mindhicirka. Waxaa la soo experimentally muujiyay raasamaal simvastina sare ee beerka iyo xubnaha kale ee fiirsashada laga helay xaddi badan oo yar yar, walaxda firfircoon ka qayib bile ah.

cudurka ischaemic qalbiga ku waa calaamad muujinaysa ugu muhiimsan ee daroogada "Zocor", tilmaamaha loo isticmaalo waxaa loola jeedaa isticmaalka qaar ka mid ah gool uu:

- qiyaas ka hortagga wadne;

- hoos u socodka ah ee atherosclerosis coronary;

- xasilinta ee dhimista halista stroke, stroke.

Marka Qolol heerarka kolesteroolka daroogada "Zocor" kordhinayaan in ay hoos iyo waxtardarradoodu ee cuntada ku-daweynta, iyo sidoo kale tallaabooyin kale oo aan pharmacological sida marka hypercholesterolemia hormaray arrin halis ah, waxaa haboon in la magacaabo lekartsvennogo hab.

In beerka marxaladda failure ba'an loola jeedaa contraindication ee maamulka daroogada "Zocor". Tilmaamaha loogu isticmaalo waxaa sidoo kale aan lagu talinayaa in la isticmaalo daroogada inta ay uurka leedahay ama naas nuujinta, iyo sidoo kale ogaanshaha diidmo in daroogada.

"Zocor" sababa waxyeelo qaar ka mid ah nidaamka dheefshiidka. Iyadoo qaadashada daroogada "Zocor" ah, dhibcood hadal si calool suurto gal ah, calool xanuun ah, waxaa jira macluumaad ku saabsan kiis oo hepatitis, ganaca, joonis.

Dhibaatooyinka ay keento arkay marka la eego habka dhexe ee dareemayaasha jirka, tani xanuun murqaha, dawakhaad, neuropathy durugsan.

Marar dhif ah, laakiin dareen diidmo oo xasaasiyadeed dhacaan sida anjioedema, vaskulitis, volchanochnopodobnogo syndrome, arthritis, kor u ESR, qandho, dyspnea, eosinophilia.

Xaaladaha ah qiyaasta xad dhaafka laga helay daliilka dhinaca xun loo arkaa qaatay dose ugu badnaan 450 mg.

Store daroogada "Zocor" talinayaa in t max 30 digrii, xataa gaadhista ku meel gaar ah oo ku saabsan t 50 darajo waa in laga fogaadaa.