Lymphomas T-cell: nooc, calaamadaha, cudurka, daaweynta iyo saadaasha

lymphomas T-cell inta badan laga helay ee dadka ka buka da 'weyn, laakiin dhallinyarada iyo carruurta ayaa sidoo kale u nugul cudurka. Oo markaasay nimankii wax ku xanuunsado waxaa inta badan haweenka ka.

Waa maxay lymphomas T-gacanta

Lymphoma - a nabar malignant unugyada lymphoid iyo xubnaha kale. In the case of lymphoma T-cell, cudurka saamayn ku maqaarka iyo dheecaanka qanjidhada (ie waa qof epidermotropny). Waxyaabaha asaasiga ah in ay lug ku leeyihiin dhacdo ee neoplasms yihiin T-limfosaytis (unugyada caadiga ah siiyaan wax ka qabashada difaaca oo ku filan). lymphoma T-cell (sawirka hoos ku matalayay) la abuuri karaa oo sabab u ah raasamaal ee unugyada bahal xubno gacanta.

Sababaha iyo qodobada saacidey

• hiddo
• Immunodeficiencies.
• gaadhista sii dheeraaday in arrimaha loo kasin: shucaaca UV, walxaha kiimikada dagaal badan.
• Age arrin (bukaanada waayeelka).
• Joogitaanka fayrus ee u shaqeeyo (HIV, Epstein-Barr, hepatitis C, B, virus T-lymphocyte), cudurka xiidmaha.
• Joogitaanka Isbedelo in xubin badalida habka difaaca, xubnaha iyo unugyada, ballan therapy jirka.

Dhamaan arimahan waxaa loo sahlay laga yaabaa by (siday u kala horreeyaan, cadhaysiinina horumarinta cudurka), stress, nafaqo-xumo, overloads neerfayaasha, failure in ay u hoggaansamaan taliskii nasasho iyo shaqada.

kala soocidda

• maqaarka lymphoma T-cell. lymphomas la mid ah sida caadiga ah loo horumariyo sabab u ah Isbedelo kala duwan ee limfosaytis T, taasoo keentay in isku dhufashada caasiyoobay doonana iyo, sidaas awgeed, iyaga khusaysaa in lakabka ah ee epidermis. Lagu gartaa foomka firfircoon ee lymphomas dhacdo finan polymorph (huurada, burooyinka, Wasaqda, finan). Oo bukaanka ugu horeysay ka caban of dhacdo of qolof ama cuncun baro, ugu danbeyn ekaysiinaya dabar, oo markii danbe ee Axdigu burada.
• Durugsan lymphoma T-cell. Aragtidani waxa ay ka mid ah oo dhan lymphomas in ay yihiin T-cell ama asal NK-cell (neoplasm of T-unugyada aan weli qaan gaadhin iyo leukemia T-lymphoblastic marka laga reebo). Marar badan, lymphomas dhacaan leh lesions dhiig, maqaarka, dhuuxa lafta iyo xubnaha gudaha, iyo qanjidhada ah, waasac dambidhaafkiisu isbedel infiltrative arkay.
• Angioimmunoblastic lymphoma T-cell. Waxaa muujiyey sida dhagixiina way unugyada lymphoid (inta lagu jiro baaritaanka histological of mergiga) unugyada immunoblast iyo plasma, la Isbadal ku xiga dhamaystiran oo qaab-dhismeedkooda iyo formation of xididdada dhiigga aan caadi ahayn.
• T-cell Lymphoma lymphoblastic. Novobrazovanie, kaas oo ku salaysan yahay cilladaha unugyada T. unugyada T ma u hagaagaan, oo ay xuduntii uu noqdo caadi ahayn ee qaabka, waxay si dhakhso ah iyo dhuujinayso dhici. Kala kulantay noocan oo kale ah lymphoma waa dhif. Haddii aad la kulanto cudurka kala duwan hannaanka la mid ah la leukemia ba'an.
• lymphoma T-cell Non-Hodgkin ee. Waxay ka dhigan tahay koox weyn oo burooyinka in ka kooban yihiin baaluq T-limfosaytis oo aan la xidhiidhaan cudurka Hodgkin (i.e., cudurka Hodgkin). Ka tirsan kooxdan waxaa go'aamiya baaritaan histological (la chlamydia ee Diyaarinta ogaado xubno gacanta gaar Berezovsky-Sternberg at lymphomas non-Hodgkin yihiin ma jiro).

stage horumarineed

1. Guuldaradan ayaa ah mid ka mid ah Guntin lymph.
2. faafidda buro laba qanjidhada oo ku yaal hal dhinac oo diaphragm ka.
3. dhismayaasha lymph Multiple labada dhinac ee diaphragm ka.
4. mergiga iyo xubnaha gudaha, jiritaanka metastases in kelyaha, dhuuxa lafta, beerka ama xubnaha of mareenka caloosha iyo mindhicirka.

calaamadaha Guud

joogitaanka ama maqnaanshaha of daliilka kiliinikada gaar ah ku xiran tahay nooca burada iyo goobta. Si kastaba ha ahaatee, waxaa jira calaamado in ay yihiin asalka ah ee ku dhow oo dhan lymphoma T-cell:

• Dhidid habeenkii.
• miisaanka Rapid khasaare waa sabab.
• fungoides Mycosis.
• waxqabadka fasalka Low in heerkulka jidhka.
• daal joogto ah iyo arxandarro.

fungoides mycosis

fungoides Mycosis - mid ka mid ah daliilka ugu badan in sifaha lymphoma T-cell. Waxaa laga helaa toddobaatan boqolkiiba bukaannada qaba cudurkan, iyo waxay leedahay saddex nooc: classical, Wariye iyo erythrodermic.

fungoides mycosis classical maraa saddex marxaladood ee horumarinta:

• Erythematous - ka astaamaha caafimaad oo la mid ah cudurka psoriasis, cambaarta iyo wixii la mid ah. Bukaan-socodka sheegaan joogitaanka Wasaqda qaab gadood ama wareeg ah, oo leh geesaha fiiqan, ee tirada kala duwan, iyadoo midabka casaan-buluug iyo dusha qolof. xubno noocan oo kale ah ayaa inta badan ku yaal on wajiga iyo jir, si tartiib ah u sii kordhaya tirada iyo marayay qaybo kale. lesions noocan oo kale ah aadan ka jawaabin daaweynta oo aan la qaban karaa wakhti dheer ah, ama si lama filaan ah baaba'aan. Waxaa intaa dheer, Wasaqda lagu dari karaa cuncun, taas oo aan la joojiyay by hab caadiga ah.
• infiltrative aan tooska ahayn - dhacdaa dhowr sano ah bilawga ka dib. In meel of dabarrada Wasaqda kor ku xusan oo leh xuduud cufan, fekrado ama nepravilnymi laakiin cad, iyo guduud la hoolmay dushiisa. Ugu site oo ka mid ah dabar maqan yihiin meelaha of brown ama maqaarka atrophy. korodhka cuncun, waxa uu noqonayaa mid loo dulqaadan karin. Waxaa jira miisaan degdeg ah khasaaro iyo qandho, Lymphadenopathy waxaa laga yaabaa in la joogo.
• Buro - on-site ama dabar on maqaarka waxaa si aan loo beddelin muuqaalka kore ee cufan casaanka iyo jaalaha xanuun foomka buro spherical ama wax yar qaab simay, eg hat likaha ah. Dhexroor ee qaababka sida u dhaxeysa hal ilaa labaatan milimitir, iyo tirada laga yaabaa kala duwan. Marka burada waa la wada baabbi'iyey, boogaha daran sameeyay in ay meel, si qoto dheer ee oo ay gaari karaan fascia ama lafaha. Inta badan saameeyaa caajisnimo ah, qanjidhada, sambabada iyo beerka. sarkhaan Narostaet iyo daciifnimo. Bukaan-socodka dhiman ee wadnaha, amyloidosis, pneumonia.

foomka Eritrodermicheskoy waxa lagu gartaa ah ee cuncun daran narostaet, casaan iyo barar, muuqaalka kore ee confluent dhibco erythematous-squamous, hyperkeratosis ee ay calaacalaha iyo Timir, iyo sidoo kale timaha. Ballaadhi oo dhan qanjidhada in axillary ah, inguinal, bawdeedka iyo meelaha cubital. Marka waxaa la helay ay plotnoelastichnye xirmooyin lymph taataabasho xanuun ma soldered si nudaha ku hareereysan (maqaarka). Lihodradka arkay (ilaa 39 degrees), miisaanka oo yaraada, dhidid habeenkii ah iyo daal. natiijada dilaaga ahi waa suurto gal ah marka uusan ku biirin sii sarkhaan iyo wadnaha oo shaqadiisa gaba.

In joogitaanka foomka Wariye on maqaarka caafimaad waxaa jira dabar badan, ugu danbeyn isuna harater malignant. Dhimashada dhacdaa in bukaan sannad gudihii.

daliilka Clinical of lymphomas cutaneous

lymphoma T-cell maqaarka badanaa ka dhacdaa loogana hortegi ee daaweynta mudada dheer jira iyo habboonayn cudurrada maqaar. Cadhaysiinina ay dhacdo herpes karaan fayraska, shucaaca, gubto iyo wixii la mid ah. lymphomas la mid ah ka dhacaan laba marxaladood: (marka lesions maqaarka waa natiijada dhexgalka lymphocyte oo ka mid ah xubnaha gudaha) aasaasiga ah (nidaamka waxaa ku kooban in maqaarkaba ah), dugsiyada sare.

Calaamadaha ugu muhiimsan waxay kala yihiin:

• Finan maqaarka Polymorphic.
• Kacaya cuncun.
• Joogitaanka yar, xubno ka guri qaab nodular.
• Imaansho dabar hurdi, markii danbe ekaysiinaya meelo ka mid ah hyperpigmentation iyo atrophy (marka foomka huurada).
• Sawirka caafimaad oo u eg psoriasis (at nooca melkouzelkovoy).
• Qallayl, barar, casaan iyo qolof ee maqaarka (nooca erythrodermic cudurka).

Symptomatology of lymphomas durugsan

cudurka Clinic waxay ku xiran tahay marxaladda iyo nooca habka bahal ah.

Lagu gartaa koror ah unugyada lymphoid ee gobollada qoorta, gumaarka iyo axillary.

Bukaan-socodka ka cawdaan dhidid xad-dhaaf ah, miisaanka daran khasaare, rabitaan la'aan cunto, tabar guud, qandho, iyo in joogitaanka beeryarada balaartay iyo beerka (taas oo ah wax caadi ah) - by neefta oo ku qabata, qufac soo noqnoqda iyo dareen u tiiraanyooday in caloosha.

Baadhista xanuunada

• Inspection, ururinta cabashooyinka iyo Oncologist anamnesis.
• dhiig Guud iyo falanqaynta kaadida.
• Kiimikada noole dhiig, iyo sidoo kale baaritaanka unugyada fayrusyada hepatitis ah.
• biopsy A of Guntin ku lymph burburay (taas oo kuu ogolaanaya in aad si loo xaqiijiyo ogaanshaha lymphoma T-cell).
• US.
• MR.
• CT.
• jirka Onkoskrining.
• Daraasad Immunofenotipirovannoe.
• falanqayn hidde kelli.
• Falanqaynta Cytogenetic.

therapy

Daaweynta lymphoma T-cell waxay ku xiran tahay qaab iyo marxalad geedi socodka.

Tusaale ahaan, ee fungoides mycosis stage erythematous therapy anticancer gaar ah aan la magacaabay, iyo corticosteroids dibadda ah iyo interferon ayaa loo isticmaalaa.

The daaweynta anti-buro waa in ay fuliyaan chemotherapy iyo radiotherapy.

Iyadoo la tixraacayo nooc ka mid ah cudurka (caajis, dagaal badan, oo heer sare ah mintid) waxaa lagu go'aamiyaa oo dhererkeeda iyo Halabuurka ee daaweynta, iyo dhaqan celinta.

lymphoma caajis aan la daawayn, laakiin kaliya si joogto ah u arkay haddii habka socdo, xeeladaha ka beddelo.

In daaweynta noocyada dagaal isticmaalka isku dhafan oo ah daawooyinka kiimikada, iyo Rituximab (antibody monoclonal).

Marka ay timaado in lymphomas heer sare ah mintid, daawo loo isticmaalo in lagu daaweeyo leukemias ba'an.

Marar badan, chemotherapy weheliso badalida unugyada asliga ah.

Si kastaba ha ahaatee, daaweynta ugu waxtarka badan ee lymphoma waa in ay sameeyaan daaweynta iyo soddon shucaac ah (sida ku cad Elekta YAQINSAN), iyo ka dib markii la helo wakiilada kiimikada.

Dhibaatooyinka qaata wakiilada kiimikada ka mid noqon kara: sambabka, naasaha, iyo wixii la mid ah. Dawaynta ilayska keeni laga yaabaa by horumarinta atherosclerosis wadnaha.

Ka dib markii daaweyn guul waa dhaqan khasabka ah.

lymphoma T-cell: Saadaasha

• Marka la ogaado waqtigii cudurka (marxaladda hore) iyo shaqo ee heerka ku filan daaweyn shan sano badbaadada waa shan iyo siddeetan boqolkiiba, iyo dadka bukaanka ah ee carruurta - in sagaashan boqolkiiba.
• Marka laga lymphoma angioimmunoblastic Saadaasha niyad jab. Filashada The nolosha celcelis ahaan in bukaanka qaba cudurka noocan oo kale ah waa uun laba iyo badh - saddex sano. Heerka badbaadista of kaliya saddex meelood hal meel dadka bukaanka ah waxay leeyihiin muddo shan sano ah.
• In joogitaanka T-lymphoblastic foomka saadaal ku xiran tahay joogitaanka / maqnaanshaha dhaawaca ah ee dhuuxa lafta. Haddii dhuuxa lafta kama beddelayso, natiijada badanaaba waa wanaagsan. Haddii kale, laga fili karo horumar ee boqolkiiba bukaannada labaatan weel oo keliya.
• avium saadaal iyo badbaadada likaha waxay ku xiran tahay qaab iyo marxalad geedi socodka. Sidaas darteed, markii bar badbaadada foomka - ilaa iyo toban sano, iyo saadaasha ah allifey in ay dhacdo goysiga ah pneumonia, iyo wixii la mid ah; foomka eritrodermicheskoy sorovozhdaetsya ku biiro dhibaatooyin kala duwan oo keentay in dhimashada dhacdaa laba gudahood - shan sannadood; halka foomka oo madaxii laga jaray ee saadaasha miskiin ah, dhimasho dhacdaa sannad gudihii.