Daawada "Avastin" in indhaha: dib u eegista, tilmaamaha loo isticmaalo iyo halabuurka

In daawada, waxaa jira xaalado marka qalabka loogu talagalay daawaynta cudurada qaar ka mid ah, ay umuujiyaan natiijooyinka wanaagsan ee daaweynta dadka kale. Tani waxay dhacdaa iyada oo sababtu tahay tijaabo badan ka hor daroogada gaadho macaamilka. Tani waxay dhacday daroogada horumartay ee daaweynta ee burooyinka kansarka, xaq "Avastin". In indhaha iyo dib u eegis of daaweyn caafimaad uu ku qasbay in uu ka fekero, waayo waxa ujeeddada iyo waxa cudurka fiican in la isticmaalo daroogada.

"Avastin"

Lumista aragga - mid ka mid ah murugta leh ee satalayt gabowga aadanaha. Ilaa dhawaan, inta badan habka isha gudahood ahayd arrin ay adag tahay in la xakameeyo, laakiin sannadihii la soo dhaafay in indhaha soo helay in loo ogol yahay si looga hortago in horumarinta cudurada halista ah ee indho la'aan.

Ujeedada this, kooxaha kala duwan ee daroogada waxaa loo isticmaalaa, tusaale ahaan, loo isticmaalo si guul weyn oo lagu daweeyo kansarka wakiilka "Avastin" ee indhaha. bukaanka Reviews xaqiijin xaqiiqda ah in daroogada ayaa Heer sare ah ee hufnaanta. Laakiin si ay u fahmaan sida ay tahay wax ku ool ah, waxaa lagama maarmaan ah in la tixgeliyo hab ay of nno isha.

hababka horumarinta cudurka

Lumista aragga waxaa sabab u ah kororka aan caadi ahayn ee qalintaanka dhiig. Shaacbaxaya weelal cusub koraan iyada oo xuub, khalkhal-dhismeedka ee isha. Waxaa intaa dheer, tiro badan oo ka mid ah xididdada dhiigga oo dood hemorrhage soo noqnoqda, taas oo laga dareemi karo nin iyo saamayn ku tayada aragga. Jebiyey nabarradii qalintaanka, iyo tiro badan oo ah unugyo ee xuubka ileyska xasaasiga ku jebiyo habka of quudinta isha.

markan la oran karo waa biloowga of aragga ah. Muhiimsan, aragti horumarinta cudurada degaaankaaga, sida aan gabi ahaanba laga badiyay, sida durugsan sida caadiga ah sii raagayaan. Si kastaba ha ahaatee, tayada nolosha si weyn hoos.

In kasta oo xaqiiqda ah in sawirka cudurka uu u muuqdo mid aad u nixiyay, iyadoo cudurka waqtigii of cudurada waa la joojin karaa in nafo la tusay. Ujeedada this, iyo codsan "Avastin" daroogada ee indhaha. Reviews bukaanka iyo dhakhtarrada ayaa xaqiijiyay statistics fiican.

Sidee daroogada

"Avastin" waa wakiilka anticancer ah, waxaa loo isticmaalaa in kansarka sanado badan oo ay muujinaysaa natiijooyin fiican. Sida ay u shaqayso - geeddi-socodka ah ee ka xanibeen in ay sameeyaan koritaan unugyada, qeybinta unug aan caadi ahayn. Sidaa darteed, joojiyey koritaanka xididdada dhiigga cusub, waxa ay meesha sababaha cudurka laftiisa.

Muddo dheer waxaa jiray shaki ah in haddii soo saari kara saamaynta ku daweynta daroogada Cancer "Avastin" la doonayo in indhaha. Reviews of saynisyahano iyo dhakhaatiir ayaa sheegaya in miisaankiisu kelli ah ee ay qayb firfircoon waa mid aad u sareeya, waayo, waa qiyaas ahaan saddex jeer mass ah ee u taagoo ee daawooyinka kale ee la saameyn la mid ah. Sidaa darteed, in aragtida, daroogada waxaa laga yaabaa in aan ka adkaan lakabka xuub isha, iyo halkan siin saamaynta ku daweynta.

Laakiin sida laga soo xigtay cilmi, "Avastin" si fiican u guskiisa galay dhamaan lakabyada ileyska, yaraynta heerka of badashada qalintaanka dhiig. Iyada oo ogaanshaha waqtiga iyo daaweyn, waxaa curin kara in ay si buuxda u ilaalin lahaa aragtida.

waxyeellooyin

Haddii aan ka fiirsan "Avastin" daroogada, tilmaamaha loo isticmaalo, dib u eegista iyo analogues la Hanuuniye isticmaalka hadalka si gaar ah oo ku saabsan soo dhoweynta gudaha, taas oo sida caadiga ah dhacdaa in lagu daaweeyo kansarka. Sidaa darteed, dhibaatooyinka soo raaca daawada waa sida soo socota:

• dhiig bax gudaha ah,
• hypertension,
• khaladaad jirta marinka dheef shiidka,
• proteinuria;
• dermatitis,
• neuropathy;
• asthenia.

Liiska waxyeellooyinka marka la isticmaalayo daawada inta lagu guda jiro daawaynta waa mid aad u ballaaran, sida marka la isticmaalayo wax daawo ah oo lagu daweeyo kansarka.

Codsiga in indhaha

Laakiin haddii ay dhacdo this daroogada aan la maamulo intravenously, oo si toos ah oo hallawda ah. Iyo marka labaad, qiyaasta waa wayn uga duwan wixii loo isticmaalaa in cudurka kansarka. Tusaale ahaan, la isku duro intravenously ku saabsan 500 mg oo daroogada ah, halka isha - 1.25 mg.

Si kastaba ha ahaatee, mid ka mid saamayn dhinac helo "Avastin" jira: dhiig meesha la muday, dareenka iyo inuu dillaaco saameen gubanaya. No calaamadaha xun daran oo la aqoonsaday ama cilmi ama ku dhaqanka.

Qadarka Qaadashada

1.25 qiyaasta mg waxaa maamula jidhka oo hallawda bishiiba mar, ama saddex ama afar jeer. ka dibna aad qiimaysid kartaa saamaynta therapy daroogada "Avastin" ee indhaha. Reviews of bukaan ayaa muujinaya in isla markiiba ka dib markii koorso of horumar ku toosan muuqaal ah lagu arkay 4 of 10 maadooyinka. In 6 ka mid ah 10 qof oo daaweyn keenaysaa in xasilinta of view, waa, si loo yareeyo heerka horumarka iyo badashada nabaro xagtin gaddoonka ah.

Saamaynta waa in ileyska noqdo khafiif ah, in uu yahay, waxay kordhisaa ay permeability iyo xoogga unugyada isha. Caadi ahaan, bukaanku uu horumar ku toosan muuqaal ah ka dib markii la isku duro hore iyo irbado xiga xoojiyaan saamaynta kaliya. Inta jeer ee aad u baahan tahay in ay ku soo celiyaan muday, taas oo ku xidhan anatomy Aadanaha. Sida laga soo xigtay tirakoob, dabcan xiga ee irbado fuliyay 2-3 bilood.

sababo

Daawada waxaa si adag laguma talinayo carruurta, haweenka uurka leh iyo hooyooyin carruurtaada nuujiya. Sidoo kale, daryeel weyn waa in la dalbadaa "Avastin" haddii ay dhacdo in ay jirto cillad ah ee beerka iyo kelyaha, gaar ahaan la'aan functional ah xubnaha.

Laakiin waa in aan xisaabta ku xaqiiqada ah in sababo codsan kaliya marka intravenously maamulo, iyo marka la siiyo cirbad galay isha, waxay leeyihiin waxaa laga yaabaa in haboonaan lahayn. Si kastaba ha ahaatee, go'aanka magacaabidda daroogada "Avastin" ee indhaha, dib u eegista ah kaas oo laga heli karaa rugta kasta oo ku haboon, waa in dhakhtar sameeyo.

Si kastaba ha ahaatee, waa in la xusuustaa in isticmaalka classical of daroogada, dhakhaatiir si xoog leh lagula talinayaa in ay iyaga isku ilaaliyaan si looga fogaado uur aan la rabin. Isticmaalka daroogada xal daaweyn for indhaha, sidoo kale, waa in ay tixgelisaa macluumaadka this, ku hawlanaa qorsheynta qoyska.

analogs

In dunida si ay u badbaadin view loo isticmaalo waqti dheer, laakiin sababtan aawadeed loo isticmaalaa daawooyin kale sida Macugen iyo Lucentis. Laakiin sanadihii la soo dhaafay waxaa jiray waxbarashada iyo aad u badan in ay sheegayaan in "Avastin" waa mid aad wax ku ool ah ee indhaha. Laakiin ilaa inta uu jiro wax macluumaad ah oo ku saabsan saamaynta mudada dheer ee la isticmaalayo daroogada si loogu daweeyo ee isha, waxaa si rasmi ah u noqon doonaa daroogada lagu daaweyn jiray burooyinka kansarka.

Si aad u taariikhda, ee-hadal insert uusan oran wax ku saabsan daaweynta ee isha. Sidaa darteed, isha keliya ee warar ku saabsan isticmaalka "Avastin" daroogada ee indhaha - eegista. Price of daroogada waa wax daacad, taasoo ku sii awoodi karo marka loo eego facooda.

"Analog" Ereyga guud ahaan waxaa loola jeedaa daroogada a in uu leeyahay qaab-dhismeedka la mid ah, qayb ka mid ah oo firfircoon. On suuqa dawooyinka Ruush daroogada waxaa, kaas oo la go'aamin karaa by barbar kooban, isagoo bartay dukumentiyada, taas oo ka mid ah ku lifaaqan "Avastin" Buuggan daroogada edbinta. Analogues, ee safafka qiimaha ka awoodi karo in ay aad qaali u, leedahay liiska la midka ah ee muujinaya. Laakiin hab la mid ah garoomada waxaa sabab u ah qaybaha kale.

daawooyinkan, kaas oo laga heli karaa farmashiye kasta, waxaa ka mid ah:

• "Arzerra."
• "Atsellbiya".
• "Vectibix".
• "Lyophilisate Herceptin".
• "Herceptin".
• "Campath".
• "MabThera".
• "Pereta."
• "Removab."
• "Rituximab".
• "Erbitux".

Saxnaanta ku-codsiga

maanta daawada rasmiga ah ma ku talinaynaa isticmaalaya "Avastin" ee indhaha. Reviews bukaannada inta badan wanaagsan ah, laakiin waxaa jira degree miisaan weyn ee halista, taas oo u baahan in la ogaado.

Waxaa jira khilaaf ah ee la xidhiidha "Avastin" daroogada: Tilmaamaha loogu isticmaalo indhaha (wakiillada dib u eegista sayniska iyo ilo kale oo sidoo kale) ma ogola isticmaalka lacagta ee daaweynta ee isha. saaraha ee daroogada si rasmi ah leeyahay in midkoodna asalka ah version a generic daroogada "Bevacizumab", soo saaray Russia midna waa in aan la isticmaali ee indhaha. Xaqiijinta macluumaadka laga heli karaa goobta Roszdravnadzor.

Laakiin on khayraadka gaar ah, sida goobaha ka go'an in ay indhaha, inta badan aad macluumaad ku saabsan sida daroogada waa mid aad u wax ku ool ah in cudurada isha ka heli kartaa. Tan waxa u sabab xaqiiqada ah in cilmi baadhis ku saabsan isticmaalka daroogada this ayaa la sameeyay oo ay fuliyeen ilaa iyo haatan, oo muujinaysa natiijooyin wanaagsan. Si kastaba ha ahaatee, ka hor inta macluumaadka la xiriira nabadgelyo buuxda oo daroogada ku saabsan asalka ah ee tayada sare, tilmaamaha Sugnaaday ma in lagu daro qaybta "Tilmaamayaasha Isticmaalka".

isticmaalka xaaladaha

Marka tan la eego, "Avastin" waxaa loo isticmaalaa oo kaliya xaaladaha degdegga ah, marka kale waa khasaare dhamaystiran oo aragga. In tijaabo ah, mid ka mid ah rugaha Ruush ogaaday in duritaanka "Avastin" ma noqonin mid horseeda in cawaaqib xun, ma aragga iyo ma keeni indho la'aan. Laakiin bukaan ka cawday lahaa gilgilay oo indhaha ku gubanaya.

Sidaas darteed, "Avastin" - daroogada aadka wax ku ool ah oo lagu daweeyo burooyinka kansarka. Practice noqday qaado "Avastin" ee indhaha, bukaanka ratings leeyihiin inta badan wanaagsan. Laakiin marka doorasho u baahan tahay inaad door biday in ay isticmaalka kaliya kuwa daawooyinka si gaar ah loogu talagalay si ay u xaliyaan dhibaato gaar ah, gaar ahaan suuqa dawooyinka horay waxaa jira qalab khaas ah oo uu yarayn karaa horumarka ee retinopathy diabetic iyo foomka qoyan ee AMD.

Sidaa darteed, "Avastin" waxaa loo isticmaali karaa oo keliya xaaladaha khatarta ah oo hoos kormeer caafimaad dhow.