Diabetes Phosphate: sababaha, calaamadaha, cudurka, daaweynta

In dunida maanta ku dhowaad dhammaan waalidiinta waa ay ka warqabaan cudurkan, sida rickets. On baahida loo qabo ka hortagga cudurka this ka hortagtaa dhakhtarka ilmaha kasta bilaha ugu horeeya ee nolosha ilmaha. Rickets loola jeedaa cudurada helay soo koraya ay sabab u tahay Cholecalciferol ku filnayn - maaddo loo yaqaan vitamin D.

Si kastaba ha ahaatee, mararka qaarkood in caruurta aadka u yaryar leedahay calaamadaha cudurka, inkastoo ay u hogaansanaanta in ay tallaabooyin ka hortag ah. In kiiska noocan oo kale ah waa in la tuhunsan yahay cudur sida sonkorowga phosphate. Si ka duwan rickets, cudurka la xidhiidha heley hidaha. Sidaa darteed, waa cudur daran oo u baahan daaweyn adag dheer.

Waa maxay diabetes phosphate ah?

Sidaas waa koox ka mid ah cudurada la xiriira hidda-shiid oo yaraada macdanta. In cudurada kale loo yaqaan rickets vitamin D-u adkaysta. Nooca badan ee cudurka macaanka phosphate ku dhacaa qiyaastii illaa 1 canug ka mid ah 20,000 carruur dhallaan ah. Cudurka ahaa ee ugu horeeyay ku tilmaamay in 1937. Later waxaa soo baxay in ay jiraan qaabab kale oo aan caadi ahayn hidaha. Inta badan, macaanka phosphate la ogaado in carruurnimada hore. Waxaa soo jiidata dareenka qas waalidiinta wiiqmin iyo dhalanrog ee lafta.

Qaar ka mid ah cudurka waxaa weheliya xanuunada kale ee dheefshiidka. Mararka qaarkood cudurka waa astaamo iyo uun tilmaami karaa baarista shaybaarka. cudurka lagu tilmaamay inay la rickets helay, hypoparathyroidism iyo cilladaha kale hormoonada jidhka. Daaweynta waa in lagu daro da'da hore.

Sababaha cudurka

Sababta ugu weyn ee cudurka macaanka phosphate waa la jebiyey in qaab dhismeedka hidaha. Isbedelo ayaa la dhaxlay. Xambaarsan hiddo aan caadi ahayn waxay noqon karaan rag haween iyo. isbedel ayaa wuxuu ku dhacaa X-koromosoom ku xiran, kaas oo xukuma. Marar dhif ah, sonkorowga phosphate shruudo. Waxa uu yeesho ee burooyinka ee mesenchymal unugyada, aasaasay in utero. In cudurada tani waxaa la yiraahdaa "rickets oncogenic."

Cudurka waxaa loola jeedaa tubulopathy koox - cudurada of kelyaha. Maxaa yeelay, macdanta hoos loo nuugay ee tubule ku proximal, horumarinta deficiency ah fosfooraska ee jirka. Intaa waxaa dheer, soo dhibtay awoodda nuugid mindhicirka. Sidaas darteed, waxaa jira isbedel ku Halabuurka macdanta unugyada lafta ah. inta badan waxaa jira xadgudub ku ah shaqada osteoblast. Ragga mari hiddo pathologically doorsoon kaliya gabdhaha, iyo haweenka - oo reer labada jinsiba. Sida caadiga ah, wiilasha cudurka daran ka badan ee gabdhaha.

Qoondaynta of diabetes phosphate in carruurta

Waxa jira noocyo dhowr ah oo cudurka, kala duwan ee shuruudaha hidaha iyo caafimaadeed. Inta badan cudurka rickets hypophosphatemic X-lala, taas oo uu leeyahay qaab xukuma dhaxalka. Si kastaba ha ahaatee, waxaa jira noocyo kale oo ka mid ah cudurada. kala soocidda waxaa ka mid ah foomka soo socda ee cudurka:

1. diabetes phosphate X-lala nooca xukuma. Waxaa lagu gartaa isbeddel ah hiddo-PHEX, taas oo baaq endopeptidase ah. enzyme Tani waa ka masuul ah gaadiidka ee macdanta kala duwan iyada oo kelyaha iyo channels ra'iyi xiidmaha. Maxaa yeelay, habka this waxaa isbeddel hiddo caanuhu, siinta asaasmeen failure by udhigo phosphate ee jirka.
2. X-lala recessive. waxaa isbeddel CLCN5 lagu gartaa of hiddo ah in ey protein ah masuul ka ah hawlgalka channels ra'iyi chlorine. Sidaas darteed of iin ku carqaladeeyey gaadiid walxaha dhex xuub ah tubules kelyaha. Sidayaal of noocan ah cudurada noqon kartaa rag iyo dumar. Si kastaba ha ahaatee, cudurka dhacdaa keliya ee wiilasha.
3. hannaankii xukuma Autosomal of diabetes phosphate. Waxaa la xiriira isbeddel kaga dhacaa hidde ee koromosoom 12. Maxaa yeelay, osteoblasts iin bahal waa protein go'doon oo u ololeeysa wanaajiyey phosphate jidhka ka saarista. cudurradana waxa lagu gartaa khafiif ah, sida soo horjeeda qaab X-lala ku.
4. Autosomal recessive. Rare. Lagu gartaa DMP1 hiddo haleysan yahay waxa uu ku yaalaa ee koromosoom 4. Waxay baaq protein ah in mas'uul ka yahay horumarinta laftayda iyo dentin.
5. Autosomal recessive, Ulasocto sii daayo calcium kaadida. Baxdo sababtoo ah iin hiddo yaal koromosoom 9 iyo amarka reer binu channels kelyaha sodium ku tiirsan.

Waxa intaa dheer in noocyadan diabetes phosphate, waxaa jira noocyo kale oo ah cudurada. Noocyo Qaar ka mid ah cudurka aan la bartay ilaa haatan.

Farqiyada u dhexeeya rickets iyo diabetes phosphate

Rickets iyo diabetes phosphate in carruurta - tani ma aha wax isku mid ah ilaa xad ah, inkastoo sawirka caafimaad ee cudurka durba waa isku mid. faraqa u dhexeeya heley, kuwaas oo in ka etiology iyo farsamo ee horumarka. rickets caadiga ah - waa helay cudurka la xidhiidha la'aan ah Cholecalciferol. walax waxaa soo saaray oo dubka sarkhaansan yihiin qoraxda. dose Baarista ee vitamin D waxaa laga dhigay in ay qaataan on joogta ah maalin walba carruurta oo dhan laga bilaabo 1 bisha ilaa 3 sano, marka laga reebo xagaaga. Sababo la failure of Cholecalciferol rabshaysan tahay habka nuugista calcium. Sidaas darteed of horumarinta lahayo ku lafaha.

Si ka duwan macaanka phosphate waa in loola jeedaa in cudur lagu dhasho. Marka cudurada this rabshaysan tahay nuugista macdanta ee kelyaha, gaar ahaan - phosphates ah. Xaaladaha qaarkood, waxaa jira yaraanta calcium. Sababo la xiriira xadgudubyada Halabuurka macdanta ee heley unugyada lafta sida calaamadaha. Farqiga u dhaxeeya dhismi kartaa oo keliya ka dib markii cudurka shaybaarka.

rickets Hypophosphatemic carruurta: calaamadaha

Astaamaha cudurka waxa sida caadiga ah laga helay inta lagu guda jiro sanadka labaad ee nolosha. Marar dhif ah, waxaa jira rickets hypophosphatemic ee dhallaanka. Calaamadaha in lagu ogaan karaa in yaraantaadii - summer iyo addinka yaraynta muruqa ah. The daliilka ugu weyn ee lagu daawayn karo waa:

1. Lahayo ku kalagoysyada lugta.
2. O-qaabeeya dhaf oo ka mid ah jirka hoose.
3. dhimaal koritaanka carruurta - noqdo dareemi 1 sano ka dib.
4. Adkaanshaha carjawda curcurka iyo feedhii - "dugaagado riketis iyo kuul."
5. Xanuun lafihii ee miskaha iyo dhabarta.
6. Burburka of dhaldhalaalka iliga.

Inta badan cabashada ugu weyn ee waalidiinta waa in lugaha ilmaha waxay ku tashadeen. Iyadoo horumarka cudurka jiro meletariga lafaha - osteomalacia.

Cilad-macaanka phosphate iyo rickets

Si loo ogaado aan caadi ahayn, baadhitaan ah oo ka kooban lagmamaarmaanna u ah dhiig. Waxaa la xusay hypophosphatemia. heerka calcium kiisaska intooda badan caadi ah, oo mararka qaarkood - hoos. At height of rickets uu jiro korodh ah phosphatase xumadoodu. Marka X-rays shaaca ka qaaday osteoporosis iyo koritaanka lafaha xadgudub zone. In kaadida tilmaamay xaddi weyn oo phosphates. Mararka qaarkood waxaa jira calcium kaadida.

Daaweynta rickets iyo diabetes phosphate

Wixii lagu daaweyn jiray sonkorowga phosphate isticmaalo qaadasho badan oo Cholecalciferol. Xaaladaha qaarkood, muujisay calcium supplements. U hubso in aad isticmaasho dawooyinka ay ku jiraan fosfooraska. Si loo hagaajiyo xaaladda qoray vitamin iyo macdanta supplements. Kuwaas waxaa ka mid ah daroogada "Vitrum" "Duovit", "alifbeetada" iyo wixii la mid ah D..

Marka curvatures muujiyay lafaha muujiyay daaweynta dabiiciga ah, daaweynta jirka iyo qalliin. Waa inay kala tashadaan podiatrist ah.

tallaabooyin ka-hortag iyo saadaasha

Waayo, ka hortagga tallaabooyin ka mid ah baadhitaanka dhakhtarka carruurta iyo qalliinka, socod ee hawada cusub, magacaabidda vitamin D ka bishii kowaad ee nolosha. Haddii qoyska jiran of diabetes phosphate tahay in uu maro baaritaanka hidde in ilmaha caloosha ku utero. Saadaasha inta badan wanaagsan daaweynta waqtigii.