Unugyada antibodies TPO

Si aad u taariikhda, dhibaato dunida oo dhan qanjirka thyroid ma lumin ay ku tacaluqa. La'aanta iodine ee jirka lagu arkay 40% ka mid ah dadka waaweyn iyo 50% carruurta. Tan waxa u sabab ma ahan oo keliya in ay factor ee la iska dhaxlo, laakiin sidoo kale saamayn taban ee deegaanka. Xaaladdan oo kale, iodine ka imanba, waayo, ereygu wuxuu ahaa ee hormoonnada T3 iyo T4 sida, taas oo ku xidhan tahay tirada thyroid pituitary stimulating hormone (TSH), thyroid xakameeyo dhaqdhaqaaqa.

Waa in la sheegay in haddii qanjirka thyroid aan si ku filan ay gudanayaan xilkooda, cuduro gaar ah (shalalka) horumarinta ee jirka. Sayidka, waxbarasho la ogaado AT antibodies TPO ayaa tilmaamaya laga yaabaa in xaaladda gardaraale difaaca marka la eego jidhka. Taasi waa sababta noocyada kala duwan ee cudurrada thyroid waxaa loo xilsaaray in ay daraasadda of heer TSH dhiigga iyo jiritaanka unugyada AT TPO. Haddii dambe ayaa weli lagu arkay, ka dibna mid ka mid ah ku hadla ee cudur, shalalka.

AT TPO ka dhigan Insaymkaas ah oo ku lug leh ereygu wuxuu ahaa ee hormoonnada iyo SHCHZ inta lagu guda jiro hormoonnada iodization. Isagu waa antigen tireyodnogo xubin.

Sababta falanqaynta uma shaqayn karo sidii ogaanshaha cudurrada sida goiter, hypo- iyo tayroodh, cudurka Graves, diggaagga, tireoinid bararka. Sidoo kale, falanqaynta la qoray inta ay uurka leedahay si loo ogaado khatarta ah tireoinita dhalmada ka dib (10% haweenka ay leeyihiin cudurka this).

Waa in la ogaadaa in antibodies TPO, heerka ay qof weyn waa 5.6 U / ml, in jidhka bixisaa formation iodine firfircoon. Unugyada enzyme this ka hortagtaa ay hawl, sidaa darteed hoos u dheecaan ah ee hormoonnada T3 iyo T4. Laakiin ma aha in kiisaska oo dhan, perodoxida thyroid muujinaysaa joogitaanka geedi shalalka.

Daraasad Tani waa lagama maarmaan u ah ogaanshaha cudurrada thyroid. muuqaalka kore ee xadgudubyada ay shaqada waa calaamadaha ugu horreeya ee hypothyroidism. Marka la isticmaalayo habab aad xasaasi diagnostikiAT TPO, ka dibna cudurka waxaa laga helaa 94% bukaannada qaba cudurka Graves '- 84%, thyroid neautoimunnye cudurka - 15% dadka. Heerarka hoose ee Insaymkaas ah oo inta badan laga helo dad caafimaad qaba, si ay dhacdo in this su'aasha ah ee horumarinta cudurro kala duwan waxaa si liidata fahamsan yahay.

Waa in la ogaadaa in ay dhacdo in meesha TPO AT waa sii kordhay, tani waxay muujinaysaa habka a sida hypothyroidism sida. Noocan ah xadgudub u muuqda oo sabab u ah dhaqdhaqaaqa TPO antibody deceleration, heerka qayilo iodine, iyo, Sidaa darteed, korsasho ee ay foomka firfircoon. Xaaladdan oo kale, hormoonnada thyroid waxaa lagu ma ku dhexsameeysmo jirka.

Baadhitaanka ayaa maraa heerar kala duwan. In aadanaha, oo dhiiggiisa la soo qaaday, sida uu sheegay oo heer go'an ee TSH iyo T4. In the case of qaab T4 caadiga ah iyo TSH hooseeyo, ku sameeyey baaritaan daraasad ah T3. Xaalada danbe, waa inaad buuxisaa baadhitaan on antibodies AT TPO.

Sayidka, tilmaamo ee daraasadda uma shaqayn karo sidii looga shakisan yahay goiter, hypothyroidism iyo Graves Hashimoto ee. Laakiin waa in la xusuustaa in maqnaanshaha antibodies si perodoxida thyroid Ait uusan joogsanayn, joogitaanka ee jirka. helitaanka enzyme this in dhiig uusan siin kalsooni buuxda ku jiritaanka cudur ah, shalalka, tan iyo kiisaska intooda badan TPO AT waa la joogo in dadka kale u caafimaad qaba.

Laga soo bilaabo tan oo dhan waxaa soo socota in la ogaado ee enzyme tani waa lagama maarmaan si ay u fuliyaan sahan buuxa iyada oo ujeedadu tahay in la baabi'iyo khatarta ah Ait.

Sayidka, iyadoo aan loo eegin xaaladda, perodoxida thyroid waa caadi ahayn, shalalka imtixaanka ku filan xasaasi ah ee thyroid, si kastaba ha ahaatee, waxbarashada sida loo isticmaalo ku dhowaad hay'ad kasta oo caafimaad.