Guide amlodipine

Daawo "Amlodipine" malaha yaqaan in ay dad badan oo gacan koowaad. Asal ahaan, daroogada taas waxaa loo qoray in bukaanka angina. Ha ka fikiro si aynu "Amlodipine" daroogada, kuwaas oo tilmaamaha ku qoran warar soo socda.

Curiska. Mid ka mid ah kiniin (5 mg) ku jira besylate ku amlodipine walax firfircoon. Sida excipients isticmaalo lactose, istaarijka baradho, collidone, cellulose mikrokristallin, milmahayn magnesium.

description Guud. Kiniiniga "Amlodipine" caddaan ama ku dhawaad la caddaan doonaan si wadajir ah labada dhinac. Mararka qaarkood waxaa laga yaabaa in iftiinka marbling joogo.

Pharmacodynamics. Dihydropyridine derivative - blocks calcium channels "gaabis ah" jiilka labaad ee uu leeyahay gipotezivnoe iyo saamaynta antianginal. La xiriira receptor dihydropyridine iyo xanbaarsan xanibaadda ee channels calcium, taasoo marinka transmembrane ah ee atammada kalsiyamku galay gacanta (ilaa xad ka weyn in muruqa siman derbiyada weel badan ee myocytes wadnaha). saamayn Antianginal waxaa keena ballaarinta halbowleyaasha iyo arterioles ku yaala ubucda: darnaanta umenshaetsnizhaet angina ah ischemia myocardial, halbowlaha durugsan u fidiya, taasoo tirada guud ee iska caabin ah dhuumaha ugu sarreeya, marka lagu daro waxay ka caawisaa si loo yareeyo loader ku saabsan waxyaalaha qalbiga ku jira, yaraynaysaa qalbigiisa u baahan oxygen ah. In bukaanka qaba angina, qiyaasta maalin kasta hal kordhiyaa waqtiga baxsad fiznagruzki ah, gaabisaa horumarinta ischemia iyo angina, oo lagu daray wax walba yaraynaysaa badnaanta isku weeraro angina iyo baahida nitroglycerin. Sayidka, bukaanka qaba angina u baahan yahay hagaha "Amlodipine" caddaynta this.

Pharmacokinetics. Ka dib markii maamulka afka ee daroogada si tartiib ah nuugo ka soo mareenka caloosha iyo mindhicirka. bioavailability celcelis Absolute waa 64%, ugu xoog ku serum dhiigga 6-9 saacadood ka dib. dheelitirka deggan dhiiggiisa la arkay maalintii 7-dii. Cuntada wax saameyn ah kuma nuugista ee amlodipine. In bukaanka dadka waayeelka ah (ka weyn 65 sano) Digo ee daroogada waa mid gaabis ah marka loo eego dhalinyarada, laakiin farqiga tani ma aha caafimaad oo muhiim ah.

"Amlodipine" barashada taas oo ka kooban dhammaan xogta muhiimka ah ayaa muujinaya soo socda si aad codsiga: hypertension halbowlaha ah (isku dhafan oo kale ama la mid ah hab monotherapy), angina exertional, angina vasospastic (angina Prinzmetal ee).

Sababo.

- dareen sare si ay qayb firfircoon iyo taagayo kale dihydropyridine;

- hypotension qaab daran;

- lama filaan ah cardiogenic, burburkii;

- angina deganayn (marka laga reebo - angina Prinzmetal);

- nuujinta iyo uurka;

- loogu talagalay dadka ka yar 18 sano ee ammaanka iyo saamaynta aan la aasaasay.

The qiyaasta iyo habka codsiga. Qaado "Amlodipine" edbinta bixisaa sida soo socota: gudihiisa, qiyaasta ugu yar ee 5 mg, ugu badnaan - 10 mg 1 mar maalintii. Marka qiyaasta hypertension dayactirka noqon kartaa 5 mg maalintii. Marka stroke qaataa hal mar 5-10 mg maalintii. bukaan oo khafiif ah, iyo sidoo kale bukaanka hoose iyo bukaanka qaba beerka oo yaraada shaqeeya maamulo 2.5 mg.

tilmaamaha gaarka ah. Inta lagu guda jiray daawaynta "Amlodipine" Waa in la raaco miisaanka iyo isticmaalka walxaha sida sodium, mararka qaar u baahan cunto gaar ah. Waxaa muhiim ah in la raaco nadaafadda afka iyo ilkaha, booqo dhakhtarka ilkaha si joogto ah (si looga fogaado in xanuun iyo dhiig ciridka). By kordhaya qiyaasta ee dadka waayeelka ah waxay u baahan tahay la socodka taxaddar. Saamaynta daroogada on awood u leh inay baabuur ay jirto xog lahayn. Si kastaba ha ahaatee, waa in la dhasha maskaxda ku haysaa in dadka qaar ka mid ah waxay keeni kartaa wareer yar iyo hurdo.