"Trimetazidine-Biocom MV": tilmaamaha loo isticmaalo, halabuurka, analogs iyo dib u eegis

medicament waxay leedahay saamayn taas oo teedu geeddi socodka dheefshiidka dedejiyey dhaca xubnaha neurosensory iyo myocardium ah. Inta aanad bilaabin daaweynta, aad leedahay si aad taqaanid waxa noqonaya daawo "Trimetazidine-Biocom MV". Tilmaamaha loogu isticmaalo, oo sideeda oo ka mid ah daroogada - macluumaad waxtar leh, kuwaas oo mudan tahay akhriska.

daroogada Form sii daayo, qaybaha

Daawada iska daayo a modified macnaheedu waa laga saaro qaab kiniin dahaarle, soo saaray iyadoo ay ku saleysan dihydrochloride trimetazidine. Nabarrada waxay ka kooban tahay 10 kiniin in pack wuxuu noqon karaa 1 ilaa 6. Mid ka mid ah kiniin ka kooban 35 mg ah qayb weyn ee. Qaab dhismeedka dhamaystirayaa milmahayn magnesium, povidone, aerosil, hypromellose iyo calcium hydrogen dihydrate phosphate.

Titanium dioxide, Macrogol waa kiniin qolof muhiim "Trimetazidine Biocom-CF". Tilmaamaha isticmaalka warar sheegaya in lagu daro walxaha kuwaas oo madaafiic ka kooban yahay hypromellose iyo xabagta cas bir ah.

saamaynta pharmacological

qalab Antihypoxanth kuu ogolaanayaa inaad si loo soo celiyo shiid caadiga ah ee unugyada, kaas oo ka dhacay sida ka dhalata isbeddellada loo kasin horumarinta xaalad bahal (ischemia, hypoxia). Kiniiniga joogsanayn yareeyo xaddiga ATP unugyada gacan ka horumar ah ee channels ra'iyi xuub, dhaqdhaqaaqa transmembrane ah sodium iyo potassium udhigo. Awoodaan si ay u ilaaliyaan homeostasis gacanta ee muddada daryeelka isticmaalaya medicament ah "Trimetazidine Biocom-CF". Tilmaamaha loogu isticmaalo sheegay in daawadu ay yaraynaysaa heerka ay geedi socodka lagu qayilo ee acids dufanka leh, oon ku qayilo a glucose weyn loo sameeyaa ilaalinta myocardial ka dhanka ah ischemia. tallaabo ee daroogada ku saleysan yahay badalista nidaamka lagu qayilo la acids dufan in glucose.

daroogada, dayactirka koorsada caadiga ah geeddi socodka dheefshiidka, si togan u saamaysaa xubnaha neurosensory iyo qalbigaba, yareysaa darnaanta xadgudubyada in socodka ra'iyi transmembrane horumarinta ischemia. Ku-simaha on nudaha wadnaha, daroogada yaraynaysaa tilmaamayaasha sida socdaalka, dhexgalka ee neutrophils polynuclear. Ku saabsan saamaynta daroogada "Trimetazidine-Biocom MV" diiwaanka ku jira xogta u taagan saamayn togan ku myocardium ayaa waxyeeleeyeen ischemia. daroogada Hemodynamic ayaa gabi ahaanba saameyn ku lahayn.

Pharmacokinetics

Nuugista qaadataa meel ku dhow gebi iyo si dhakhso ah. Isgaarsiinta la borotiinada plasma inconsequential (16%), heerka of bioavailability waa 90%. By la ansaxiyo Alwaaxdii waxaana ilaa iyo haatan marka heerka walaxda firfircoon ee jirka uu noqdo ugu badnaan, waxa ay gaareysaa ku dhawaad laba saacadood. Waxaa la og yahay in daroogada maraa dhaba iyada oo caqabadaha-unugyada dhiigga. Half-nolosha waa la fuliyay in shan saacadood. Daawada jidhka ka soo saaray by kelyaha, inta badan waxaa ka mid ah aysan waxba ka beddelin qaab.

maragga

"Trimetazidine Biocom-CF" (kiniin) edbinta waxaa loo isticmaali karaa si ay u hirgeliyaan daaweyn CHD dheer. Ujeeddada lagu muujiyay xaaladaha soo socda:

• baahida loo qabo in la hirgeliyo tallaabooyin ka hortag ah lacala dhacdo weeraro angina,
• wareer, joogitaanka kaas oo la xidhiidha lesions vascular,
• xanuunada cochle-vestibular isagoo nooca ischaemic (daraysa ee maqalka);
• cudurada vascular chorioretinal, Ulasocto ischemia.

prophylaxis angina waxa lagu samayn karaa iyadoo la isticmaalayo hal daroogada ama fulinta therapy adag.

sababo

Ku saabsan kiisaska daawo qaadashada aan loo baahnayn "Trimetazidine-Biocom MV" diiwaanka, dib u eegista waxaa ku jira xog muujinaysa adagtahay in daawada daawaynta ee gobolada kuwaas oo ah:

• dareen xad-dhaaf ah u dhigan isha ugu wayn qayb iyo waxyaabo kale;
• naas-nuujinta,
• inta lagu jiro dhalista.

Tan iyo ammaanka isticmaalka daroogada ee carruurta (ka yar 18 sano) iyo waxtarka daawaynta la isticmaalo aan la aasaasay, bukaanka sida taasi ka dhigan tahay lama magacaabay.

Daawada ahaan uu la muujiyay beerka aadanaha iyo kelyaha, taas oo tilmaamaysa sida ansixin kariyaatiniin waxaa si weyn hoos u dhacay (15 ml / min ama ka yar). Ma aha oo kaliya si ay u go'aansadaan tilmaamo iyo sababo daaweynta iyada oo suurtagal ah ee "Trimetazidine-Biocom MV". Qiimaha kale oo uu leeyahay qaar ka mid ah muhiimadda ay leedahay marka aad dooranayso medicament ah therapy. waxaa On ka dib waxaa ka wada xaajoon doonaa.

daaweynta daroogada

dose size hal waxaa lagu go'aamiyaa dhakhtarka (sida caadiga ah aan ka yarayn 40 mg laakiin aan ka badnayn 60). In 2-3 saacadood waxaa looga baahan yahay in uu fuliyo hab aqbaliddoodii. Duration ee therapy waxaa si gooni gooni ah adkeeyey jeer oo kala duwan.

waxyeellooyin

Ka hor inta therapy, waxaa lagama maarmaan ah in la ogyahay dhibaato suurto gal ah ka dib markii uu qofku cuno kiniinka ah u shaqeeyo "Trimetazidine Biocom-CF". Tilmaamaha loogu isticmaalo oo ka mid ah hab, oo ku salaysan, taas oo daaweynta oo waxyeelo badan waxaa ka mid ah xasaasiyad, ku muujiyey sida finan cuncun iyo maqaarka, dareen diidmo oo kale oo aan caadi jidhka. Inta lagu jiro daaweynta, mararka aad dhif u ah, bukaanada qaar ka mid ah waxay leeyihiin lallabo, matag gastralgia dhacdaa, waxaa la xusay.

Kiisaska ah qiyaasta xad dhaafka u daran oo aan ku soo go'an, iyo suuragalnimada in ay dhacdo uma badna. Sidaas darteed of aad iyo aad u dose lagu taliyay oo laga dheehan karo oo casaata wajiga, hypotension.

ganaaxyada

daaweynta ma hor joogsanayn, awood u leh inay la wado oo aan faragalin ku lug leh hawlaha ee waxqabadka taas oo u baahan falcelinta jireed iyo psychomotor deg deg ah.

Kiniiniga ma ku haboon yihiin in xididada loo weeraro angina iyo waxaa loo isticmaali karaa oo qura ujeeddooyin ka hortagga by bukaanka qaba weerarada sida.

daaweynta bukaannada qaba cudurka wadnaha waa hoos u dhac in looga baahan yahay maalin walba of Nitrate.

Qiimaha analogues daroogada, dib u eegista

Waa in la bartay ka hor inta daaweynta ka dhigan tahay "Trimetazidine" diiwaanka. Price sidoo kale waa macluumaad muhiim ah oo ay tixgeliyaan marka aad dooranayso daroogada lagu daaweyn jiray (prophylaxis), dhibaatooyinka wadnaha (cudurka halbowlaha wadnaha). Qiimaha saxda ah ee daroogada waa 100-165 rubles. 30 kiniin oo 189-208 rubles. 60 kiniin.

analoogga waxaa laga yaabaa in la dalbadaa "Preductal", "Antistius" ama "Trimethyl". daroogada daaweyn ay suurtagal tahay "Medarum", "Rimekor". Dhakhtarka ayaa laga yaabaa inuu bedelo daawada by magacaabista "Prekard", "Angiozyme", "Trimitard MV". Waxaa suurtagal ah in loola dhaqmo "Tridukardom", "Predizinom", "Trimektalom" ama "Metagardom". Siidi by dib u eegista ah, analoogga ugu caansan waa "Preductal" daroogada Tani waa wax ku ool ah, laakiin waa ka qaalisan yihiin "Trimetazidine". Tilmaamaha loogu isticmaalo, qiimaha muujinaysaa in daaweyn daroogada waa faa'iido, dib u eegista xaqiijin oggolyahay ee daaweynta this.

In dib u eegis ah medicament la sheegay in daawadu ay si fiican yahay meesha xanuunka ee wadnaha, waxaa fuliya ay hawsha si fiican. Maxaa yeelay qiyaasta sida bukaanka iyo dhakhaatiirta, calaamadeeyay isbedel wanaagsan, tus, jirka ka mid ah dadka qaata therapy, si fiican Arkaa jimicsi. Dad badan ayaa waxay sheegeen in ka dib markii dhowr maalmood oo daaweyn ay badiyay dyspnea, tachycardia qaadataa meel, cadaadis dhiig oo caadi ku soo noqonaya. Sida caadiga ah calaamadeeyay horumar maalintii afraad oo daaweyn ah, oo ku salaysan isticmaalka joogo lacagaha "Trimetazidine-Biocom MV". Tilmaamaha loogu isticmaalo, qiimaha muujinaysaa in daawada ma aha oo kaliya la heli karo laakiin sidoo kale wax ku ool ah, marka lagu daro, ayaa tirada ugu yar ee dhibaato suurto gal ah in inta badan ma yeeshaan. Xaaladan waxyeellooyinka arkay xaalado dhif ah.

Sidaas daraaddeed, waxaan siiyey warbixin faahfaahsan oo ku saabsan daroogada "Trimetazidine-Biocom MV". Analogues, qiimaha, hage, dib u ah oo ku saabsan daawada aad hadda loo yaqaan. Daawada waa in la magacaabay khabiir oo iyaga loo isticmaalaa in lagu dhigay qiyaas. Baahida loo qabo bedelka of medicament sida uu go'aamiyo dhakhtarka ku salaysan arrimo badan. tilmaamaha The kuu ogolaanayaa inaad si ay u sameeyaan daaweynta ugu fiican ee aan dhaawac.