Benzylpenicillin sodium cusbo: tilmaamaha loo isticmaalo. xeerarka codsiga

In this article ayaan ka hadli doonaa oo ku saabsan diyaarinta sida "benzylpenicillin sodium cusbo". Tilmaamaha loogu isticmaalo, tilmaamo, qiyaasta iyo talooyinka loogu isticmaalo in lagu daboolay ee maqaalka. Intaa waxaa dheer, waxaan ka fiirsan guryaha pharmacological sida daroogada, waxyeelada suurtogalka ah iyo isdhexgalka daroogada lala qaato dawooyinka kale.

wadaraha

Daawada waa wakiil antimicrobial iyo antibiotic ah ay leeyihiin koox penicillin ah. Benzylpenicillin cusbo sodium laftiisa, tilmaamaha loo isticmaalo kaas oo loo hoos ku soo bandhigi doono waxaa soo saaray fangaska kala duwan.

Daroogooyinka in kooxdan waxa loo isticmaalaa maamulka muruqyada dhexdooda, saamaynta on unugyada kala duwan iyo xubnaha taas oo dhiigga gaarsiisaa qadar yar oo ah penicillin. Si daroogada waxay bilaabeen inay leeyihiin saamayn on xudunta maskaxda iyo laf-dhabarta iyo xuubka, subarachnoid maamulo.

Benzylpenicillin cusbo sodium, tilmaamaha loo isticmaalo: tallaabo pharmacologically

Daawada waa wax ku ool ka dhanka ah bakteeriyada garaam-positive, taasoo ka mid ah:

• ✰Malax mid;
• streptococci,
• PNEUMOKOCKER;
• diphtheria ,
• anthrax coli,
• laylinta (badbaaday ay ka maqan yihiin oxygen) sporulating dhengedihii.

Intaas waxaa sii dheer, daroogada waa firfircoon ka dhanka ah Gram cocci negative (meningococcus, gonococcus), spirochetes, actinomycetes iyo sheyga kale. cusbo sodium penicillin waa natiijo la'aan fayrusyada, rickettsiae, fangaska, protozoa.

Drug nooc u adkaysta of ✰Malax mid, kuwaas oo awood u leh soo saarista penicillinase eulayska, burbureen benzylpenicillin. medicament The muujinayaa hawl yar daaweynta aeruginosa Pseudomonas, bakteeriyada mindhicirka iyo sheyga kale, kuwaas oo ay awoodaan in ay qoondeeyaan tiro kala duwan ee penicillinase.

Pharmacokinetics

In daroogada muruqyada dhexdooda si degdeg ah uu galo dhiigga, xaggee loo gacangeliyey dheecaannada jidhka iyo unugyada. Iyadoo la tixgelinayo dheecaanka lafdhabarka, waxaa guskiisa in qadar yar oo ah penicillin. fiirsashada ku badan yahay dhiigga ka dib markii ay maamulka intramuscularly arkay ka dib markii 30-50 min. Haddii daroogada waxaa subcutant maamula, heerka of nuugista waa la dhimay iyo tirada ugu badan ee walxaha ku jira dhiigga lagu arkay doonaa saacad.

Saddex saacadood ka dib markii la isku duro (subcutaneous ama duridda) ee benzylpenicillin raad keliya weli ku jira dhiigga. Sidaa darteed, si ay u ilaaliyaan tirada badan ee daroogada ee jirka muddo dheer, waxaa lagama maarmaan ah si aad isugu durto iyada oo afar saacadood kasta.

Marka intravenously maamulay, ay fiirsashada of daroogada si degdeg ah dhaco. Oo inta aad qaadanaysid afka benzylpenicillin waa la wada baabbi'iyey by penicillinase (enzyme) iyo casiir gastric.

daroogada raaca raaca kaadida.

maragga

Waxay waa in si taxadir leh loo soo bartay ka hor ballanta daroogada sida cusbo sodium penicillin, tilmaamaha loo isticmaalo, qiyaasta iyo tilmaamo loogu isticmaalo. Bal aan ka bilowno dambaysta ah. Sayidka, daroogada la qoray:

• in cudurrada sambabada iyo neef-mareenka;
• cudurada septic daran;
• endocarditis bakteeriyada,
• sepsis;
• cudurada iyo nabro qaba cudurka oo ka mid ah unugyada jilicsan, maqaarka iyo xub-axaleedka;
• gubasho,
• barar ah laf-dhabarta iyo maskaxda, hargahood oo mazgovyh;
• pleurisy carow ah;
• peritonitis;
• cystitis,
• Pius iyo septicaemia,
• osteomyelitis;
• diphtheria,
• qandho iyo casaan,
• jabtada,
• erysipelas;
• Infections in dhallaanka;
• anthrax;
• waraabowga;
• actinomycosis;
• inflammations dumarka kala duwan;
• cudurada bararka cunaha, dhegta iyo sanka.

Shuruudaha isticmaalka iyo qiyaasta

Iyada oo ku xidhan nooca daaweynta cudurka la isticmaalayo benzylpenicillin cusbo sodium daroogada la maamulo laga yaabaa. Tilmaamaha loogu isticmaalo, wadada ka mid ah maamulka iyo qiyaasta ay suuragal tahay in la tixgeliyo noo by qaybtan.

koorsada daawada daroogada socon karaa, iyadoo ku xiran cudurka, ka 4 todobaad ilaa 2 bilood ama ka badan. Daawada waxa loo qaadan karaa siyaabaha soo socda:

• Intramuscularly in Rubuca sare sare ee Salalka ah. diyaarinta waxaa la badhxay ka hor maamulka ee debeda, biyo, novocaine sodium ama xal chloride.
• Xididka - .. Kaliya cudurro daran sida, sida meningitis, endocarditis bakteeriyada, septicaemia, iwm Daawada waxaa maamula 4 saacad kasta ama faleebo joogto ah - 30 dhibcood halkii daqiiqo 6-12 saacadood.
• Waxa kale oo laga yaabaa in la endolyumbalno benzylpenicillin cusbo sodium. Tilmaamaha loogu isticmaalo (habka codsanaya) waxay bixisaa hab caabuq ku dhaca maskaxda iyo laf-dhabarta, oo ay ku jiraan xuubabka maskaxda. daroogada waxaa lagu duraa si tartiib ah - 1-2 daqiiqo.
• Waxaa jira kiisas benzylpenicillin loo isticmaalo isku duro iyo Axdigu u bararka. Tusaale ahaan, marka actinomycosis, leishmaniasis maqaarka, pyoderma chronic iyo xanuunada kale ee maqaarka faafa.
• Iyada oo ku neefsasho - for the daaweynta iyo ka hortaga cudurada sambabada iyo marinada hawada. Ujeedada this, qaso xalka sodium chloride benzylpenicillin ama biyo arimaha debeda. Neefsasho wax ka badan 2 jeer maalintii. Waarta hal daaweyn - laga bilaabo 10 ilaa 30 daqiiqo.
• Waxaa sidoo kale lagu mudaa saabka pleural ama xuubka hoose ee peritonitis purulent ama pleurisy.
• In foomka of xashiyihii, cadar, dhaymo qoyan, looshan iyo budo - gubashada, boogaha of unug jilicsan, iyo al osteomyelitis.
• Sidoo kale, xal daroogada loo isticmaalo daweynta cudurada neef-mareenka sare iyo indhaha.

Penicillin waxaa loo isticmaali karaa in therapy wada jir ah ula antibiotics kale iyo diyaarinta sulfanilamide. Sidee tahay xoojin doonaa saamaynta ay ku daweyn of daroogada loo isticmaalo.

waxyeellooyin

Waxa kale oo ay yeelan karaan saamayn xun ah ee sodium benzylpenicillin. Tilmaamaha loogu isticmaalo baaqaday in ay muujiyeen maamulka xididka of daroogada inta badan.

Asal ahaan, waxyeelo la xidhiidha cadaanyo in daroogada. Waxaa ka mid ah astaamaha loo kasin arkay:

• candidiasis;
• finan;
• qandho,
• madax xanuun,
• qarqaryo,
• xanuun wadajirka ah;
• Cudurka anjioedema,
• eosinophilia;
• noocyada kala duwan ee dermatitis,
• qandho,
• Lymphadenopathy;
• lama filaan ah anaphylactic - xaaladaha aad dhif u ah.

sababo

bukaan oo dhan ma u tagi kartaa therapy la medicament cusbo ah sodium benzylpenicillin. Tilmaamaha loogu isticmaalo iyo xeerarka maamulka bixiyaan tiro ka mid ah sababo. Ka mid ah iyaga,

• cudurada xasaasiyad sida urtikaria, sanboorka, neefta bronki, iwm.,
• diidmo in taagayo penicillin,
• jawaabcelin aan caadi ahayn in ay daroogada,
• Cudurka caabbi pathogene qiyaas unit of benzylpenicillin ah.

hordhaca ah ee endolyumbarnym daroogada awood u mamnuucay in qalalka.

Uurka iyo nuujinta

Layqaan ah inta ay uurka leedahay oo keliya haddii faa'iidada daaweynta haweenka waa ka weyn yahay khatarta iman karta si ay ilmaheeda aan dhalan. Haddii kale, daawada aan la maamulo. ratio khatarta iyo hufnaan la go'aamiyo uu dhakhtarka xaadirka ah.

Haddii loo baahdo, maamulka daroogada lagu jiro nuujinta waa in ay joojiyaan naasnuujinta.

guryaha

walax Drug benzylpenicillin cusbo sodium ayaa qaab budo cad crystalline wanaagsan dhadhan qadhaadh oo u diyaarsan milma ee dareeraha.

Daawada waxaa si fudud burburiyey acids, alkalis, wakiilada oksidheeyeyaal, penicillinase enzyme, iyo sidoo kale kulaylinta. Diyaari walax daroogada waa in ay ahaadaan isla markiiba ka hor maamulka.

tallaabooyin taxaddar

Daawada waxaa maamula oo kaliya in isbitaalka by warqad dhakhtar oo hoos kormeer. Iyada oo marinka ee therapy in la xusuustaa in dose benzylpenicillin ku filnayn ama joojinta hore ee daaweynta waxay keeni kartaa in formation of nooc u adkaysta of sheyga. Haddii ay dhacdo in iska caabin ah daaweynta daroogada la sii antibiotics kale.

janjeera ayaa si dareen diidmo oo xasaasiyadeed wada maamula daroogada antihistaminic waa benzylpenicillin sodium. Tilmaamaha loogu isticmaalo (tallaabo daroogada iyada oo si faahfaahsan u gaar Qoorna) wuxuu ka warrami in marka a therapy daliilka xasaasiyad bukaanka isla markiiba joojiyay.

In kooxaha qaar ka mid ah bukaanka (waayeelka, carruurta yaryar, daciifiyey by cudur) waxaa laga yaabaa in ay iska caabin ah benzylpenicillin, kaas oo keena horumarinta superinfection.

Iyada oo la isticmaalo daba dheeraaday, antibiotic waa la baabi'iyay karaan ama qayb ahaan lagu halligay microflora xiidmaha, taasoo keentay in wax soo saarka hoos u vitamins ee group B. Sidaa darteed prophylactically in bukaanka inta badan vitamins qoray B1, B12, iyo kuwa kale.

Haddii, ka dib markii bilowgii therapy 3 maalmood ayaa la ogaaday ma wax saameyn ah, waxaa lagama maarmaan ah si ay u tagaan daawaynta isku daro ama ku wareejiso ah antibiotic cusub.

ganaaxyada

Taxadarka dadka loo xilsaaray la wadnaha iyo shaqada kelyaha oo yaraada benzylpenicillin cusbo sodium. Tilmaamaha loogu isticmaalo sidoo kale ku taliyey in fiiro gaar ah la siiyo kuwa bukaan dhawray diidmo in cephalosporins.

Sababtoo ah waxaa macquul ah ee superinfection fangas lagu talinayaa in la qoro wakiilada anti-fangas.

Dhexgalka daroogooyinka kale

In magacaabista antibiotics, kuwaas oo ay leeyihiin bacteriostatic, tallaabo bactericidal of penicillin la dhimay.

Diyaarinta "Probenecid" ayaa guri si loo yareeyo dheecaanka embriyaha ah antibiotic in ay keentey in la kordhiyo heerka dhiigga dambaysta ah iyo, sida natiijo ah, la kordhiyo wakhtiga ay ka saareen jidhka ka.