Drug "allopurinol": dib u eegista dhakhaatiir, tilmaamo, waxyeellooyin

Si aad u taariikhda, daroogada "allopurinol" waa aasaasi ah (hoose, dhexe iyo pathogenetically ku xeeldheer) daroogada ah oo loo isticmaalo in lagu daaweeyo cudurrada sida turqo. Qof kasta oo ka hor inta aadan isku daydid wax cusub, isku dayaya in ay ka heli macluumaad ugu faa'iido leh oo ku saabsan. Sidaas daraaddeed waxaannu ku bixiyaan in ay faahfaahin dheeraad ah ka qaban marka la mid ah waa in lagu dabaqaa "Allopurinol". Reviews bukaanka iyo dhakhtarrada lagu soo bandhigi doonaa in our article oo waad garan doontaa waxa ay ka cabsada inta aad qaadanaysid daawada this.

sifooyinka pharmacological daroogada

"Allopurinol" waxa loola jeedaa diyaarinta kooxda protivopodagricakih. The walax ugu weyn ee firfircoon - allopurinol iyo oksipurinola metabolite firfircoon. Kuwani saamaynta pharmacodynamic ay sabab u tahay xadgudub ereygu wuxuu ahaa ee acid uric leh saamayn urostaticheskogo horumarinta. Tani waxay ugu dambayntii waxay keenaysaa in hoos u dhac ay fiirsashada, raaceen by kala diridda urate.

Sababo la milmi "allopurinol" wanaagsan ayaa bioavailability sare. Daawada waxaa si fiican u nuugo ka Lumen ee xiidmaha yar. In caloosha galay wareegga systemic ma dhici. iyadoo ay wada joogaan ee plasma dhiig ayaa la arkay ilaa nus saac ka dib markii maamulka, iyo ka-fiirsashada ugu arkay saacadood 1.5 ka dib. Iyadoo la raacayo, midda ugu badan ee metabolite ah allopurinol - oksipurinola arkay saddex saacadood ka dib markii maamulka afka.

daroogada waxay leedahay nus-cimri dheer iyo tan iyo markii ay awood u cumulation. Bukaan-bilowga ah ee daaweynta, waxaa jira fiirsashada kordhaysa oo ah daroogada in degto hal ilaa laba todobaad ee therapy ka dib. Sababo la tirtiridda "Allopurinol" dheer (dib u eegista ah ee dhakhaatiirta waxa ay xaqiijin) laguma talinayo in la isticmaalo dadka qaba kelyaha. In bukaanka qaba raagayaan cumulation function excretory kelyaha aan arkay.

"Allopurinol": muujinaya in loo isticmaalo

Rogaal dhakhtarro ku dejinaya sheegashada daroogada this in kaasu waa kan ugu wax ku ool ah iyo waa laga caddeeyey in xaaladood oo hyperuricemia (heerarka sare ee uric acid halkii mugga unit oo dhiigga ah) at:

• arthritis gouty (turqo);
• cudurada Fistula urate (nephropathy, urolithiasis);
• cudurada oncological dhiigga;
• cillado lagu dhasho nidaamka eulayska.

Xaaladaha qaarkood, isticmaalka suurto galka ah ee daroogada lagu daaweyn jiray nephropathy carruurta urate, kaas oo u muuqday on asalka ah ee daaweynta leukaemia in cudurada lagu dhasho ee la xidhiidha-shiid oo yaraada of acid uric, hyperuricemia sare asal ahaan kala duwan.

Features of daroogada

kiniiniyada "Allopurinol" (dib u eegista digay waafaqsan adag la talooyinka daawo) waxaa laga qaadaa cuntada ka dib, iyagu waa wax la dhigan tahay wax aan macquul aheyn in la calaliyo, laakiin halkii ay cabniinka oo dhan oo cab ugu yaraan hal galaas oo biyo diiran.

Dadka qaadanaysid dawadan, waa in aad had iyo jeer la socon cuntada, iyo in ay dhacdo baadi cuntada lagama maarmaanka ah si ay ula qabsadaan oo ay qiyaasta, laakiin kaliya iyada oo ay kormeerayaan of takhasuska dhigata.

Qiyaasta loo baahan yahay in lagu daweeyo "allopurinol" daroogada waxaa ka go'an ku xiran tahay content ee uric acid ee dhiigga. Sida caadiga ah, waxa ay u dhaxeysa 100 ilaa 300 mg halkii hal mar "allopurinol" diyaarinta. Reviews bukaanka iyo dhakhtarro ku saabsan kacmaha this wanaagsan, sida daroogada waxaa la qaataa hal mar kaliya maalintii.

therapy turqo bilowdo magacaabidda 100 mg oo daroogada ah hal mar maalintii. In case of la'aanta oggolyahay iyo masaakiinta hoos qiyaasta acid uric waxaa si tartiib ah kor u kacay (100 mg laba ama saddex toddobaad kasta), taasoo keentay in shaybaar-daweynta wax ku ool ah ay ka taliyaan ee heerarka acid uric. Xaaladaha noocaas ah, qiyaasta celceliska iyo dose dayactirka ku xiga u dhaxeysa 200 ilaa 400 mg, laakiin xaaladaha qaar ka mid ah, qiyaasta noqon kartaa ilaa 800 mg. Xaaladdan oo kale, waxay u qaybsan yahay dhawr jeer maalintii.

In magacaabista daroogada si uu bukaanka qaba la'aan kelyaha waa in ay diiradda saaraan ku ansixin kariyaatiniin.

Sababo for "Allopurinol" naqshada

Daawada waa u bukaanka qaba xumaanshaha kelyaha ee daran, iyo sidoo kale uurka leh iyo kuwa nuujinaya. Waxaa sidoo kale aan lagu talinayaa in daroogada si uu bukaan isagoo dareen xaasaasi ah ama diidmo in mid ama ka badan qaybaha of diyaarinta. Waa mamnuuc in la isticmaalo daroogada ee bukaanka qaba heerarka Xadka of uric acid ee plasma dhiig, sababta oo ah hoos u guul lagu gaadhi karaa in la hagaajiyo cunto.

"Allopurinol": waxyeellooyin

Reviews of bukaanka loo isticmaalo daroogada markii ugu horeysay, ayaa muujinaya in inta badan waa sii daridda suurto gal oo kordhay calaamadaha turqo la ah ee weerarada waxa loogu yeero. Laakiin tani ifafaale muddo gaaban, oo muhiim ma ahan in ay ka baqin ku filan si ay u joojiso therapy. Laakiin in ay dhacdo wax kasta oo finan, raaxo la'aan ama maqan calaamadaha hore waa inaad isla markiiba u sheegtaa dhakhtarkaaga. In habkan of "Allopurinol" waa in la isla markiiba la joojin, iyo sida waayitaanka calaamadaha farsamo karaan dib-u-u yeelaan daroogada, laakiin qiyaas ka yar (50 mg). Admission waa in la qabtaa iyada oo ay kormeerayaan dhow dhakhtarka xaadirka ah iyo in qol ah.

Waxaa ka mid ah dhibaato ka mid ah habka dareemayaasha jirka iyo hawlaha maskaxda sare waxay keeni kartaa niyad-jab. On qayb ka mid ah horumarka Dulmiga nidaamka hematopoietic dhuuxa lafta waxaa dhif arkay iyadoo dhacdo ee Torombositobiiniya, anemia aplastic.

Marka la helo daawada laga yaabaa in cudurada dheefshiidka, sida sonkorowga, heerarka sare ee acids dufanka leh ee plasma dhiigga.

nidaamka wadnaha-vascular laga yaabaa in hypertension, bradycardia.

Inta jeer ee dhibaato in ay daroogada waxaa kordhay joogitaanka renal failure in bukaan.

foomka Release iyo qiyaasta

"Allopurinol" heli karaa qaab kiniin ah (30 ama 50 kumbiyuutarada. On baakadka) ee qiyaasta ah 100 ama 300 mg oo firfircoon, halkii kaniini. In suuqa gudaha jirto "Allopurinol Sandoz 300". Reviews waxaa ka mid ah positive, sida daroogada ee qiyaasta lagu qoro hal mar oo keliya maalin kasta, shiidaa masaxdaa waxaa macquul ah inuu seegi doono xerada qaxootiga ee daroogada.

Sunta iyo badinta daroogada

Sunta dhif arkay, laakiin waxaa jira kiisas dhoos keli ah 20 garaam oo daroogada ah. Xaaladdan oo kale, waxaad la kulmi calaamadaha soo socda: wareer, matag, yalaalugo, shuban. In la'aan kelyaha, iyo maamulka joogto ah qaadasho sare ee daroogada ayaa lagu arkay calaamadaha daran sarkhaan ee foomka of qandho, hepatitis, kelyaha ba'an.

Daaweynta sumoobidda degdegga ah iyo badinta, astaamaha, loogu talagalay hi tirtiridda daroogada jidhka ka. No daawo gaar ah. Waayo, Digo dhakhso ah daroogada jidhka ka hababka dialysis waa naanin wax ku ool ah.

Reviews

Marka la eego xaqiiqada ah in muddada raasamaal ee daroogada ee dhiigga (at-fiirsashada ku filan si ay u bixiyaan tallaabo-daweynta) waa celcelis ahaan hal toddobaad, bukaanka ka cabanaya turqo, waa in la dalbadaa ficil ahaan nolosha "allopurinol". Reviews dhakhtarro waa dirayaan: daroogada si fiican ayaa laftiisa xaqiijiyay. Laakiin tani ma aha a "pill mucjiso" in ku yeelan kartaa cabitaan iyo illoobin ku saabsan cudurka. Turqo - waa halkii waa hab nololeed halkii cudur joogto ah. Laakiin waa "Allopurinol" waxay ka caawisaa in la xaddido heerka of jėrto iyo looga hortago xaalad xumeyd ee cudurka iyo horumarka dheeraad ah.

In la eego sahlo, "Allopurinol" jawaabta daroogada iyadaa ka dhakhtarro sidoo kale waa wanaagsan, sababtoo ah kiisaska intooda badan bukaanka waa in la qaataa daawada maalin kasta hal mar. Tani waxay yaraynaysaa in jaaniska ah ku seegay soo dhaweynta ee medicament iyo, sidaa darteed, waxay kordhisaa tayada dawaynta ka.

gunaanad

Sayidka, daawaynta ugu weyn ee turqo - "Allopurinol". xirfadlayaasha Reviews iyo bukaanka, taas macnaheedu waa qaadashada, wanaagsan, iyo this Xaqiijiyay oolnimada of medicament la daaweynta turqo iyo xanuunada-shiid acid uric. Thanks to isticmaalka daroogada, tiro badan oo bukaan helaan rajo si loo yareeyo dhibaatooyinka sonkorowga.