"Ademethionine": tilmaamaha loo isticmaalo, analogs, dib u eegista

Waa maxay ademetionine maalkii? Tilmaamaha isticmaalka diyaarinta, oo ay ku jiraan qayb ka ah in lagu tilmaami doonaa halkan. Waxa kale oo aanu kuu sheegi ku saabsan sida ay kukacayaan qalab la mid ah in dadka isticmaala leh oo ku saabsan, iyo wixii la mid ah.

Form of daroogada, ay sharaxaad

In waxa foomka waa daroogada la heli karo "Geptral" (INN "Ademethionine")? Tilmaamaha Isticmaalka sheegaysaa in qalab this waxaa laga heli karaa laba nooc oo kala duwan:

• The lyophilizate, loogu talagalay ee diyaarinta mudayo sinta ama xidid xal. Foomkan waa tiro lyophilized cad, oo aan lahayn inclusions shisheeye. Sidoo kale, waxay xidhmada kartoonada ka kooban dareeraha gaar ah taas oo uu leeyahay qaab dareere ah midab ah oo hufan.
• "Ademethionine" - kaniiniga in a baqshadda cad, biconvex iyo gadood. walax firfircoon Intaas waxaa sii dheer homonymous, taas macnaheedu waa ka kooban yahay iyo xubno ka kaabayaal sida MSC, ku Na-carboxymethyl silica iyo milmahayn mg.

sifooyinka pharmacodynamic

Waa maxay astaamaha ademetionine maalkii? tilmaamaha Codsiga bixisaa yidhi bandhigaa qayb choleretic, holekineticheskoe, detoxifying, cilmi nafsiga iyo hepatoprotective iyo anti-dejiyeyaasha iyo saamaynta antioxidant.

Sidaas darteed, waa ammaan ah in la ogaado in cunsurka loo arkaa daroogada awood u qaadidda dheecaan ah ee bile, iyo cadhaysiinina ay isa-soociddiisa ku jira xiidmaha.

Sidoo kale ogsoonow in daroogada analogs ah "Ademethionine" kuwaas oo hoos ku qoran, qabanaysa yaraanta SAM ah, laakiin waxa ay sidoo kale wuxuu kobciyaa formation ee beerka. Intaas waxaa sii dheer, waxan hab si fiican u kordhay ee plasma fiirsashada of cysteine, taurine, glutamine content ee beerka, sidaas caadi u dheefshiidka geedi socodka ee beerka iyo yaraynta heerka methionine ee serum.

Under xaaladaha waxa macnihiisu yahay "Ademethionine" ugu wax ku ool ah? Tilmaamaha loogu isticmaalo daroogada ayaa tilmaamaya in this si fiican u qabata la ductal iyo cholestasis cagaarshowga embriyaha. Waxaa qabata LCD conjugation iyo sulfation in unugyada beerka, ka dibna hoos ay sumoobo.

Sida ay sheegayaan warar ka mid ah khubarada, saamaynta choleretic iyo hepatoprotective ka dib markii joojiyo of therapy "Geptralom" keydiyo ilaa 3 bilood.

Marka uu u xilsaarayo lacagtan dadka qabatimay opioid'ka, raaceen by cudurka beerka, waxay hagaajinaysaa shaqo ee jidhka, qayilo geedi socodka monooxygenase, iyo sidoo kale gacan ka geysaneysaa dhaca calaamadaha caafimaad ee ka bixitaanka daroogada.

saamaynta lidka diiqadda ka dib markii codsiga ah ee daroogada this si tartiib tartiib ah uu yeesho. Si kastaba ha ahaatee, wuxuu xasilin doonaan in ka badan labadii toddobaad ee la soo dhaafay.

ka dhigan tahay awoodda ay ogeed ah

daawo "Ademethionine" nuugo? Tilmaamaha isticmaalka warar sheegaya in afka ay bioavailability waa 5%, iyo marka la isticmaalayo cirbad - 100%.

fiirsashada ugu sarreysa ee daroogada ee dhiigga inta lagu jiro dose hal ka mid ah hal kiniin lagu arkay for 2-6 saacadood.

The plasma protein-xidhxidhan state of this wakiilka yahay oo kaliya in yar oo tiro. Sidoo kale waa in la ogaadaa in daawadu ay si fiican u guskiisa galay BBB ah, iyo in ay isugu soo urureen sare si fudud loo ogaan karaa xitaa in dheecaanka lafdhabarka.

Biotransformation daroogada la kulmin beerka. Its reebay qeybtii labaad waa 1.5 saacadood. Dheefay daroogada ee kelyaha.

Tilmaamayaasha tilmaamahaasi of tahay

Maxaa loogu baahan yahay daawo "Ademethionine" (qiimaha daroogada ee hoos ku qeexan)? daawaynta Tan waxaa badanaa loogu:

• Calaamadaha murugada,
• cholestasis intrahepatic iyo dalalka pretsirroticheskih cirrhotic, oo ay ku jiraan dhowr tobnad cagaarshowga;
• cholecystitis chronic dibaddeeda ku dhagxiyaan,
• hepatitis chronic;
• cholangitis;
• sun cagaarshowga lesions of kala duwan asal, lugu daro viral, khamriga iyo daroogada (tricyclic murugada, antibiotics, antivirals, antitumor iyo anti-TB daroogada, afka uurka);
• cirrhosis,
• cholestasis intrahepatic in haweenka uurka leh,
• encephalopathy, oo ay ku jiraan ee la xidhiidha la'aan cagaarshowga (khamriga).

Oo mamnuucday isticmaalka

Under waxa xaaladaha waa in aan la qoro daawada "Ademethionine" ama "Geptral"? Tani macnaheedu waa in aan loo isticmaalin in hiddo ahaan saameeya wareegga methionine ah, iyo sidoo kale keenaya hyperhomocysteinemia ama homocystinuria. Sidoo kale waxaa waa u si aad u hesho in carruurnimada iyo qaangaarka iyo dareen sare si ay ademetionina.

Qadarka Qaadashada "Ademethionine" Kiniinka

khubaro Guest ayaa sheegaya in heshiis ay kula tahay in la qaado ee u dhaxaysa xiliyada cuntada aroortii, ma burburiyo ama cunidda. Xaaladdan oo kale, Oo looxa waa in laga saaraa baakada si toos ah ka hor inta isticmaalka.

qiyaasta maalin walba ah ee daawada tani waa 2-4 kiniin, iyo mudada therapy ku xiran tahay cadeymaha la heli karo.

Tilmaamaha isticmaalka xalka

Sidee baan u isticmaali xal isku duro "Ademethionine" analogues oo laga heli karaa farmashiye kasta? daroogada Tan waxaa suuq in kaabsoosha, maamula intramuscularly ama faleebo. Sayidka duridda xididdaha waa la fuliyay si tartiib ah.

xal daroogada waxaa loo diyaariyaa xaq hore ee duritaanka, iyadoo la isticmaalayo Barxo ah budada lyophilized, dareeraha ah, taas oo ah in sanduuqa kartoonka ah.

Ka dib markii la isku duro of daroogada ka hartay waa in la tuuraa.

Waa in la adkeeyay in foomka isku duro "ademetionina" leheyn xal xumadoodu iyo daawooyinka ay ku jirto a udhigo Ca.

qiyaasta maalin walba ah ee wakiilka for ampoules TOLC 1-2. Daaweynta daawo this socdaa muddo laba toddobaad ah.

Marka Dullaysanayay daroogada loo arkaa waxaa loo isticmaalaa in dose la mid ah. Marka la isku duro this waxaa lagu fuliyaa for 15-18 maalmood.

Haddii bukaanka u baahan yahay daawayn taageero, ka dibna waxaa loo wareejiyay qaab kiniin ah "Heptral".

waxyeellooyin

Maxay xun waxay keeni kartaa daawada "Ademethionine" (400 mg) More inta badan inta lagu jiro daaweynta daroogada this ee bukaanka isagoo shuban, calool xanuun iyo lalabo.

In dhif ah kiisaska isticmaalka "Geptral" xal, iyo sidoo kale ay kiniin foomka kartaa sababta horumarinta:

• IMP (i.e. kaadi mareenka cudurada);
• bararka doobta, dareen diidmo oo diidmo;
• paresthesia, walaaca, madax xanuun, hurdo la'aan, madax wareer, wareer,
• cuncun, daliilka maqaarka ee xasaasiyad, finan, anjioedema, dhidid,
• barar ah darbiyada xididdada maqaar saar, cudurada oo ka mid ah wadnaha iyo xididada dhiiga, dareenka gubashada ah;
• dibiro, afka oo qalala, matag, esophagitis, lalabo, calool xanuun, shuban, dyspepsia, cudurada functional of mareenka dheefshiidka, dibiro, calool biliary, beerka cirrhosis, dhiigbaxa qaybaha kala duwan ee mareenka caloosha iyo mindhicirka,
• xanuun, adkaashada murqaha;
• qidmeyntii, infalawansada-oo kale syndrome, qandho, qarqaryo, barar durugsan, asthenia.

qiimaha dawooyinka, analogs iyo dib u eegis

Waa imisa daawo sida "Ademethionine"? Qiimaha alaabta this ku saabsan yahay 1500 rubles kiniin per oo ku saabsan 1900 rubles halkii la muday.

medicament warbixinta waxaa lagu beddeli karaa haddii by yahay sida "acid Glutamic" "Karnith" "histidine" "carnitine", "Epilapton", "Elkar" doonay.

Maxaa qof ayaa ku yidhi ku saabsan dadka isticmaala daroogada? Sida ay sheegayaan wararka dadka bukaanka ah ee soo maray daroogada cudurka beerka "Ademethionine" waa gepatoprotektor shaqada dhabta ah oo kaliya. Bukaanka qaba cudurka ah "cirrhosis" doodaya in natiijada daaweynta ugu fiican ee lagu gaari karaa oo kaliya haddii daroogada la qaatay 2 jeer sannadkii koorso 3-bil.

Sida dhakhaatiirta, waxay sheegaan in daroogada "Ademethionine" ma siin saamayn fahmayaan oo degdeg ah cudurrada bararka beerka, raaceen by fadhiidka ah ee bile ee unugyada jidhka.