Daawada "Concor Korintos": muujinaya in loo isticmaalo, dhigooda dhabta ah

cudurrada wadnaha iyo haatan ku dhow yihiin in meesha ugu horeysa ee heerka dhimashada ee dunida. Iyo dhibaatooyinka ka helay ka yar sannad kasta. Haddii aad hore oo ku saabsan Wadnaxanuun myocardial infarction sheegay, waxay ahayd su'aal ku saabsan da'da ugu yaraan 45-50 sano, maanta cudurkan dhufan karo, iyo 30-sano jir ah.

Modern Farmashiyaha ayaa mass ah medicaments waayo, la dagaalanka dhibaatooyinka "wadnaha" ee heerarka kala duwan ee horumarka cuduradan. Mid ka mid ah group of daroogada kuwanu waa blockers beta. Mabda'a hawlgalka lacagta waa in la xiri receptors beta-adrenergic ee wadnaha ah. natiijo waa hoos u dhac in garaaca wadnaha, taas oo horseedaysa hoos u cadaadiska dhiigga iyo in la wanaajiyo xaaladda guud ee qofka.

Beta-blockers hadda horumariyo noocyo kala duwan oo weyn. Mid ka mid ah si weyn loo isticmaalaa in horumarka dhanka wadnaha waa "Concor Korintos." Tilmaamayaasha, dib u eegista ee medicament sifaha daroogada in ay ku filan wax ku ool ah oo ka mid ah bukaanka qaba cudurka wadnaha ee dalbadaan.

Tiirarka ugu muhiimsan iyo qaab daayo daroogada

qaybaha ugu muhiimsan ee diyaarinta "Concor Korintos" - hemifumarate bisoprolol. Sida ay laftu kaabayaal liiska ku filan badan oo walxaha: galleyda, cellulose mikrokristallin, crospovidone, milmahayn magnesium, Kolloidol Silicon dioxide, ammooniya phosphate calcium hydrogen.

Daawada waxaa la siiyaa macaamiisha qaab kiniin wadnaha-dahaarka cad-dahaarle (ee ay ka kooban - macrogol 400, dimethicone 100, gipromelaza, titanium dioxide). Khatarta ah ee labada dhinac kala qaybinaya galay labadii loox "Concor Korintos." medicament Baako oo la soo saaray ee finan-bireed, kuwaasoo mid walba uu la soldered laga yaabaa in 10, 14, 25 ama 30 gogo '.

Bukaan-socodka waxaa si joogta ah u arag in farmasiyada iyo daawada "Concor". Tan iyo magacyada labadan daawooyinka aad ula mid yihiin, farmashiistayaasha inta badan u leeyihiin in ay ka jawaabaan su'aalaha ku saabsan farqiga u dhexeeya "Concor" ka "Concor Korintos." Sidaas daraaddeed, farqiga kaliya ee waa in xaddiga content ee qayb weyn ee firfircoon - bisoprolol. macaamiisha "Konkor" iibsan kartaa kiniin isagoo in ay ka kooban waa 5 ama 10 mg ah ee firfircoon, halka "Konkor Korintos" - 2.5 mg.

Macaamiisha u baahan yihiin in ay ogaadaan in iibka daawooyinka-blockers ee farmashiyaha farmashiistaha baahan doontaa inaad keento warqad dhakhtar.

pharmacodynamics

"Concor Korintos" ayaa beta ee doorashada 1-adrenoceptor saamayn ku furid a. Nuxurka of saamaynta ay - kartida si loo xakameeyo gudbinta falalkooda dareemayaasha ee receptors adrenergic. Sababtan awgeed daroogada waa ay awoodaan in ay ku isticmaali antihypertensive, antiarrhythmic, saamaynta antianginal.

saamayn Hypertensive "Concor Korintos 'dib u eegista ah dhakhaatiirta la xiriira xaqiiqda ah in bisoprolol yaraynaysaa mugga daqiiqadii dhiigga. Intaa waxaa dheer, Iscelin barbar dhigay nidaamka renin-angiotensin. Saamaynta ugu weyn caafimaad oo waxaa lagu gaarayaa 5 maalmood helo daroogada ka dib. BP la dejiyo by dhamaadka bisha labaad ee daawooyinka lagu daweeyo "Concor Korintos."

Ppokazaniya medicament loo isticmaalo sida damaanad deggan saamaynta antianginal by yaraynta baahida oxygen myocardial ay sabab u tahay hoos u dhac ah ku garaaca wadnaha. Sidoo kale, waa inaan sheegaa in isticmaalka daawada this kor u dheereyn diastole.

saamayn Antiarrhythmic macnaheedu yahay "Konkor Korintos" sabab u qaxo si xun u saameyn arrimood oo ay ka mid saamaynta qayb ka mid ah xakamaynta dabacsanaadaan of Department habdhiska, geedi socodka xakamaynta abuuro karsado korontada ee Guntin Dalqada wadnaha ku, Iscelin of dhaqdhaqaaq korontada ee myocardium ah.

Si ay u muujiyaan daroogada, iyo kan - lahayn?

Maxay yihiin hab ee muujinaya "Concor Korintos" loo isticmaalo? dib u eegista Consumer xaqiijiyo tayada sare ee daroogada. Waxaa lagu talinayaa in ay qaataan si loo daaweeyo wadnaha iyo ka hortagga horumarinta xaaladaha sida in marxaladaha hore. Si aad u noqoto dhabta ah, shaqaalaha caafimaadka ayaa kuu qori beta-xanibaha in ay aqbasho si loogu daweeyo adkaysta wadnaha chronic la dhimay shaqada systolic ventricular bidix. Sida caadiga ah "Konkor Korintos" qoray in barbar celiyeyaasha ACE , wakiilada durayo, glycosides wadnaha.

In mid ka mid lahayn rabitaan ah inuu ku meeleeyo daroogada laftiisa on iyaga u gaar ah, oo aan tilmaamaha dhakhtarkaaga, waxaa lagama maarmaan ah si aad u hesho qof aqoon u leh liiska cajiib ah sababo la siiyo wakiilada ee "Concor Korintos."

Marka laga reebo khasab dhammaan tilmaamaha daawo in la mamnuuco joogitaanka dulqaad in qaybaha ay uu ka samaysan yahay daroogada iyo da'da bukaanka (illaa 18 sano loo dhan yahay - war ah kama on waxtarka iyo ammaanka), waxaa weli jira badan oo ka mid ah sababaha iyo xaaladaha ka yar taas oo daroogada la qaatay aan la aqbali karin.

"Concor Korintos" tilmaamaha loo isticmaalo (analogues - horumarsan beta-blockers - leeyihiin tilmaamaha la midka ah ee lagu ogolaan ee gelitaanka) waxa uu mamnuucayaa bukaanka qaba wadne joogsi in kaafi decompensated ba'an iyo chronic. Ha magacaabi dhaweynta daroogada ah ee burburka iyo shoog cardiogenic (xaalad ka dhashay cillad wadnaha). Mid ka mid ah ma ay qaadan kartaa beta-xanibaha for leexashooyinkaasi badan oo AV-tabinta (II, III degree AV-block) oo aan pacemaker ah. Sidoo kale sababta diidmada ah ee soo dhoweynta waa joogitaanka bradycardia (garaaca wadnaha (garaaca wadnaha) waa in ka yar 50 garaac / min.), Go'doominta Sinoatrial (sanka sii xumaanaysa Suu marayay xarunta sinoatrial). Daawada ahaan uu u bukaanka qaba Prinzmetal angina (misko weelashii qalbiga ku quudiyo, halka ST qeybta sare u qaadis) iyo sanka buka syndrome (SSS).

Ha qaadan "Concor Korintos" la hooseeyo cadaadiska dhiigga systolic (hoos 90 mm Hg Art..), In joogitaanka neefta qaab daran, kuwa la taariikh ah ee diiwaanka chronic obstructive pulmonary disease (COPD).

diyaarinta dheeraad ah "Konkor Korintos" Codsiga aan la aqbali karin in joogitaanka aan caadi ahayn in nidaamka wareegga dhiigga ka durugsan (inta badan ku saabsan tahay marxaladaha dambe) qaba cudurka Raynaud ee, pheochromocytoma (buro-caanood ama malignant APUD-system), iyo aysiidh dheefshiidka (wareeg ah dheelitirka acid-saldhig jihada of ashitada kordhaysa ay sabab u raasamaal ee alaabta acidic in unugyada by ay ku qabanaya ama la'aanta baabba ').

daawada iyo bisoprolol mugga la ogolaan karo

Sida laga soo xigtay tilmaamaha, ee beta-xanibaha waxaa la qaataa hal mar maalintii, fiican in aroortii, ka dib cuntada. Kiniinka "Concor Korintos" (waxa uu noqon lahaa daawada aan la isticmaalin - haddii ay tahay cudur ischaemic wadnaha, wadnaha chronic, ama hypertension) uma baahnid in aad calalin ama ku tuntay oo dhan liqo oo la qadar yar oo ah biyo ku maydhay.

Si ay u fuliyaan tallaabooyinka daweynta wadnaha chronic iyadoo la isticmaalayo daawada "Concor Korintos" waxaa lagu talinayaa in la fuliyo titration ee qiyaasta. nuxurka geedi socodka sida soo socota: inta lagu guda jiro 1 toddobaad st of qadarka helay beta-xanibaha eego bisoprolol waa 1.25 mg qiyaas 2-toddobaadkii la labanlaabayo (2.5 mg) 3 daqiiqo waa 3.75 mg. Inta lagu jiro muddada u dhaxaysa toddobaadka 4aad ilaa iyo dhamaadka qiyaasta 7-dii waa 5 mg maalin kasta Bisoprolol; 8 th toddobaadkii ilaa 11 th - 7.5 mg. Laga bilaabo toddobaadka 12aad aqbalay ugu badnaan 10 mg. qiyaasta loo baahan yahay (oo ay suurtagal tahay) si loo kordhiyo oo kaliya inay hubiyaan in hore sida caadiga ah loo dulqaatay iyo ma keeni dareen diidmo ah.

Halkan dushiisa - waa jawaabta su'aashan ka badan "Konkor" ka duwan "Konkor Korintos": duwanaansho labaad (2.5 mg bisoprolol) waa ku haboon si ay u bilaabaan tallaabooyin daweyn la xidhiidha dalalka wadnaha chronic joogto ah, halka ugu horeeyay (5 ama 10 mg) waa ka ku haboon daaweynta dayactirka.

Haddii mar uun, waxaa jiray sixitaanka dose of calaamadaha wadnaha ah, khubaro caafimaad ku talinaynaa qiyaasta saxda ah ee ku diuretics isku midka ah ama celiyeyaasha ACE. Markii muddo ka dib ka heli xaalada horumarinta, waxaa lagama maarmaan ah in ay sii wadaan geedi socodka of titration "Concor Korintos."

Therapy la daroogada this waa dabeecadda muddo dheer. baabiiyo oo ka mid ah beta-xanibaha waa in si tartiib tartiib ah dhaqan, gaar ahaan bukaanka qaba cudur wadnaha ah soo wajahay.

Xaddi badan: saamaynta iyo daaweynta

Tilmaamaha in daroogada mar walba uu weheliyo pill "Concor Korintos." Laga soo bilaabo, taas oo ay la qaado oo waxa jira sababo, waxa uu hore u tilmaamay. Hadda waxaan diiradda saari doonaa waxa la sameeyo haddii, sabab qaar ka mid ah, waa qiyaas badan oo aan la aqbali karin ayaa loo qaaday.

Symptomatology waa sida soo socota: koraya hypertension iyo bradycardia, bronchospasm, iyo jaaniska sare ah hypoglycemia bilawga laga yaabaa of wadnaha ba'an.

Cawaaqibta la helo qaadasho badan oo dad kala duwan oo kala duwanaan karaan huba. Malaha, kuwa ay dhibaatadu ka wadnaha oo shaqadiisa gaba, waa mid aad u xasaasi u ah xad-dhaaf ah qiyaasta lagula taliyey by dhakhtarkaaga. Go'aanka ugu fiican ee bukaan-socodka - si aad u aragto takhtar (haddii ay suurogal tahay in laftaada ayaa sidaas samayn) ama ka dhigi a "si degdeg ah". Iyadoo ku xiran baaxadda uu daroogada la aqbalay, dhakhtarka ayaa go'aamin doona tallaabooyinka in la qaado si ay u fududeeyaan xaaladda bukaanka.

hawlaha sidii deg deg ah inta badan lagu sameeyaa lavage gastric iyo soo dhaweynta ee absorbents (carbon shaqeysiin ama analogues ay). Dheeraad ah, ku xiran tahay xaaladda, daawaynta bisoprolol la joojin laga yaabaa in, iyo in muddo ah waqtiga loo baahan yahay, in isbitaalka ay noqon doontaa daryeel taageero ah iyo calaamadaha.

Tilmaamaha in "Concor Korintos" muujinaya in loo isticmaalo, dib u eegista caafimaadka iyo ilo kale oo aad macluumaad keenay dareenka of xirfadlayaasha iyo macaamiisha in bisoprolol waa adag ku filan kasteba si dialysis.

codsiga daliilka xun "Concor Korintos"

Sida ku dhowaad daroogo kasta, wuxuu awoodaa inuu bixiyo "Concor Korintos" waxyeelo of kala duwan xoogga on nidaamyada iyo xubnaha.

Iyadoo la tixgelinayo nidaamka wadnaha iyo, cabashooyinka ugu badan ee bukaannada ku dhacdo ee bradycardia iyo dhiig-karka (inta badan ee dadka ka cabanaya wadnaha chronic), horumarin karaan vasospasm. Ilaa xad ka yar waxa ay u badan tahay waa xadgudub AV-tabinta, decompensation wadnaha, Ulasocto barar durugsan.

Reaction in daroogada habdhiska u muuqataa yar fahmayaan oo ka koobnaan kartaa daal, madax xanuun iyo wareer, daal, qas hurdo, iyo caadada ee xillo. Aad ayay u yar, bukaanka ka cawdaan xanuun, qarow iyo dhalanteed. Xaaladaha intooda badan, calaamadahan aadan haysan coloration u daran iyo tijaabiyey kadib markii 1-2 toddobaad laga bilaabo daaweynta la "Concor Korintos."

Tilmaamayaasha loo isticmaalo iyo liiska sababo diirada dareenka dadka bukaanka ah oo leh taariikh ah macluumaad ku saabsan COPD iyo neefta, waxaa suuro gal ah ee bronchospasm. Marar dhif ah la hadal oo ku saabsan muuqaalka kore ee rhinitt xasaasiyad.

On qayb ka mid ah marinka dheef shiidka inta badan waxay keeni kartaa lallabo, matag, calool, shuban, dareen of qallayl xabka ku saabka afka. In ka yar inta badan ku hadlaan ku saabsan horumarinta hepatitis iyo bedesho in ensaymes beerka.

Waxa intaa dheer in kor ku xusan oo dhan, bukaanku uga warbixin rabshooyin muuqaalka iyo conjunctivitis (naadir), oo ku saabsan casiraad ku jiraa muruqyada kubka iyo tabar-dari muruq, xadgudub ku awoodba (aad u yar).

Of dareen diidmo oo xasaasiyadeed inta badan ee suurtogalka ah finan, cuncun iyo casaan.

"Concor Korintos" iyo uurka

Beta-xanibaha "Concor Korintos" inta ay uurka leedahay ayaa suuragal ah keliya xaaladaha halkaas oo lacagta la filayaa in hooyada uu caafimaad badan halista ka iman karta in ilmaha soo koraya.

Kasta beta-blockers (iyo "Concor Korintos" iyaga ka mid ah), yareeyo xoogga socodka dhiigga ee mandheerta iyo sidaas ayaa laga yaabaa in saameyn xun ku horumarka ilmaha ee utero. Haddii aad weli loo xilsaaray in ay helaan haweenka uurka leh dawooyinka, shaqaalaha daryeelka caafimaadka waa in si joogto ah loola socdo socodka dhiigga ee mandheerta iyo ilmo-galeenka, iyo sidoo kale si ay u dhawraan koritaanka iyo horumarka ilmaha. Haddii ay dhacdo in qodobada xun ee dumar iyo ilmaha waa in guurto on in kale, hababka kale ee daaweynta.

dhalashada ilmaha ka dib waa in si taxadir leh loo baaro. Inta lagu jiro 3 maalmood ee ugu horreeya ilmo hoos ugu dhigi kartaa heerka sonkorta ee dhiiga, sidoo kale waa suurto gal bradycardia (garaaca wadnaha oo hoos u) calaamadaha.

Sida loogu talagalay haweenka naas naas-nuujinta, macluumaad qoondaynta of bisoprolol la caanaha naaska ama ay ammaanka aan la heli karin ee ilmaha. Sidaa darteed, haddii loo baahdo, wuxuu heli tahay "Concor Korintos" in muddo this, waxaa lagama maarmaan ah in ay go'aan ka joojinta nuujinta.

daawooyinka la mid ah

In daroogada dhigooda "Concor Korintos" (way badan yihiin) waxaa inta badan ku yaal on qayb weyn ee firfircoon - bisoprolol. daawo Self la soo saaray ee Germany iyo Norway. daawooyin sida "Aritel" inta badan la isticmaalo oo ka mid ah dhigooda Ruush, iyo "Aritel Korintos", "Biprol", "bisoprolol-Prana". Inkastoo dambe waxaa laga heli karaa in dalal badan oo caalamka ah, "bisoprolol Teva" - Hungary, Israa'iil, "bisoprolol-nayaa" - Ukraine. Dhab ahaantii, analoogga ah si toos ah waa "Concor".

Dheeraad ah, ka inta badan loo isticmaalaa hab la mid ah oo la odhan karaa "Bidop" iyo "Bidop Korintos" "Biol" "Bisogamma", "Bisomor", "Kordinorm" iyo "Kordinorm Korintos", "Tiresias", "Niperten".

Guud ahaan, liiska analogues (micne ah) waa arrin ballaaran oo kala duwan, laakiin si ay u xaliyaan su'aasha ah waxa uu u bedelo "Concor Korintos" is la aqbali karin. Doorashada saxda ah ee medicament ah in bedel iska leh oo kaliya in ay dhakhtarka xaadirka ah.

Dhexgalka daroogooyinka kale

On waxtarka wanaagsan iyo tolerability ee beta-blockers saamayn ku yeelan kara isticmaalka labada daroogada waqti isku mid ah. Iyadoo la tixgelinayo daroogada "Concor Korintos" (tilmaamo loo isticmaalo, shaqaalaha daryeelka caafimaadka dhabta ah iyo bukaanka xaqiijin reaction sida a) dulqaad dhici kartaa xataa haddii la mid ah daroogada saamayn mabda 'ayaa loo qaaday iyada oo qadar yar oo ah waqtiga kasta oo kale.

Dheeraad ah, bukaanka qaadanaya bisoprolol, waxaa lagama maarmaan ah in la ogaado waxa xasaasiyadda for immunotherapy ama doodii baaritaanka maqaarka keeni kara horumarinta falcelin daran systemic xasaasiyad ama anaphylaxis. Waxay keeni kartaa shoog iyo codsiga isku mar wakiilada bisoprolol iyo duwan iodinated maamulka xididka.

Kaadida, daroogada sympatholytic iyo antihypertensive kale, bisoprolol lala isticmaalaa, waxay keeni kartaa xad-dhaafka ah hoos u cadaadiska dhiigga.

murugada tetracycline, jirada dhimirka, daawada dajiyaha iyo daroogada hypnotics ku tuuji habka dhexe ee neerfayaasha. Saamaynta of insulin ama daawooyin kale oo la mid hypoglycemic maamulka afka inta lagu guda jiro daawaynta medicament ah "Konkor Korintos" kordhin karta. Symptomatology horumarinta hypoglycemia (tachycardia gaar ahaan) waa la baabi'iyay karaan ama dadan.

Maxaa si ay u eegaan, waayo?

Dadka "Concor Korintos" waxa lagu qoray codsiga waa la'ogolaan karin on iyaga u gaar ah in ay kala go'do daaweynta ama in la beddelo qiyaasta lagula taliyey oo aan marka hore la tashan dhakhtarkaaga. Xaaladaha noocaas ah waxaa suurto gal sii xumaanaysa ee dhaqdhaqaaqa wadnaha. Tani waa run gaar ah bukaanada qaba cudurka halbowlaha wadnaha. Haddii ay lagama maarmaan noqoto si ay u joojiso daawada daaweynta "Concor Korintos", soo saaraha waxay ku talineysaa in aad taas samayn, si tartiib ah u yareeyo qiyaasta.

At bukaanka sigaarka waxtarka beta-blockers ka hooseeya kuwa aan cabin sigaarka.

Kuwa xirtaan contact lenses, waa in aad maanka ku hayo in beta-blockers waxay sababi karaan hoos u wax soo saarka ee dareeraha jeex.

Haddii bukaanka uu yeesho baahan yahay qaliin la doorto, qaata "Concor Korintos" Waa in ay joojiyaan qaadashada yar oo dhan ma ka badan 48 saacadood ka hor suuxinta guud. Haddii qalliin degdeg loogu baahan yahay, iyo bukaanka ayaa hore u heshay a beta-xanibaha, suuxinta guud waxaa lagama maarmaan ah in ay doortaan daroogo saamaynta inotropic negative yar.

Gebogebadii waxaan doonayaa in la yidhaahdo wax kasta oo u lahaa in ay dawo akhrinta "Concor Korintos", dib-oolnimada sare on qayb ka mid ah bukaanka iyo shaqaalaha caafimaadka, go'aanka magacaabidda magaca qofka kasta oo gaar ah ayaa la micno ah "Concor Korintos 'oo aan wax beta kale xanibaha, waa iska leh oo kaliya in ay dhakhtarka xaadirka ah.