Tilmaamaha loogu isticmaalo, ah analog "Cefotaxime" iyo dib u eegis

"Cefotaxime" (tilmaamo loo isticmaalo, xeerarka xisaabinta qiyaasta aan fiicnayn, iyo sidoo kale analogues ugu caansan waa la hoos ku siin doonaa) waa antibiotic casriga ah semi-dardaro. Waa adkaysi u beta-lactamases iyo waa firfircoon ka dhanka ah labada sheyga garaam-positive iyo garaam-negative. Hab dareen-celin lagmamaarmaanna u sabab u ah xakamaynta ee awoodda ka mid ah qaybaha la xidhiidha geedi socodka dabiiciga ah ee ka dhaca in xuub gacanta of wareer ah.

Daawada waxaa jirka galo, si ula kac ah wada baabbi'iyaa kan peptidoglycan xigay cruciform, sidaas darteed lagama maarmaanka u ah bakteeriyada si loo hubiyo joogtaynta ee derbiyada dabiiciga ah. Sida la og yahay, unugyada iyo inhibitors maaddooyinka cell gardarraloowna laastikada - taasi waa bartilmaameed u fudud.

Form sii daayo

medicament "Cefotaxime" The (irbado Buugga iyo infusions soo bandhigaysaa sida circuit bixinta kaliya ee suurto gal ah walaxda firfircoon) waxaa bixisey in suuqa dawooyinka ee budada cad ama jaalle ah, taas oo u adeegta sida ku saleysan diyaarinta of xal. Tani waa waxa loogu yeero ampoules duro.

Asalka ah 10 fijaan mugga ml sameeyey oo muraayad. The joogo reagent mass dhabta ah ee unit ka mid ah wax soo saarka ku xiran tahay buuxintii ee maxalka furta (0.5, 1.0 ama 2.0 grams).

seenyo pharmacokinetic

Waa in si deg deg ah in la ogaadaa in aan kasta oo analog "Cefotaxime" ayaa guryaha pharmacokinetic la mid ah sida asalka ah. Gaar ahaan, haddii aan ka hadlo heerka of nuugista of qaybaha laga duray, nuugista ee wakiilada, kuwaas oo, idinkoo xukumaya by ee comments of practitioners badan, waa wax badan ka dhaqso badan nuugista hore ee isla weli "Duataksa" ama "Tsetaksa". "Dhacdooyinka" Sababta been Britain habaysan hore tijaabada. Khubarada in jawaabaha ay xoogga saaraan xaqiiqada ah in generic Indian kor ku kooban "nadiif dawooyinka" ee foomka of taagayo cephalosporin adag taas oo si weyn loogu talla-shiid ee maaddooyinka kale.

Waxaa la ogaaday in "Cefotaxime" (akhrinta ku dhisnayn guide rasmiga ah in ay daroogada ka siiyo, la baabi'iyo jaaniska u socoto in joogitaanka dhiig) muujinayaa heer sare ah ku qabanaya borotiinka plasma, halka muddada saamayn microbicidal kala duwan 11-12 saacadood gudahood. Isagoo wakiilka ah laga bilaabo Isbadal waxaa si siman ee jirka ku jira, oo ay ku jiraan lafaha (fiirsashada ugu badnaan waxaa sidoo kale lagu arkay ee myocardium iyo xameetida).

Walaxda ugu weyn ee kaas oo ah guulaysta celiyaha mandheerta kaasi oo uu noqdo qayb muhiim ah oo ka mid ah pericardium iyo dheecaanka lafdhabarka. Celceliska bar-nolosha ee faleebo faleebo xididka kama badna hal saac la irbado duridda - mid ka mid ah boqol-siddeetan daqiiqo. Kasta oo yareysey raasamaal ah waxyaabaha aan la calaamadeeyay - qayb ka mid ah qaybaha soo wada saxarrada ee bile iyo kale (oo ku saabsan 90%) - kaadida. Xaalada danbe, saamiga metabolites firfircoon ku koobnayn 20-30% qiyaasta maamula, i.e. ku saabsan 70% ka mid ah xalka jidhka ka tago oo aan lagu beddelka dhismaha.

Tilmaamayaasha waayo,

wakiilada waxaa si wanaagsan loo habeeyey sida xanibaha oo ah hawlgaladii faafa iyo bararka socda sheyga, gaar ahaan xasaasi u ah cefotaxime. Iyo caddaymo ah ma aha oo kaliya waxbarashada clinical - gabagabo la mid ah waxaa lagu sameyn karaa ka dib markii reading ku dib u eegista wanaagsan oo tiro badan posted on website-ka, theme of taas oo ah daroogo ku ool ah si ay ula dagaalamaan wareer ah. tallaabo Front pharmacological daroogada in ku filan oo ballaadhan, laakiin marar badan "on hortooda" chronic dayrta ama cudurada kelyaha ba'an dhaca iyo kaadi mareenka, iyo sidoo kale cudurada neef-mareenka sare.

Waa inaan sheegaa in, xataa haddii aqoonsi buuxda ka kooban ee ah analog "Cefotaxime", in "Tsefasin" ama "Tsetaks" in aan la magacaabin in ay isticmaalaan oo ku salaysan shuruudaha kor ku xusan. Xaqiiqdu waxay tahay in dad badan oo u muuqdaan in ay xabbo oo kaliya "nuqul qaraabo 'model lagmamaarmaanna u ah hannaanka asalka ah ee dhaqanka, oo sidaas daraaddeed card daawada saxda ah in tixgelinayo jadwalka iyo qiyaasta" double "waa in loo xisaabiyo ku takhasusay khibrad leh.

Shayga asalka ah waxaa lagu talinayaa in la isticmaalo haddii:

• bukaan qaba cudurka cudurada ka mid ah habka neefsashada ah qaab pneumonia, malax ama boronkiitada, iyo antibiotics kale ma keeno natiijo la doonayo;
• bukaanka waa cuslaatay bakteeriyada meningitis horusocod ah,
• imtixaanada xaqiijiyay joogitaanka endocarditis;
• in muddada postoperative ayaa awoodi waayay in ay ka fogaadaan dhibaatooyinka qaab burburinta focal of maqaarka iyo / ama xuub xubnaha muhiimka ah;
• wakiilada faafa degay ee lafta, iyo irbado duridda daawooyin-micne lahayn saameyn aysan iyagii;
• Gram-negative ama garaam-positive boogaha gubashada daalaeday iyo caabuq kaga xanaajiyeen qiyaasta (ilaa sepsis);
• waxaa loo baahan yahay tallaabooyin ka hortag ah.

khubaro Independent u muuqdaan in ay aaminsan yihiin in uu jiro wax yar analoogga kasta "Cefotaxime" awoodaan si ay u muujiyaan dhaqdhaqaaqa wanaagsan si cad qaba cudurka faraxnay. Waxaa xusuus mudan in ku tilmaamay asalka ah, ku xiran codsiga joogto ah, hawsha si fiican u qabsadaan si wanaagsan (comments, ka go'an in Gudigga koorsada-daweynta, bukaannada waxaa la geeyaa on forums ah).

Isticmaalka iyo qiyaasta

"Cefotaxime" edbinta (irbado, sida ay dhakhaatiirta iyo bukaanka qaarkood ma yihiin sida wax ku ool ah sida dejinta a walax) waxaa u taagan sidii dagaal ficil-oriented ah cudurrada bakteeriyada daran xushay antibiotic. Sida hore u soo sheegnay, waxaa jira saddex wareeggeedii reagent bixinta: by galiyey faleebo ama jet, iyo sidoo kale iyada oo loo marayo duridda. xeerarka Midaysan diyaarinta dheecaanka ka shaqeeya in aanu jirin, sidaa daraadeed waxa muhiim ah in la ogaado in horay qaabka maamulka ee daroogada.

Manufacturer, gaar ahaan, waxay ku talinaysaa socda geynta this:

• for a irbadaha / th: 1 garaam oo ah budada in la kala diri ee 4 ml oo biyo ah, lidocaine ama novocaine;
• la isku duro xididka: 1 g oo ah walaxda loo baahan yahay si ay u milmaan in biyo nadiif ah (4 ml);
• waayo, / in galiyey: dhalada leh laba garaam cefotaxime u baahan tahay inaad ku dar 100 ml oo ah NaCl (0,9%) ama glucose isla boqolkiiba shan.

Delivery reagent time:

• at / m irbado: 5-10;
• at / hordhaca jet ah: 5.3 min;
• marka la dejinayo walax: 50-60 min.

Xisaabinta qiyaasta isku dheeli tiran oo balan dhismaha dhaweynta fiicnayn waxaa lagu fuliyaa si gaar ah. Waxaa la tixgelinayo da'da bukaanka iyo miisaanka jidhkiisa ah, iyo sidoo kale nooca cudurka iyo marxaladda ay horumarka. Intaa waxaa dheer, beddelka ku sameeyey taariikhda daweynta.

Si kastaba ha ahaatee, tilmaamaha hase ahaatee waxay bixisaa macluumaad ku saabsan heerka celceliska codsiga "cefotaxime" daroogada. Cirbadaha (sida budada la badhxay, ku tilmaamay si faahfaahsan kor ku xusan, laakiin, si xiisa leh, ku dhowaad dhammaan jawaab-celinta waxaa ku badan fikradda ah in la duray - habraaca waa arrin xanuun badan oo xun, xitaa dhan talooyinka soo saaraha), gaar ahaan, waxaa lagu qoray xaaladaha dhibka badnayn, jejebiyeen 4-12 saacadood iyo dhoos keli ah 1-2 garaam. Wixii muhiim ah oo subcritical muhiim ah in xaaladood / sal-dhigida (at heerka of 2 g 4 saacadood kasta, laakiin aan ka badnayn 12 g / maalintii).

Takhaatiirta carruurta ee mudada doorashada hanuuniyey by miisaanka dhallinyarada bukaanka jidhka iyo guud ahaan dareen-celin jirka ( "standard" - laba ilaa lix irbado jet, 50-180 mg / kg).

waxyeellooyin

Marka uu u xilsaarayo a medicament "Cefotaxime" (irbado ratings la mid ma aha sasabasho miidhan ah sida faleebo faleebo, tan iyo markii hordhaca / m waxaa inta badan la socda xanuun, waayo, Sababtaas darteed, sida a "dareeraha" waxaa badanaa lagu procaine ama lidocaine) ma laga saari karo qaybaha tallaabo atypical nidaamka iyo xubnaha bukaan-socodka.

ogolaan karo:

• "Jawaabaha" xasaasiyad qaab baaxad weyn oo urtikaria, anjioedema ama candidiasis;
• dhibaatooyinka heerka of mareenka caloosha iyo mindhicirka (matag, yalaalugo, dhif - joonis cholestatic);
• xanuunada ee dhiigga (hoos u dhac ku dhiig xinjirowga, anemia hemolytic iyo m. p.).

cawaaqibka xad dhaafka ah

kororka xad-dhaafka ah ee looga baahan yahay maalin walba waa ben la dysbiosis iyo encephalopathy; Waxa kale oo ay u badan tahay haya'ad xanaaq iska maqaarka.

Hawsha aasaasiga ah waa in la hubiyo in stop bixinta reagent galay jidhka. tallaabooyin dheeraad ah loo baahan yahay si loo xasiliyo gobolka qabanaya leh isticmaalka waxa ka sameysan pharmacological desensitizing (la socodka uu dhakhtarka).

Sida laga soo xigtay sababo saaraha

Sida laga soo xigtay warbixin ka siiyey war ah oo rasmi ah, "cefotaxime" (irbado carruurta, sida caadiga ah laguu qoray ka dib 30 bilood jirka ah, ka hor inta aanay u gudbin I / galiyey) waa in aan la isticmaalaa:

• inta aad uurka leedahay,
• diidmo in maaddooyinka;
• dhiig furitaanka iyo xidhitaanka ah;
• Haddii dhacdooyin of enterocolitis hore u matalayay ee taariikhda.

isdhexgalka daroogada

In guide asalka diiradda on xaqiiqada ah in xal kale xaalad kasta waa in aan la isla maamulo (oo ka mid ah qalab caafimaad) oo leh awood antibiotic "cefotaxime".

Cirbadaha (iyadoo la isticmaalayo faleebo eego dhexgalka pharmacological la qaybaha daroogada kale, waa ma ka duwan duro / m ah), gaar ahaan, ka cadhaysiinina karaa dhaawac kelyaha, haddii ay "is bahaysi" qeexay diyaarinta qabtaan aminoglycoside kasta ama lagu durayo loop a. Taa baddalkeeda, interlocks dheecaan embriyaha si adag hor joogsada nidaamka bixitaanka reactant siiyey oo wuxuu kobciyaa kordhinta ay fiirsashada.

Isku darka leh antiplatelet sidoo kale loo baahnayn sababtoo ah khatarta ah ee dhiig-bax.

booska waxbarasho gaar ah

"Cefotaxime" (analogs tableted, sida ay dib u fiiriyaan oo comments waa wax ku ool ah ka yar) mararka qaarkood dhirfinaya been muunad Kumbusa iyo "spoofs" falanqaynta kaadi glucose runta ah.

Marka dhanka Electricity-therapy muddo dheer ka kooban qaybaha kala duwan ee dhiigga Waa in la fuliyo oo aan ka yarayn 1 time in 10 maalmood.

Oo wakhtigii hore ee daaweynta meesha kama saarayso qaab daran shuban. Iyo, dabeecad ahaan, analog sida "Cefotaxime" (ee carruurta da'doodu ka yar tahay 12 sano gudbiyo "keyd" laguma talinayo), sida "Fagotsef" sawirka caafimaad oo la mid ah inta badan caadi ka yar yahay.

Cabitaanka khamriga inta lagu guda jiro daawaynta ku salaysan reagent ah gebi ahaanba la mamnuucay.

Taas oo dhab ahaan le'eg oo lagu "Cefotaxime" talinaynaa isticmaalka khubaro madax banaan?

Comments on "Sefotake" iyo "Tsefantrale" sida isku micne ah ee alaabta ku tilmaamay pharmacological isku qasan. Siidi by dib u eegista ah, ayaa qastigoodii dhaqtarka inta badan qoraal soo baxay jiho qoro si ay u iibsadaan isku mid ah "Tsefabola" ama "canshuur-on-ka dalab." Si kastaba ha ahaatee, qaar ka mid ah bukaannada u muuqdaan in ay aaminsan yihiin in saameynta ku daweyn of shay-baarka ku xusan si liidata ku qeexan iyo jaaniska of horumarinta reactions atypical sineyn sare.

Marka forums ah su'aasha la sara kiciyaa sida ay u riixdaa "cefotaxime" aan yeelin, dhakhaatiir badan talin:

• imtixaanka, oo aanay jawaab u tahay in ay qayb raaxo gaar ah (haddii syndrome waa joogto iyo procaine qasi budada, ka dibna ay jirto sabab lagu rumaysan in raaxo - natiijo ah oo xasaasiyad halkii ay saamaynta tooska ah ee walax);
• raadiyo kale hufan.

Falanqaynta of fikradaha muujinaysaa in inta badan "ixtiraam" dhexdooda micne ah abaal "Lorax The." Si kastaba ha ahaatee, ka hor inta aan bedel mid reactant in kale waa in had iyo jeer la tasho dhakhtar takhasus u leh.