Medicine 'methotrexate'. barashada

Medicine tilmaamaha "Daawada methotrexate" khuseeyaan category anti-metabolites ah, analogs pyrimidine. Micne ah: "Zeksat", "Treksan", "Triksilem" iyo kuwa kale.

Oo macnaheedu yahay "Daawada methotrexate" (kiniin) waxaa loo oggol yahay in ay operative sida wakiilka hal ama qayb ka mid ah chemotherapy adag.

By muujinaya waxaa ka mid ah myeloblastic leukemia iyo lymphoblastic, Blodcancerförbundet socodka marxaladda ka dib, lymphosarcoma. Iyadoo qayb ka ah dawada ah himiolecheniya dhafan guide "Daawada methotrexate" talinaysaa kansarka ugxansiduhu, sambabka, naasaha.

At qaadasho sare (inta aad qaadaneyso filinata calcium) daroogada loogu osteogenic sarcoma, buro Ewing ee, choriocarcinoma sarcoma makaanka oo unug jilicsan.

Dejinta (duray) waxaa loo isticmaalaa in laga nafiso calaamadaha oo ka mid ah nabarada maqaarka psoriatic.

Oo macnaheedu yahay "MTX" in qaab-dhismeedka kiimikada (user ku jira macluumaad sida) u dhow folic acid at this leedahay saamayn ka soo horjeeda. Sida antagonist ah antimetabolite iyo bixinta saamayn antifolievym, daroogada caanuhu qeybinta unug, horumarinta unugyada si firfircoon ku faafeen, dhuuxa lafaha iyo sidoo. medicament The "MTX" kordhinayaan in hoos u koritaanka neoplasms malignant.

Dawada waxa qoray gudaha.

In daaweynta isku dhafan ee buuga daroogada "Daawada methotrexate" talinaysaa dadka waaweyn ay ku 0,03 garaam oo laba jeer toddobaadkii. Waayo, carruurta qiyaasta maalin kasta - 0.02 grams halkii centimitir square ee bedka jirka.

Duration daaweynta - ilaa laba toddobaad.

Dabcan Intensive ku lug leedahay magacaabista qiyaasta dadka waaweyn loogu 0,02-0,025 garaam maalin kasta. Duration daaweynta - ilaa shan maalmood.

In koorsada qaadashada daawada "Daawada methotrexate" Buuggan ku talinaysaa in la qaato nasasho in hal ama laba toddobaad ah.

Daawada ahaan uu gobolada immunodeficient, cudurka beerka, Torombositobiiniya, leukopenia, dhiig yari (oo ay ku jiraan aplastic iyo apoplastic) diidmo.

Ma aha xog ku filan si ay u qabtaan koorsooyin ku daweyn of daawo "Daawada methotrexate" uurka leh iyo kuwa nuujinaya. In xidhiidh la leh daawo this ee muddada dhalmada ka hor iyo inta lagu jiro nuujinta lagu qorin.

Waxaa ay leeyihiin daawooyinka "Daawada methotrexate" waxyeelo. daroogada waxay keeni kartaa hadlidda, lalabo, shuban, bukashada xuubka afka (stomatitis). isticmaalka muddo dheer ee daawooyinka "MTX" calaamadeeyay nabar leh dhiig xuubka afka ah qof kolit, hoos dacwadood dhiig xinjirowga, timaha, hoos content ee unugga dhiigga ku. Xaaladaha qaarkood, caabuq laga dheehan karo, u badan tahay inay keeni hepatitis sun ah (caadi ahaan marka la dalbanayo qaadasho sare), lesions kelyaha.

Si looga fogaado horumarinta cawaaqib aan loo baahnayn ee koorsada-daweynta waxaa la fuliyay iyada oo ay kormeerayaan adag ee dhakhtar.

Xaaladdan oo ah qiyaasta xad dhaafka aan go'an daliilka gaar ah. Soo ogaanshaha xaaladda waa la fuliyay by waxyaabaha daroogada "Daawada methotrexate" plasma ah.

ganaaxyada

Agabka in aan loo isticmaalin effusion, ascites, boogaha, ulcerös kolit, cudurka kelyaha pleural ama turqo.

Ha qaadan varicella daawada (oo ay ku jiraan dhawaan wareejiyo ama ka dib markii xiriir la cudurka ah ee), Zoster herpes iyo cudurrada kale ee ba'an ee asal ahaan faafa.

Bilowga iyo in koorsada daawada loo baahan yahay in la xakameeyo sawirka dhiiga durugsan, beerka iyo kelyaha waxqabad.

In codsanaya daroogada ee psoriasis ama rheumatoid arthritis, Xisaabta buuxa ee dhiigga ka dhigay bil ah ugu yaraan hal mar.

Intii lagu guda jiray cilmi waxaa laga dhex helay saamaynta mutagenic iyo kansar daawada "Daawada methotrexate".