"Domidon": tilmaamaha loo isticmaalo, iyo waxa uu yahay, waayo,

Iyadoo cudurada functional of mareenka dheefshiidka wajahay qof kasta. Inta badan, raaxo ee gobolka gaastari kici sababta oo ah nafaqo xumo iyo aan habboonayn. Si loo hagaajiyo dheefshiidka iyo dardar udhigto, gastroenterologists talineynaa qaadashada hab gaar ah. Mid ka mid ah iyaga ka mid ah soo gudbiyey daawada "Domidon". Tilmaamaha loogu isticmaalo, warcelin iyo tilmaamo ah daroogada this hoos lagu soo bandhigay.

Form, halabuurka, baakooyinka daroogada

Medicament "Domidon" barashada waxa lagu kaydiyaa baakadaha laga sameeyay baakado, soo saaray qaab kiniin ah. Waxay ka kooban yihiin domperidone ah, iyo maaddooyinka kale sida laktosmonohydrat lactose, povidone, galleyda, cellulose mikrokristallin, titanium dioxide, istaarijka pregelatinized, milmahayn magnesium, sodium lauryl sulfate, tones polyetylen 4000, methylcellulose hydroxypropyl ama sepifilm 752 Blanc.

In iibinta xarunta this aado unugyada dusha ka.

Farmashiiste

Waa maxay daawada sida "Domidon" (kiniin)? Tilmaamaha Isticmaalka sheegayaa in ay tahay motility GI qaadka ah. Its mabda 'hawlgalka lagu sharaxay by awood u leh inay xannibi ee receptors D2-dopamine. Sidaas darteed of saamaynta this kordhiyaa mudada dhaqdhaqaaqa peristaltic 12 xiidmaha tiperstnoj iyo meesha antral gastric. Sidoo kale dedejisaa soo saaris ah xubnaha sheegay oo waxay kordhisaa waa ohyahay ee hunguriga (endetarms- hoose).

daawo waxa uu leeyahay saameyn ah kuma laha dheecaan gastric. Its saamayn anti-emetic ay sabab u saamayn gastrokinetic isku dhafan, oo iska soo horjeeda ee receptors dopamine degaanka keebka chemoreceptor ah, kuwaas oo ku taalla meel ka baxsan caqabad dhiig-maskaxda. Intaa waxaa dheer, daroogada this meesha dhibaatooyin iyo lallabo.

sifooyinka ogeed

Waa maxay dabeecad u ah kinetics daroogada "Domidon"? Tilmaamaha loogu isticmaalo ayaa sheegay in qalab this si dhakhso ah oo si buuxda u nuugo ka soo xiidmaha. Waxaa la metabolized ee beerka iyo caloosha iyo mindhicirka derbiyada mareenka, ku dheehan ayaa bioavailability hooseeyo (15%).

Hoos u juice aysidhka gastric iyo cunista si weyn hoos u dhigi iyo yareeyaan ka nuugista ee domperidone. Its fiirsashada plasma peak gaaray hal saac ka dib markii uu qofku cuno.

Isgaarsiinta ee daroogada si uu borotiinada plasma waa qiyaastii 91-94%. Waxaa liidata waa guskiisa dhex BBB ah, laakiin ma sidoo kale caanaha hooyada (heerka ku saabsan 1/4 fiirsashada guud waa in dhiigga).

Isbadal noolaha ee diyaarinta waxaa lagu fuliyaa by N-dealkylation iyo hydroxylation.

Markii ugu bar-nolosha ee daroogada waa 7-10 saacadood. In kelyaha (daran), tiradaasi sii kordhaya.

daroogada dheefay jidhka ka la socdaan saxarada iyo kaadida.

Tilmaamayaasha gelitaanka

Xaaladaha qaarkood, dadka waaweyn ee u xil "Domidon" kiniin? Isticmaalka daroogada this muujiyey matag iyo lallabo iyo sidoo kale xanuun caloosha sare, dareen ee buuxnaanta iyo laab.

Sida loogu talagalay carruurta, waxay ku talinaynaa in xarunta oo keliya, waayo, lalabo iyo matag.

sababo

Marka aan si ay u isticmaalaan daroogada "Domidon" (tilmaamaha loo isticmaalo iyo waxa ay tahay - oo dhan ayaa loo sheegi doonaa in this article)? Sababo qalab this yihiin:

• dhiigbaxa caloosha iyo mindhicirka,
• diidmo,
• daloolin xiidmaha / caloosha ;
• xirma xiidmaha farsamo;
• hypophysis buro (prolactin-secreting);
• isku dhafan oo foomamka afka "erythromycin", "ketokonazol" ama inhibitors kale ee CYP 3A4, iyo sidoo kale wakiilada oo dheerayn ku bareeg Q-T.

Drug "Domidon": tilmaamaha loo isticmaalo

kiniinka loo tixgeliyaa waa in la qaato kaliya gudaha cuntada ka hor. Marka aad hesho daawo hadhuudh ah oo ay nuugista ka dib waa xoogaa gaabis ah.

Carruurta ka 12 sano iyo dadka waaweyn, daawada waxaa loo qoray 10-20 mg saddex jeer maalintii. Qiyaasta ugu badan ee maalin walba ah ee daroogada ahaa 80 mg.

Muddada daaweynta aasaasiga ah - 4 toddobaad. Haddii loo baahdo, isticmaal dheeraad ah ee daroogada ayaa loo baahan yahay in la tasho dhakhtarkaaga.

Iyadoo horumarinta kelyaha waa in la yareeyo badnaanta ee daroogada. Iyadoo la tixgelinayo beerka, haddii ay taasi ku, waxa aan la qoray.

waxyeellooyin

Ma muuqaalka kore ee reactions daawo loo kasin "Domidon"? Tilmaamaha loogu isticmaalo sheegay in waxyeello ka soo gaartey sida dhacdo:

• in la kordhiyo heerarka prolactin;
• anaphylaxis ;
• yaacsanaan, kacsanaan,
• bararka, hagaagay heerka Q-T, uurkuna waa, dysrhythmia iyo wadnaha bareeg;
• afka oo qalala, disorder extrapyramidal, madax-xanuun, harraad, hurdo la'aan, caro, wareer, la qabsi, feejignaan xumo, gariir,
• xanuunada caloosha,
• gynecomastia, galactorrhea, amenorrhea;
• cuncun, gubta,
• kaadida oo soo noqnoqda, finan maqaarka ah,
• stomatitis, conjunctivitis,
• asthenia, xanuun lugaha,
• kordhiyo AST, ALT iyo kolestaroolka.

talooyin gaar ah

Maxaan ku wargalisaa bukaanka, ka hor inta aadan ku meelayn daroogada ah "Domidon"? Tilmaamaha Isticmaalka sheegayaa in qalab this ma lagu dari karaa antisecretory iyo daawooyinka ashitada.

Waayo, daaweynta carruurta ka yar 12 sano jirka ah oo leh miisaan jirka ka yar 35 kg isticmaalo daawada waa in aanay noqon.

Inta lagu guda jiro daawaynta la daroogada this waa in ay iska ilaaliyaan maamulka wadada iyo mashiinada khatar shaqeeya.

dib u eegista macaamiisha

Hadda oo aad ogtahay waxa muuqaalada mid caan ku ah daroogada "Domidon". Tilmaamaha loogu isticmaalo iyo waxa uu yahay, waxaan ku kor sheegay.

macaamiisha intooda badan la isticmaalayo xarunta this sheegay in ay si waxtar leh ay meesha ka laab, dhibaatooyin iyo lallabo. Sidoo kale, daroogada kordhinaya udhigto degdeg ah caloosha, yaraynta dareenka of baroor iyo raaxo in ugu yaraan.

Faa'iida keliya ee daroogada tani waa tiro badan oo ah waxyeelo.